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Lidocaine

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Identification
Molecular formula
C14H20N2O
CAS number
137-58-6
IUPAC name
[5-chloro-2-(methylamino)phenyl]-(2-chlorophenyl)methanone
State
State

At room temperature, Lidocaine is typically a solid in the form of a crystalline powder.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.1676g/cm3
Appearence

Lidocaine typically appears as a white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of [5-chloro-2-(methylamino)phenyl]-(2-chlorophenyl)methanone

The solubility of [5-chloro-2-(methylamino)phenyl]-(2-chlorophenyl)methanone can be described through several key attributes:

  • Polar and Non-polar Interactions: This compound contains both polar and non-polar groups, which can significantly influence its solubility in various solvents.
  • Solvent Dependency: Typically, molecules with polar functional groups tend to dissolve well in polar solvents such as water, while those with more hydrophobic characteristics are likely to be more soluble in organic solvents (like ethanol or acetone).
  • Temperature Effects: As with many organic compounds, solubility can increase with temperature. Therefore, heating can enhance its solubility in suitable solvents.
  • Presence of X-Cl Bonds: The presence of chlorine atoms may also affect intermolecular interactions, potentially leading to different solubility profiles depending on the solvent used.

Overall, the solubility of [5-chloro-2-(methylamino)phenyl]-(2-chlorophenyl)methanone is not straightforward and can be highly variable depending on the solvent and conditions it is exposed to. Therefore, understanding the specific environment and medium is crucial for predicting its behavior in solution.

Interesting facts

Interesting Facts about [5-chloro-2-(methylamino)phenyl]-(2-chlorophenyl)methanone

This intriguing compound belongs to the class of organic molecules known as ketones. It exhibits a variety of captivating characteristics and potential applications, making it a subject of interest in both pharmaceutical and chemical research. Here are some key highlights:

  • Pharmaceutical Potential: Compounds similar to [5-chloro-2-(methylamino)phenyl]-(2-chlorophenyl)methanone are often investigated for their medicinal properties. Researchers explore their potential as potent drugs, particularly in the field of antidepressants and antipsychotics.
  • Structure-Activity Relationship (SAR): By modifying various parts of the compound, scientists can study how changes in structure affect biological activity. This has immense implications in drug design, allowing for the optimization of efficacy and safety.
  • Synthesis Pathways: The synthesis of this compound can involve multiple steps, often starting from simpler aromatic compounds. Understanding these synthesis pathways is crucial for chemists aiming to produce the compound efficiently for research or pharmaceutical applications.
  • Chirality and Isomerism: The presence of chiral centers in its structure leads to the possibility of multiple isomers. Investigating the effects of these isomers can provide insight into the compound's mechanism of action in biological systems.
  • Environmental Considerations: As a chlorinated compound, it prompts discussions on environmental impact and sustainability. Chemists are increasingly focused on developing greener synthesis methods to minimize harmful byproducts.

In summary, [5-chloro-2-(methylamino)phenyl]-(2-chlorophenyl)methanone showcases the intersection of chemistry and medicinal research, providing endless opportunities for exploration. As the quote goes, "The good chemist is a wizard who can turn the plainest of elements into life-saving concoctions." Expanding our understanding of such compounds drives innovation in multiple scientific fields.

Synonyms
5621-86-3
2',5-Dichloro-2-(methylamino)benzophenone
BENZOPHENONE, 2',5-DICHLORO-2-METHYLAMINO-
(5-Chloro-2-(methylamino)phenyl)(2-chlorophenyl)methanone
EINECS 227-050-8
BRN 0793664
Methanone, (5-chloro-2-(methylamino)phenyl)(2-chlorophenyl)-
Methanone, [5-chloro-2-(methylamino)phenyl](2-chlorophenyl)-
[5-Chloro-2-(methylamino)phenyl](2-chlorophenyl)methanone
DTXSID00204748
DTXCID30127239
227-050-8
2-Methylamino-2',5-dichlorobenzophenone
[5-chloro-2-(methylamino)phenyl]-(2-chlorophenyl)methanone
2'-Chloro-2-methylamino-5-chlorobenzophenone
WUH83J8VCG
4-CHLORO-2-(2-CHLOROBENZOYL)-N-METHYLANILINE
(Methanone, [5-chloro-2-(methylamino)phenyl](2-chlorophenyl)-)
UNII-WUH83J8VCG
SCHEMBL9726995
MFCD01662307
AKOS028108405
SB82404
2',5-dichloro-2-methylaminobenzophenone
2-methylamino-2',5-dichlor-benzophenone
2-Methylamino-5,2'-dichlorobenzophenone
2', 5-dichloro-2-methylaminobenzophenone
2-methylamino-2', 5-dichlorobenzophenone
AS-65044
2-methylamino-2' ,5-dichlor-benzophenone
CS-0047335
NS00033484
A10877
Q63392700
[5-Chloro-2-(methylamino)phenyl](2-chlorophenyl)methanone #