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Clemastine

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Identification
Molecular formula
C17H18ClNO
CAS number
5573-19-3
IUPAC name
[5-chloro-2-(methylamino)phenyl]-phenyl-methanone
State
State

At room temperature, Clemastine is typically found in a solid crystalline form.

Melting point (Celsius)
133.00
Melting point (Kelvin)
406.15
Boiling point (Celsius)
438.20
Boiling point (Kelvin)
711.35
General information
Molecular weight
267.79g/mol
Molar mass
267.7280g/mol
Density
0.9320g/cm3
Appearence

Clemastine is usually found as a white or almost white crystalline powder. It is odorless or may have a faint characteristic odor.

Comment on solubility

Solubility of [5-chloro-2-(methylamino)phenyl]-phenyl-methanone

The solubility of [5-chloro-2-(methylamino)phenyl]-phenyl-methanone can exhibit diverse characteristics depending on various conditions. Here are some key points to consider:

  • Polarity: The presence of the chlorine substituent and the methylamino group suggests that this compound may have polar characteristics, potentially increasing solubility in polar solvents.
  • Solvent Compatibility: Likely soluble in solvents such as:
    • Water (to a limited extent)
    • Alcohols (e.g., methanol, ethanol)
    • Dimethyl sulfoxide (DMSO)
  • Temperature Dependence: Solubility often changes with temperature; typically, higher temperatures can increase solubility due to greater molecular motion and interactions.
  • pH Influence: The solubility may also be affected by pH; the methylamino group can protonate in acidic conditions, potentially increasing solubility in acidic media.

In summary, the solubility of [5-chloro-2-(methylamino)phenyl]-phenyl-methanone is influenced by its molecular structure, the choice of solvent, temperature, and environmental pH. As such, assessing solubility under specific experimental conditions is crucial for understanding its behavior in various applications.

Interesting facts

Interesting Facts about [5-chloro-2-(methylamino)phenyl]-phenyl-methanone

[5-chloro-2-(methylamino)phenyl]-phenyl-methanone is a fascinating compound recognized for its diverse applications in the field of chemistry and pharmacology. Here are some noteworthy aspects:

  • Structure and Function: The structure of this compound includes a chlorinated phenyl ring as well as a methylamino group, which plays a significant role in its reactivity and biological interactions. The positioning of these functional groups contributes to its overall stability and functionality.
  • Therapeutic Potential: Compounds like [5-chloro-2-(methylamino)phenyl]-phenyl-methanone are often investigated for their *potential therapeutic applications* in treating various medical conditions, including their roles in the development of pharmaceuticals.
  • Importance in Organic Synthesis: This compound can serve as a valuable intermediate in organic synthesis. Its unique functional groups allow chemists to modify and create a variety of other chemical structures, making it a key player in synthetic organic chemistry.
  • Research and Development: Ongoing research continues to explore the *biochemical properties* of this compound. Studying such molecules enhances our understanding of drug design and mechanism of action, particularly concerning its potential impact on the central nervous system.
  • Safety and Environmental Considerations: While working with such compounds, it's essential to consider safety protocols and environmental impacts. Researchers often conduct detailed studies on the *toxicity and biodegradability* of new chemical entities to ensure they are safe for both laboratory use and potential applications.

In summary, [5-chloro-2-(methylamino)phenyl]-phenyl-methanone is not just a compound of interest due to its chemical structure but also because of its potential implications in various fields, particularly in medicinal chemistry. As scientists continue to unravel the complexities of this molecule, we can expect significant advancements and discoveries in medical research.

Synonyms
1022-13-5
5-Chloro-2-(methylamino)benzophenone
5-Chloro-2-methylaminobenzophenone
2-Methylamino-5-chlorobenzophenone
Methanone, [5-chloro-2-(methylamino)phenyl]phenyl-
BRN 0882187
BENZOPHENONE, 5-CHLORO-2-(METHYLAMINO)-
EINECS 213-822-1
(5-Chloro-2-(methylamino)phenyl)phenylmethanone
D4GD5770PI
Methanone, (5-chloro-2-(methylamino)phenyl)phenyl-
DTXSID4061416
2-(N-methylamino)-5-chlorobenzophenone
DIAZEPAM IMPURITY D [EP IMPURITY]
TEMAZEPAM IMPURITY A [EP IMPURITY]
RO-5-4365
CHLORO-2-METHYLAMINOBENZOPHENONE, 5-
[5-Chloro-2-(methylamino)phenyl]phenylmethanone
DIAZEPAM IMPURITY D (EP IMPURITY)
TEMAZEPAM IMPURITY A (EP IMPURITY)
2-(Methylamino)-5-chlorobenzophenone
2-MACB
DTXCID3032707
213-822-1
(5-Chloro-2-(methylamino)phenyl)(phenyl)methanone
[5-chloro-2-(methylamino)phenyl]-phenylmethanone
2-benzoyl-4-chloro-N-methylaniline
MFCD00008284
[5-Chloro-2-(methylamino)phenyl]-phenylmethanone (5-Chloro-2-(methylamino)benzophenone)
UNII-D4GD5770PI
Oprea1_680102
BIDD:GT0238
SCHEMBL333291
2-Methylamino-5-chlorbenzophenon
2-Methylamino-5-chlorbenzophenone
AC1105
Benzophenone, 2-acetamido-5-chloro-
AKOS000120857
CS-W012707
FC38184
HY-W011991
AC-10169
AS-11966
PD163859
SY037878
DB-014567
5-Chloro-2-(methylamino)benzophenone, 99%
C2281
NS00023126
EN300-20890
A800545
SR-01000395967
SR-01000395967-1
[5-chloranyl-2-(methylamino)phenyl]-phenyl-methanone
Q27276093
Z104484472