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4-Chloroaniline hydrochloride

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Identification
Molecular formula
C6H7Cl2NS
CAS number
20265-96-7
IUPAC name
(5-chloro-2-sulfanyl-phenyl)ammonium;chloride
State
State

At room temperature, 4-Chloroaniline hydrochloride is in a solid state. It is stable under normal temperatures and pressures, provided it is stored properly to avoid moisture absorption.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.00
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.00
General information
Molecular weight
162.04g/mol
Molar mass
162.0350g/mol
Density
1.4900g/cm3
Appearence

4-Chloroaniline hydrochloride typically appears as a white to off-white crystalline powder. It has a fine texture and may exhibit a slight odor characteristic of chlorinated aromatic compounds. It is hygroscopic, which means it can absorb moisture from the air.

Comment on solubility

Solubility of (5-chloro-2-sulfanyl-phenyl)ammonium chloride

The solubility of (5-chloro-2-sulfanyl-phenyl)ammonium chloride in different solvents can reveal much about its chemical nature and potential applications. In general, the solubility characteristics of this compound can be summarized as follows:

  • Water Solubility: This compound is likely to be soluble in water due to the presence of the ammonium (–NH4) group, which often enhances solubility in polar solvents.
  • Solvent Interactions: Given its unique sulfanyl (–SH) and chloro (–Cl) substituents, the compound may exhibit varying solubility in organic solvents, with potential solubility in:
    • Alcohols (e.g., ethanol)
    • Dimethyl sulfoxide (DMSO)
    • Aqueous solutions with varying pH
  • Ionization Consideration: The ionization of the ammonium group can lead to increased solubility in polar solvents, whereas non-polar solvents may show poor solubility.

In summary, the solubility of (5-chloro-2-sulfanyl-phenyl)ammonium chloride is influenced by its ionic characteristics and functional groups. As a rule of thumb, compounds containing ammonium salts tend to favor solubility in water. Consistency in testing solubility conditions, such as temperature and solvent type, is key to obtaining reliable results.

Interesting facts

Interesting Facts about (5-chloro-2-sulfanyl-phenyl)ammonium;chloride

(5-chloro-2-sulfanyl-phenyl)ammonium;chloride is a compound that holds significant interest within the realm of medicinal chemistry and materials science. Here are some fascinating insights:

  • Pharmaceutical Relevance: This compound may serve as a precursor for various pharmaceutical agents, particularly due to its unique structural features that can influence biological activity.
  • Sulfur's Role: The presence of the sulfanyl group adds not only to the compound's chemical properties but also enhances its reactivity, potentially leading to novel biochemical pathways.
  • Chlorination Impact: The chlorination at the 5-position can impact the compound’s interaction with biological targets, making it a focus of study for understanding structure-activity relationships in drug design.

Potential Applications

The functionalities gained from the inclusion of both the sulfanyl and ammonium moieties suggest potential applications in:

  • Antimicrobial agents
  • Research reagents for organic synthesis
  • Stabilizing agents in various chemical processes

Research Directions

Ongoing research may focus on:

  • Developing derivatives with improved efficacy
  • Exploring the mechanisms of action at the molecular level
  • Investigating its potential as a biosensor material

As a future scientist or student, understanding 5-chloro-2-sulfanyl-phenylammonium;chloride's properties and implications could inspire innovative approaches to drug design and synthetic chemistry. The versatility of this compound exemplifies how small changes in molecular structure can lead to significant advancements in technology and health.

Synonyms
2-Mercapto-5-chloroanilinium chloride
(5-chloro-2-sulfanylphenyl)azanium;chloride
NS00042562