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(5-chloro-2,3-dihydrobenzofuran-2-yl)methanamine

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Identification
Molecular formula
C9H10ClNO
CAS number
913614-18-3
IUPAC name
(5-chloro-2,3-dihydrobenzofuran-2-yl)methanamine
State
State
Solid at room temperature. Typically, compounds like this, with aromatic structures, tend to be stable solids due to the presence of pi bonding, which adds additional stability to the molecular structure.
Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
288.00
Boiling point (Kelvin)
561.15
General information
Molecular weight
183.63g/mol
Molar mass
183.6340g/mol
Density
1.1820g/cm3
Appearence

The compound is expected to be a crystalline solid. Crystalline solids are characterized by a well-ordered structure, with the constituent particles arranged in a repeating pattern, typically resulting in clear, hard materials. The specific appearance may vary, but they generally have a well-defined shape.

Comment on solubility

Solubility of (5-chloro-2,3-dihydrobenzofuran-2-yl)methanamine

The solubility of (5-chloro-2,3-dihydrobenzofuran-2-yl)methanamine can be influenced by several factors, making it a fascinating subject of study. Typically, the solubility of organic compounds like this one is affected by:

  • Polarity: The presence of the functional groups in (5-chloro-2,3-dihydrobenzofuran-2-yl)methanamine plays a critical role in its interaction with solvents.
  • Hydrogen Bonding: This compound may participate in hydrogen bonding, which can enhance its solubility in polar solvents.
  • Temperature: As with many organic compounds, an increase in temperature can lead to greater solubility.
  • pH of the Solution: The protonation state of the amine group can affect solubility; it is more soluble in acidic conditions where it remains protonated.

In general, hydrophobic interactions can decrease solubility in water, while the presence of functional groups may allow for increased solubility in organic solvents. Therefore, the solubility landscape of (5-chloro-2,3-dihydrobenzofuran-2-yl)methanamine can be summarized as:

  1. Greater solubility in polar solvents due to potential hydrogen bonding.
  2. Lower solubility in non-polar solvents owing to the hydrophobic benzofuran structure.
  3. Increased solubility in acidic solutions due to protonation of the amine group.

To conclude, while the precise solubility must be determined experimentally, this compound shows promising characteristics for solubility that depend on various environmental and chemical factors.

Interesting facts

Interesting Facts about (5-chloro-2,3-dihydrobenzofuran-2-yl)methanamine

The compound (5-chloro-2,3-dihydrobenzofuran-2-yl)methanamine is a fascinating member of the benzofuran family, which is notable for its diverse range of biological activities. This particular compound integrates a unique structural motif that benefits various scientific explorations.

Key Features

  • Unique Structure: The presence of a benzofuran core provides distinct electronic and spatial properties that can influence reactivity and interaction with biological systems.
  • Biological Relevance: Compounds containing aminomethyl groups, such as methanamine derivatives, are integral in pharmaceutical chemistry. They often show promise as precursors to more complex drug molecules.
  • Halogen Influence: The chlorine atom at the 5-position can significantly alter the compound's reactivity and biological interactions, offering exciting avenues for research into medicinal chemistry.

In the realm of organic synthesis, this compound can serve as a key intermediate in creating more complex structures. As noted by many researchers, "the ability to manipulate specific functional groups can lead to novel compounds with enhanced effectiveness or reduced side effects." This underscores the importance of compounds like (5-chloro-2,3-dihydrobenzofuran-2-yl)methanamine not only in basic science but also in the context of developing new therapeutic agents.

Ultimately, the exploration of this compound reveals much about the intricate balance between structural characteristics and functional outcomes, making it a worthy subject of study for chemists and pharmacologists alike.

Synonyms
SCHEMBL715447
AKOS014775299