Interesting facts
Interesting Facts about 5-Chloro-3-(4-chlorophenyl)-N-(4-fluoro-2-methyl-phenyl)-2-hydroxy-benzamide
This compound is a remarkable example of the intricate world of organic chemistry, particularly in the realm of medicinal chemistry and drug design. Here are some intriguing aspects:
- Structural Complexity: The compound features a complex molecular structure with multiple functional groups, including chloro, fluoro, hydroxy, and amide groups. This diversity contributes to its unique properties and potential biological activity.
- Pharmaceutical Relevance: Compounds like this one are often investigated for their potential therapeutic applications, particularly in fields such as oncology and neurology. The substitution patterns can affect interactions with biological targets.
- Fluorine's Influence: The presence of fluorine atoms in organic compounds can enhance metabolic stability, oral bioavailability, and lipophilicity. This compound illustrates how strategic fluorination can lead to improved pharmacokinetic profiles.
- Halogenation: The incorporation of chlorine and fluorine atoms can significantly alter the electronic properties of the aromatic system, potentially leading to increased potency or selectivity in biological interactions.
- Hydrogen Bonding: The hydroxyl group in this compound opens avenues for hydrogen bonding interactions, which can be critical for binding affinity to enzyme active sites or receptor sites in biological systems.
- Ligand Design: The intricate design of this compound reflects important concepts in ligand-based drug design, emphasizing how modifications in structure can lead to vastly different biological outcomes.
As you delve deeper into the study of compounds like 5-chloro-3-(4-chlorophenyl)-N-(4-fluoro-2-methyl-phenyl)-2-hydroxy-benzamide, remember that chemistry is as much about the **structure** and **functionality** as it is about the **application** in real-world scenarios. Each compound tells a story of how molecular features can influence broader outcomes in pharmacology and therapeutic efficacy.
Synonyms
24283-57-6
DTXSID30179016
3-BIPHENYLCARBOXY-o-TOLUIDIDE, 4',5-DICHLORO-4''-FLUORO-2-HYDROXY-
RefChem:1069012
DTXCID60101507
4',5-Dichloro-N-(4-fluoro-2-methylphenyl)-2-hydroxy(1,1'-biphenyl)-3-carboxamide
4',5-Dichloro-N-(4-fluoro-2-methylphenyl)-2-hydroxy-(1,1'-biphenyl)-3-carboxamide
4',5-Dichloro-N-(4-fluoro-2-methylphenyl)-2-hydroxy-[1,1'-Biphenyl]-3-carboxamide
Monsanto CP-48985
CP 48985
ENT 27,349
NSC 190947
AI3-27349
Salicylanilide, 5-chloro-3-(4-chlorophenyl)-4'-fluoro-2'-methyl-
1,1'-Biphenyl-3-carboxamide, 4',5-dichloro-N-(4-fluoro-2-methylphenyl)-2-hydroxy-
(1,1'-Biphenyl)-3-carboxamide, 4',5-dichloro-N-(4-fluoro-2-methylphenyl)-2-hydroxy-
Solubility of 5-chloro-3-(4-chlorophenyl)-N-(4-fluoro-2-methyl-phenyl)-2-hydroxy-benzamide
The solubility of 5-chloro-3-(4-chlorophenyl)-N-(4-fluoro-2-methyl-phenyl)-2-hydroxy-benzamide in various solvents is a critical parameter that influences its applications in chemical research and industry. Here are some key points to consider:
In summary, the solubility profile of 5-chloro-3-(4-chlorophenyl)-N-(4-fluoro-2-methyl-phenyl)-2-hydroxy-benzamide can be influenced by solvent choice, temperature, and the chemical environment. Understanding these factors is essential for effective application in laboratories and industrial processes.