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5-Chloro-3-ethyl-1,3-benzoxazol-2-one

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Identification
Molecular formula
C9H8ClNO2
CAS number
28536-63-2
IUPAC name
5-chloro-3-ethyl-1,3-benzoxazol-2-one
State
State

At room temperature, 5-Chloro-3-ethyl-1,3-benzoxazol-2-one is typically found in a solid state.

Melting point (Celsius)
97.00
Melting point (Kelvin)
370.15
Boiling point (Celsius)
470.15
Boiling point (Kelvin)
743.30
General information
Molecular weight
211.64g/mol
Molar mass
211.6350g/mol
Density
1.3660g/cm3
Appearence

The compound 5-Chloro-3-ethyl-1,3-benzoxazol-2-one typically appears as a solid powder with a white to off-white color. Its consistency can vary depending on its purity and environmental conditions.

Comment on solubility

Solubility of 5-chloro-3-ethyl-1,3-benzoxazol-2-one

The solubility of 5-chloro-3-ethyl-1,3-benzoxazol-2-one in various solvents can be quite complex and is influenced by several factors. Understanding its solubility properties is crucial for applications in pharmaceuticals and other chemical processes. Here are some key points to consider:

  • Polar vs. Non-Polar Solvents: This compound typically exhibits better solubility in polar solvents due to its molecular structure, which includes a nitrogen atom that can engage in hydrogen bonding.
  • Temperature Dependence: The solubility may increase with temperature; therefore, measuring solubility at different temperatures can provide valuable insights.
  • pH Influence: The solubility could be affected by the pH of the solution, particularly if it can ionize under certain conditions, making it more soluble in either acidic or basic environments.
  • Solvent Systems: Miscibility with other solvents, such as mixtures of water and organic solvents, can enhance its overall solubility, promoting various applications.

In summary, the solubility of 5-chloro-3-ethyl-1,3-benzoxazol-2-one demonstrates the importance of solvent choice and environmental conditions. Further studies can reveal more detailed solubility parameters, which are essential for optimizing its use in chemical reactions and formulations.

Interesting facts

Interesting Facts about 5-chloro-3-ethyl-1,3-benzoxazol-2-one

The compound 5-chloro-3-ethyl-1,3-benzoxazol-2-one is a fascinating molecule that belongs to the benzoxazole family, which is known for its diverse applications in various fields, including pharmaceuticals and materials science.

Structural Attributes

This compound features a unique structure comprising a benzene ring fused with an oxazole ring. This configuration contributes to its chemical reactivity and makes it an essential component in synthetic chemistry. Here are some notable features:

  • Chlorine Substitution: The presence of the chlorine atom plays a pivotal role in enhancing its biological activity.
  • Ethyl Group: The ethyl group increases hydrophobic characteristics, which can affect how the compound interacts with biological systems.

Applications and Uses

5-chloro-3-ethyl-1,3-benzoxazol-2-one has significant relevance in several areas:

  • Pharmaceuticals: Compounds in the benzoxazole class are often explored for their potential as anti-inflammatory, antimicrobial, and anticancer agents.
  • Fluorescent Dyes: Its unique structural properties make it suitable for use as a fluorescent probe in various research applications.
  • Material Science: The incorporation of benzoxazole derivatives can improve the thermal stability and optical properties of polymers.

Chemical Reactions

This compound is not only of interest for its applications but also for its fascinating chemistry. It can undergo various transformations, including:

  • Nucleophilic substitutions: The chlorine atom can be displaced, allowing for the introduction of other functional groups.
  • Photochemical reactions: The molecule can absorb UV light, which can initiate reactions useful in organic synthesis.

As noted by experts, "The exploration of benzoxazole derivatives is crucial for developing new therapeutic agents." This highlights the ongoing research and interest in compounds like 5-chloro-3-ethyl-1,3-benzoxazol-2-one.

In conclusion, the unique structural characteristics and versatile applications make 5-chloro-3-ethyl-1,3-benzoxazol-2-one a compelling subject of study in both academic and industrial research settings.

Synonyms
2-BENZOXAZOLINONE, 5-CHLORO-3-ETHYL-
5-Chloro-3-ethyl-2-benzoxazolinone
5790-91-0
5-chloro-3-ethyl-1,3-benzoxazol-2-one
LHH5QQC85T
NSC 24961
BRN 0645231
NSC-24961
DTXSID60206622
2(3H)-Benzoxazolone, 5-chloro-3-ethyl-
5-CHLORO-3-ETHYL-2(3H)-BENZOXAZOLONE
DTXCID90129113
NSC24961
UNII-LHH5QQC85T
SCHEMBL6425871
WLN: T56 BNVOJ B2 HG