Interesting facts
Interesting Facts about 5-Chloro-3-(hydroxymethyl)-1,3-benzoxazol-2-one
5-Chloro-3-(hydroxymethyl)-1,3-benzoxazol-2-one, often referred to as a member of the benzoxazole family, plays a crucial role in various fields, especially in medicinal chemistry. Here are some intriguing points about this compound:
- Medicinal Potential: Compounds like 5-chloro-3-(hydroxymethyl)-1,3-benzoxazol-2-one have demonstrated significant biological activities, including antimicrobial and anticancer properties. This makes it a valuable candidate in drug design and discovery.
- Versatile Chemistry: The presence of both a chlorinated and a hydroxymethyl group allows for various possible reactions. This adds to its utility in synthetic organic chemistry, enabling chemists to explore a range of derivatives and analogs.
- Fluorescent Properties: Benzoxazole derivatives are known for their fluorescence, which can be applied in biological imaging and sensor technology. The ability to act as fluorescent probes can help researchers visualize biological processes in real-time.
- Structural Significance: The benzoxazole moiety embodies a fused ring system that influences its electronic properties, often leading to increased stability and reactivity compared to simpler structures.
- History: The incorporation of benzoxazole in pharmaceutical compounds has roots that date back to the early 20th century, showcasing the long-standing interest in this class of compounds and their derivatives.
As research continues, compounds like 5-chloro-3-(hydroxymethyl)-1,3-benzoxazol-2-one are expected to unveil new therapeutic avenues, making it an exciting topic of study in contemporary chemistry.
Synonyms
17929-34-9
N-(Hydroxymethyl)chlorzoxazone
BRN 1214145
2-BENZOXAZOLINONE, 5-CHLORO-3-HYDROXYMETHYL-
2-Benzoxazolinone-3-methanol, 5-chloro-
2(3H)-Benzoxazolone, 5-chloro-3-(hydroxymethyl)-
DTXSID80170790
DTXCID8093281
2(3H)-Benzoxazolone, 5-chloro-3-(hydroxymethyl)-(9CI)
5-chloro-3-(hydroxymethyl)-1,3-benzoxazol-2-one
5-Chloro-3-(hydroxymethyl)benzoxazol-2(3H)-one
Solubility of 5-chloro-3-(hydroxymethyl)-1,3-benzoxazol-2-one
The solubility of 5-chloro-3-(hydroxymethyl)-1,3-benzoxazol-2-one can be affected by various factors, making its understanding quite fascinating. Typically, this compound exhibits moderate solubility in polar solvents due to the presence of the hydroxymethyl (-CH2OH) group, which enhances hydrogen bonding capabilities. In contrast, its solubility in nonpolar solvents is generally low.
Key points about its solubility include:
When experimenting with this compound, it is essential to consider these factors for optimal solubility. As with many chemical compounds, conducting solubility tests in various solvents will yield practical insights into its behavior in different environments. Understanding the solubility characteristics of 5-chloro-3-(hydroxymethyl)-1,3-benzoxazol-2-one can significantly contribute to its applications in chemical synthesis and formulation development.