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5-Chloro-3-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1H-indole

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Identification
Molecular formula
C21H23ClN2O
CAS number
303827-38-3
IUPAC name
5-chloro-3-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1H-indole
State
State

At room temperature, this compound is typically found in a solid state. It is often handled in powder form for convenience in laboratory settings.

Melting point (Celsius)
209.00
Melting point (Kelvin)
482.15
Boiling point (Celsius)
524.22
Boiling point (Kelvin)
797.37
General information
Molecular weight
350.88g/mol
Molar mass
350.8450g/mol
Density
1.3200g/cm3
Appearence

This compound is typically characterized by its solid-state appearance. It may appear as a crystalline powder or in some instances as a fine solid form. The color can range from off-white to light beige depending on purity and processing conditions.

Comment on solubility

Solubility of 5-chloro-3-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1H-indole

The solubility of 5-chloro-3-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1H-indole, often influenced by its complex molecular structure, can be intriguing. This compound is characterized by its aromatic systems and functional groups which can affect its interaction with solvents. Here are some key considerations regarding its solubility:

  • Polarity: The presence of the pyrrolidine ring and ether group may increase the polarity of the molecule, suggesting that it is more soluble in polar solvents.
  • Solvent Compatibility: It is likely soluble in organic solvents such as ethanol, dichloromethane, or acetone due to its hydrophobic indole backbone.
  • Temperature Factor: Solubility can also be temperature-dependent; increasing the temperature often enhances the solubility of organic compounds.
  • pH Sensitivity: As with many heterocycles, the solubility may also vary with pH, particularly if the compound can exist in protonated forms in more acidic conditions.

In conclusion, the solubility of this compound suggests a nuanced balance of factors involving its structure, solvent characteristics, and external conditions. Understanding these aspects is crucial for its practical applications in various fields.

Interesting facts

Interesting Facts About 5-Chloro-3-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1H-indole

This compound, 5-chloro-3-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1H-indole, belongs to the indole family, which is a fascinating class of compounds in medicinal chemistry. Indoles are known for their diverse biological activities, making them a significant focus for researchers.

Key Features

  • Structural Diversity: The compound features a complex structure with multiple functional groups, making it a candidate for unique interactions in biological systems.
  • Biological Significance: Indole derivatives typically exhibit a range of pharmacological properties, including anti-inflammatory, antifungal, and antitumor activities.
  • Synthetic Pathways: The synthesis of this compound can involve various organic reactions, showcasing the versatility of indole chemistry.

Applications and Research!

Due to its unique structure, this compound is often explored in the following areas:

  • Drug Development: Compounds with indole cores are frequently investigated as potential pharmaceuticals.
  • Neuroscience Studies: The presence of a pyrrolidine ring indicates possible interactions with neurotransmitter systems, making it relevant for studying cognitive functions.
  • Material Science: Indole derivatives are also studied for their potential applications in developing organic semiconductors and dyes.

In summary, the multifaceted nature of 5-chloro-3-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1H-indole not only highlights its importance in chemical research but also suggests a myriad of applications that enhance our understanding of both organic compounds and their potential uses in medicine and technology.

Synonyms
INDOLE, 5-CHLORO-3-METHYL-2-(p-(2-(1-PYRROLIDINYL)ETHOXY)PHENYL)-
14554-85-9
BRN 1494646
5-Chloro-3-methyl-2-p-(beta-pyrrolidinoethoxy)phenylindole
5-Chloro-3-methyl-2-(p-(2-(1-pyrrolidinyl)ethoxy)phenyl)indole
5-21-04-00121 (Beilstein Handbook Reference)
DTXSID90163092