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5-Chloro-6-methoxybenzoxazol-2-amine

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Identification
Molecular formula
C8H7ClN2O2
CAS number
105294-72-4
IUPAC name
5-chloro-6-methoxy-1,3-benzoxazol-2-amine
State
State

This compound is usually found as a solid at room temperature, having a stable crystalline structure.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
378.40
Boiling point (Kelvin)
651.55
General information
Molecular weight
200.60g/mol
Molar mass
200.5900g/mol
Density
1.3600g/cm3
Appearence

5-Chloro-6-methoxy-1,3-benzoxazol-2-amine typically appears as a crystalline solid that may range from white to off-white in color. The compound's appearance can vary slightly based on its purity and specific form.

Comment on solubility

Solubility of 5-chloro-6-methoxy-1,3-benzoxazol-2-amine

The solubility of 5-chloro-6-methoxy-1,3-benzoxazol-2-amine is an important aspect to consider when evaluating its applicability in various chemical contexts. Here are some key points to note:

  • Solvent Dependence: This compound typically shows better solubility in organic solvents due to its non-polar aromatic structures.
  • Polar vs Non-Polar: While it may have limited solubility in polar solvents such as water, it can dissolve more readily in non-polar solvents.
  • pH Influence: The solubility can be influenced by the pH of the solution, as ionization of the amine group may impact the overall solubility.
  • Temperature Effects: Increased temperature often leads to increased solubility, allowing this compound to dissolve more effectively in higher temperatures.

Researchers have noted that "the specific solubility characteristics must be taken into account when developing formulations involving 5-chloro-6-methoxy-1,3-benzoxazol-2-amine." Understanding these solubility parameters is crucial for designing effective drugs and chemical applications involving this compound.

In summary, the solubility of 5-chloro-6-methoxy-1,3-benzoxazol-2-amine varies significantly based on the solvent choice, pH, and temperature, all of which should be carefully considered in practical applications.

Interesting facts

Interesting Facts about 5-Chloro-6-methoxy-1,3-benzoxazol-2-amine

This compound, known as 5-Chloro-6-methoxy-1,3-benzoxazol-2-amine, belongs to the family of benzoxazole derivatives, which have gained notable attention in medicinal chemistry due to their diverse biological activities.

Key Highlights:

  • Biological Significance: Many benzoxazole derivatives are recognized for their efficacy as anti-cancer agents, anti-inflammatory agents, and anti-microbial compounds. This particular compound may exhibit similar promising pharmacological properties.
  • Mechanism of Action: The presence of functional groups, such as chloro and methoxy, in the molecular structure often influences the compound's interaction with biological targets, including enzymes and receptors.
  • Application Potential: Due to its unique structure, this compound holds potential for development in pharmaceuticals, particularly in the creation of novel treatments for various diseases.

The compound's structure contributes to its stability and reactivity, making it an intriguing subject for further research. Scientists are continually exploring benzoxazole derivatives for their therapeutic benefits, often leading to surprising discoveries in drug development.

As a chemistry student or scientist, one may appreciate the importance of considering structure-activity relationships (SAR) in understanding how the molecular framework of compounds like this one can lead to different biological activities. The exploration of derivatives and analogs can pave the way for pioneering discoveries in the field of medicinal chemistry.

In summary, 5-chloro-6-methoxy-1,3-benzoxazol-2-amine exemplifies the potential of indole structures in pharmaceutical chemistry, and its study could lead to significant advancements in the development of new therapeutic agents.

Synonyms
2139-00-6
BRN 0910541
BENZOXAZOLE, 2-AMINO-5-CHLORO-6-METHOXY-
2-Amino-5-chloro-6-methoxybenzoxazole
DTXSID10175652
DTXCID9098143