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5-Chloro-6-methoxybenzoxazole-2(3H)-one

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Identification
Molecular formula
C8H6ClNO3
CAS number
38953-59-2
IUPAC name
5-chloro-6-methoxy-3H-1,3-benzoxazol-2-one
State
State

At room temperature, 5-Chloro-6-methoxy-3H-1,3-benzoxazol-2-one is typically in a solid state.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
211.59g/mol
Molar mass
211.5870g/mol
Density
1.3450g/cm3
Appearence

5-Chloro-6-methoxy-3H-1,3-benzoxazol-2-one appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 5-chloro-6-methoxy-3H-1,3-benzoxazol-2-one

The solubility of 5-chloro-6-methoxy-3H-1,3-benzoxazol-2-one can be an interesting topic due to its diverse applications in medicinal chemistry and material science. Understanding its solubility characteristics is essential for various formulations and reactions.

Key Points on Solubility:

  • Aqueous Solubility: This compound tends to have limited solubility in water. Factors such as temperature and pH can significantly affect its solubility profile.
  • Organic Solvents: It is usually more soluble in organic solvents like ethanol, DMSO (dimethyl sulfoxide), and acetone, making these solvents preferable for laboratory uses.
  • Influence of Substituents: The presence of Cl (chlorine) and OCH3 (methoxy) groups can enhance solubility in organic media due to their polar characteristics, which help in stabilizing interactions with solvents.

In summary, the solubility of 5-chloro-6-methoxy-3H-1,3-benzoxazol-2-one reflects a complex interplay of factors that dictate its behavior in different environments. For researchers, understanding these solubility properties is crucial for optimizing conditions for various applications:

  1. Ensure appropriate solvent selection for synthesis.
  2. Evaluate conditions for effective extraction.
  3. Design experiments considering solubility limitations.

Overall, the solubility of this compound illustrates the broader principle that solubility is not merely a chemical property but can be engineered and utilized to achieve desired outcomes in chemical research.

Interesting facts

Interesting Facts about 5-Chloro-6-methoxy-3H-1,3-benzoxazol-2-one

5-Chloro-6-methoxy-3H-1,3-benzoxazol-2-one, a multifaceted compound, showcases a blend of intriguing characteristics and applications:

  • Structural Highlights: This compound features a benzoxazole ring, which is known for its stability and pi-electron delocalization, making it a vital component in many organic compounds.
  • Pharmaceutical Potential: Benzoxazole derivatives have garnered attention for their potential as pharmacologically active agents, with implications in treating various diseases, including cancers and infections.
  • Role of Chlorine: The presence of chlorine in its structure is significant as halogenated compounds often exhibit enhanced biological activity and unique reactivity patterns.
  • Versatile Applications: Beyond pharmaceuticals, this compound may find utility in:
    • Fluorescent dyes
    • Organic light-emitting diodes (OLEDs)
    • Chemical sensors
  • Research Interest: Scientists are keenly exploring benzoxazole derivatives for innovative uses in material science and biochemistry, highlighting the compound's significance in both academic and industrial realms.

As we delve deeper into its properties and applications, 5-chloro-6-methoxy-3H-1,3-benzoxazol-2-one stands out as a fascinating subject of study in the ever-evolving field of chemistry.

Synonyms
5-Chloro-6-methoxy-2-benzoxazolinone
1750-47-6
BRN 0913074
2-BENZOXAZOLINONE, 5-CHLORO-6-METHOXY-
DTXSID20169921
DTXCID9092412
5-chloro-6-methoxy-3H-1,3-benzoxazol-2-one
5-Chloro-6-methoxy-2,3-dihydrobenzoxazole-2-one
2(3H)-Benzoxazolone, 5-chloro-6-methoxy-
5-Chloro-6-methoxybenzo[d]oxazol-2(3H)-one
5-Chloro-6-methoxy-2(3H)-benzoxazolone