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Clomipramine

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Identification
Molecular formula
C19H23ClN2O
CAS number
303-49-1
IUPAC name
(5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-2-yl)methanol
State
State

At room temperature, clomipramine exists as a solid. It is generally available in the form of tablets or capsules when used for its intended applications in medical treatments.

Melting point (Celsius)
68.50
Melting point (Kelvin)
341.70
Boiling point (Celsius)
545.80
Boiling point (Kelvin)
818.80
General information
Molecular weight
314.86g/mol
Molar mass
314.8400g/mol
Density
1.2000g/cm3
Appearence

Clomipramine typically appears as a white or slightly off-white crystalline powder. It is often sold in a more stable solid salt form as clomipramine hydrochloride, which aids in preserving its therapeutic characteristics and facilitating easier administration in pharmaceutical settings.

Comment on solubility

Solubility of (5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-2-yl)methanol

The solubility profile of (5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-2-yl)methanol can be influenced by its complex structure. Here are some key considerations:

  • Polarity: The presence of hydroxyl groups typically enhances solubility in polar solvents like water.
  • Hydrophobic Character: The tricyclic framework and substitution patterns may introduce hydrophobic regions, impacting its solubility.
  • Solvent Compatibility: This compound may show varying degrees of solubility in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO).
  • Temperature Influence: Elevated temperatures might promote solubility by increasing molecular movement and overcoming intermolecular forces.

As a general rule, "like dissolves like," meaning that the solvent's characteristics can significantly dictate the solubility behavior of this compound. Understanding these nuances is critical for applications in chemical synthesis or drug formulation.

Interesting facts

Exploring 5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-2-yl)methanol

This intriguing compound, 5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-2-yl)methanol, belongs to the class of nitrogen-containing heterocycles, which are key components in various biological and pharmaceutical applications. Here are some fascinating facts that highlight its importance and potential:

  • Heterocyclic Chemistry: The presence of nitrogen atoms in its structure suggests potential uses in biologically active compounds. Heterocycles have been extensively studied for their role in medicinal chemistry.
  • Applications in Drug Development: This compound's complex structure may lead to the development of new therapeutic agents, particularly for conditions related to neurotransmitter functions, owing to similar known compounds.
  • Chirality: With multiple stereo centers, this compound underscores the significance of chirality in drug design, as different enantiomers can exhibit vastly different biological activities.
  • Research Interests: Chemists are continuously interested in compounds like this for their unique properties, especially in the fields of organic synthesis and materials science.

The study of such compounds not only furthers our understanding of chemical reactivity but also opens pathways to innovative solutions in various scientific fields. As one researcher aptly said, "The future of chemistry relies on the ability to manipulate complex molecules in ways that challenge our current understanding."

In conclusion, 5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-2-yl)methanol illustrates the vast potential that nitrogen-rich heterocycles hold for advancing both scientific knowledge and practical applications in medicine and beyond.

Synonyms
BRN 4140797
3889-03-0
1H-AZEPINO(5,4,3-cd)INDOLE-2-METHANOL, 3,4,5,6-TETRAHYDRO-9-CHLORO-6-METHYL-
9-Chloro-6-methyl-3,4,56-tetrahydro-1H-azepino(5,4,3-cd)indole-2-methanol
DTXSID00959660
(9-Chloro-6-methyl-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)methanol