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Clozapine

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Identification
Molecular formula
C18H19ClN4
CAS number
5786-21-0
IUPAC name
5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13),9-pentaene
State
State

At room temperature, Clozapine is typically in a solid state as a crystalline powder. It is not hygroscopic, meaning it does not readily absorb moisture from the atmosphere.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.20
Boiling point (Celsius)
576.50
Boiling point (Kelvin)
849.70
General information
Molecular weight
326.83g/mol
Molar mass
326.8310g/mol
Density
1.2800g/cm3
Appearence

Clozapine appears as an off-white to yellowish crystalline powder. The powder is typically homogeneous and free-flowing, lacking any significant clumps or aggregates.

Comment on solubility

Solubility of 5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13),9-pentaene

Understanding the solubility of 5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13),9-pentaene is crucial for various applications in chemical science, especially in the realms of pharmaceuticals and organic synthesis. This compound presents unique structural features that can affect its solubility in different solvents.

Key Factors Influencing Solubility

  • Polar vs. Non-polar Solvents: The solubility is likely influenced by the presence of polar and non-polar characteristics in its molecular structure. Compounds with polar functional groups tend to dissolve better in polar solvents (like water), while non-polar compounds prefer non-polar solvents (like hexane).
  • Hydrogen Bonding: The ability to form hydrogen bonds can significantly enhance solubility in polar solvents. The presence of nitrogen in this compound may facilitate such interactions.
  • Structural Complexity: The intricate structure with multiple rings could lead to steric hindrance, potentially affecting its dissolution rate and the formation of stable solvate complexes.

In conclusion, while 5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13),9-pentaene holds interesting potential for solubility studies, the specific solubility profile would require experimental determination to accurately reveal its behavior in various solvents. As always, exploring solubility provides not only practical insights into reactivity and stability but also opens doors to wider applications across materials science and medicinal chemistry.

Interesting facts

Interesting Facts about 5-Chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13),9-pentaene

This fascinating organic compound is not just a series of complex symbols and numbers; it embodies a rich history of chemical research and application. Here are several intriguing facts about this compound:

  • Structural Complexity: The molecule features a unique framework characterized by its diazatricyclic structure, which contains two nitrogen atoms in a bicyclic arrangement. This complexity can lead to interesting reactivity and interaction with other molecules.
  • Potential Applications: Compounds with similar structures often find their way into advanced materials or pharmaceuticals. The nitrogen-containing heterocycles are of particular interest in medicinal chemistry, potentially leading to the development of novel therapeutics.
  • Visualization Techniques: Chemists often utilize techniques like NMR spectroscopy and mass spectrometry to elucidate the structure and behavior of such complex compounds. Understanding the electronic and spatial arrangement gives insights into their reactivity.
  • Research Interest: Due to their intricate structures, compounds of this kind are frequently the subject of academic studies, driving research into their synthesis, properties, and potential uses in various industries.
  • Environmental Considerations: As the field of green chemistry advances, the synthesis pathways for compounds like this are being reassessed to find more sustainable and environmentally friendly methods of production.

As stated by renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." In the realm of chemistry, innovative compounds like 5-chloro-9-methyl-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13),9-pentaene are ripe for exploration, promising new avenues for scientific discovery.

In summary, this compound is a treasure trove for chemists, as it bridges fundamental studies and practical applications, merging theoretical knowledge with the potential to impact real-world challenges.

Synonyms
3083-83-8
BRN 0747331
3,4-Dihydro-9-chloro-6-methyl-1H-azepino(5,4,3-cd)indole
9-Chloro-3,4-dihydro-6-methyl-1H-azepino(5,4,3-cd)indole
1H-AZEPINO(5,4,3-cd)INDOLE, 3,4-DIHYDRO-9-CHLORO-6-METHYL-
5-23-08-00096 (beilstein handbook reference)
DTXSID20953029
9-Chloro-6-methyl-4,5-dihydro-3H-azepino[5,4,3-cd]indole