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Diflumetorim

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Identification
Molecular formula
C19H12Cl3NO2
CAS number
119200-28-9
IUPAC name
5-chloro-N-(3,4-dichlorophenyl)-2-hydroxy-3-phenyl-benzamide
State
State

At room temperature, diflumetorim is found in a solid crystalline state.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.20
Boiling point (Celsius)
571.40
Boiling point (Kelvin)
844.60
General information
Molecular weight
398.67g/mol
Molar mass
398.6700g/mol
Density
1.4820g/cm3
Appearence

Diflumetorim typically appears as an off-white to pale yellow crystalline solid.

Comment on solubility

Solubility of 5-chloro-N-(3,4-dichlorophenyl)-2-hydroxy-3-phenyl-benzamide

5-chloro-N-(3,4-dichlorophenyl)-2-hydroxy-3-phenyl-benzamide is a complex organic compound, and its solubility can be influenced by a variety of factors. Understanding its solubility behavior is crucial for applications in both laboratory and pharmaceutical settings. Here are some key points to consider:

  • Polarity: The presence of hydroxyl groups in the molecular structure often enhances solubility in polar solvents like water, while the aromatic rings could contribute to solubility in non-polar solvents.
  • Hydrogen bonding: The hydroxyl (-OH) functionality can engage in hydrogen bonding, which may facilitate solubility in polar solvents.
  • Temperature effects: Solubility may increase with higher temperatures, which can promote the interaction between solute and solvent molecules.
  • pH sensitivity: The acidic or basic nature of the solution can affect the ionization of the compound, thereby altering its solubility.

It's essential to note that solubility can vary significantly between different media; hence, empirical testing may be necessary for precise determinations. As a general rule, "like dissolves like" often serves as a guiding principle when predicting solubility patterns.

Interesting facts

Interesting Facts about 5-chloro-N-(3,4-dichlorophenyl)-2-hydroxy-3-phenyl-benzamide

This compound is a fascinating member of the benzamide family, which is notable for its various biological activities and applications in medicinal chemistry. Here are some key points that highlight its significance:

  • Antimicrobial Activity: Compounds of this type have shown promising results against a range of microorganisms, making them potential candidates for the development of new antimicrobial agents.
  • Pharmacological Potential: Benzamides often play roles in drug design due to their ability to modify biological pathways. Researchers are exploring their utility in treating various conditions, including cancer and inflammation.
  • Chlorine Substitution: The presence of chlorine substituents in this compound is particularly noteworthy; they can enhance lipophilicity and bioactivity, which is crucial for pharmacological efficacy.
  • Structure-Activity Relationship (SAR): Understanding the SAR of benzamide derivatives can lead to improved efficacy and reduced toxicity in drug candidates, making this compound a focal point in ongoing research.
  • Interdisciplinary Research: The study of this compound often intersects various fields such as organic chemistry, pharmacology, and toxicology, promoting collaboration among scientists.

Overall, 5-chloro-N-(3,4-dichlorophenyl)-2-hydroxy-3-phenyl-benzamide stands as a prime example of how subtle structural variations in organic compounds can lead to significant differences in biological activity. As research continues, this compound is likely to contribute to advancements in therapeutic development and our understanding of chemical interactions in biological systems.

Synonyms
Monsanto CP-42366
OM-1460
5212-99-7
ENT 27,136
BRN 2771226
CP-42366
AI3-27136
5-Chloro-N-(3,4-dichlorophenyl)-2-hydroxy-(1,1'-biphenyl)-3-carboxamide
(1,1'-Biphenyl)-3-carboxamide, 5-chloro-N-(3,4-dichlorophenyl)-2-hydroxy-
3-BIPHENYLCARBOXANILIDE, 3'',4'',5-TRICHLORO-2-HYDROXY-
DTXSID10200130
DTXCID10122621