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Tropicamide

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Identification
Molecular formula
C17H24ClN2O2
CAS number
1508-75-4
IUPAC name
5-chloropentyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium;chloride
State
State

At room temperature, tropicamide is usually in a solid state. It is stable under normal conditions and commonly used in eye drop formulations.

Melting point (Celsius)
95.00
Melting point (Kelvin)
368.15
Boiling point (Celsius)
670.00
Boiling point (Kelvin)
943.15
General information
Molecular weight
342.88g/mol
Molar mass
342.8830g/mol
Density
1.1600g/cm3
Appearence

Tropicamide is typically a white to off-white crystalline powder. It is often found in its pure form for pharmaceutical uses.

Comment on solubility

Solubility of 5-chloropentyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium;chloride

The solubility of a compound like 5-chloropentyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium;chloride is influenced by its molecular structure and the presence of charged functional groups. This type of compound typically demonstrates interesting solubility properties due to the following factors:

  • Ionization: As a quaternary ammonium salt, the chloride component suggests that the molecule is likely to be highly soluble in polar solvents like water.
  • Hydrophilicity: The presence of the ammonium group increases the hydrophilic character, allowing the compound to interact favorably with water molecules.
  • Hydrophobic interactions: However, the long hydrocarbon chain (5-chloropentyl) might also impart some degree of hydrophobicity, affecting the solubility when mixed with nonpolar solvents.

Overall, while one might expect the solubility in water to be substantial, it is crucial to consider the balance between the hydrophilic and hydrophobic parts of the molecule. Hence, the solubility can be summarized as:

  1. Good solubility in aqueous environments due to the ionic nature of the compound.
  2. Reduced solubility in non-aqueous solvents, primarily influenced by the hydrophobic chain.

In conclusion, the complex interplay of functional groups within 5-chloropentyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium;chloride provides a fascinating case for understanding solubility in different solvent systems.

Interesting facts

Interesting Facts about 5-chloropentyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium chloride

This compound is a fascinating example of the intersection between organic chemistry and pharmacology. Known for its diverse potential applications, here are some interesting aspects:

  • Design and Functionality: The unique structure of this compound features a quaternary ammonium salt, which is often associated with its capacity to function as a surfactant or a quaternary ammonium compound. Surfactants are crucial in various fields ranging from detergents to cosmetics due to their ability to reduce surface tension.
  • Antimicrobial Properties: Many compounds of this type exhibit notable antimicrobial activity, which makes them ideal candidates for disinfectants and antiseptics. The presence of the halogen atom (chlorine) in its structure often enhances its potency against a wide spectrum of microorganisms.
  • Pharmaceutical Relevance: Its parent structure suggests potential applications in drug design, especially in targeting specific biological pathways. Compounds that resemble this one are often researched for their roles in treating various conditions, including infections and certain forms of cancer.
  • Synthesis and Reactivity: The synthetic pathway of this compound is integral to its study. Chemists often explore various synthetic methods to optimize yield and purity while minimizing environmental impacts. This encourages a continual evolution of techniques in synthetic organic chemistry.
  • Analytical Techniques: The characterization of this compound may entail advanced analytical methods, such as NMR spectroscopy, mass spectrometry, and chromatographic techniques. These methods are crucial for confirming structural integrity and understanding reactivity.

As with many compounds in organic chemistry, understanding its properties opens the door to innovations in both science and technology. The ongoing research surrounding compounds similar to 5-chloropentyl-[2-(2,6-dimethylanilino)-2-oxo-ethyl]-methyl-ammonium chloride may lead to breakthroughs in materials science and medicinal chemistry.

Synonyms
25027-86-5
RefChem:1075201
Acetamide, 2-((5-chloropentyl)methylamino)-N-(2,6-dimethylphenyl)-, hydrochloride (1:1)
Acetamide, 2-((5-chloropentyl)methylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride
W 49172
2-((5-Chloropentyl)methylamino)-2',6'-acetoxylidide hydrochloride
2',6'-ACETOXYLIDIDE, 2-((5-CHLOROPENTYL)METHYLAMINO)-, MONOHYDROCHLORIDE