Skip to main content

Barbituric acid

ADVERTISEMENT
Identification
Molecular formula
C4H4N2O3
CAS number
67-52-7
IUPAC name
5-cinnamylidenehexahydropyrimidine-2,4,6-trione
State
State

At room temperature, barbituric acid is in a solid state, appearing as a white crystalline powder.

Melting point (Celsius)
248.00
Melting point (Kelvin)
521.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
128.10g/mol
Molar mass
128.0990g/mol
Density
1.4350g/cm3
Appearence

Barbituric acid is a white crystalline solid that is primarily known for its reference in studies of barbiturate drugs. The solid is often used in the pharmaceutical industry as a starting material for many commercial barbiturate drugs.

Comment on solubility

Solubility of 5-cinnamylidenehexahydropyrimidine-2,4,6-trione

The solubility of 5-cinnamylidenehexahydropyrimidine-2,4,6-trione is a fascinating topic that draws attention due to its unique structure. The compound consists of multiple functional groups that can influence its solubility properties in various solvents.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar and non-polar regions within the molecule can significantly influence its interactions with solvents. Polar solvents such as water may dissolve compounds that exhibit polar characteristics.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds with solvents can enhance solubility. Strong hydrogen bond donors and acceptors typically increase compatibility with polar solvents.
  • Temperature: Generally, **increased temperature** enhances the solubility of solids in liquids. However, this may vary based on the compound's structure and the specific solvent used.
  • pH Levels: The pH of the solvent can also affect solubility, especially if the compound contains ionizable functional groups.

As a result, while precise solubility data for 5-cinnamylidenehexahydropyrimidine-2,4,6-trione may not be readily available, one can predict that its solubility behavior could be influenced by the factors mentioned above. Future studies could provide a clearer picture of its solubility characteristics in various solvents, potentially unlocking its applications in medicinal chemistry and beyond.

Interesting facts

Interesting Facts about 5-Cinnamylidenehexahydropyrimidine-2,4,6-trione

5-Cinnamylidenehexahydropyrimidine-2,4,6-trione is a fascinating compound in the realm of organic chemistry, particularly known for its unique structure and potential applications. Here are some intriguing aspects of this compound:

  • Unique Structure: This compound features a pyrimidine ring, which is a key structural motif in numerous biological systems, including nucleic acids.
  • Versatile Applications: Compounds like this one are often explored in pharmaceuticals for their potential to act as intermediates in the synthesis of more complex drugs and biologically active molecules.
  • Chemical Reactivity: The presence of the cinnamylidene group may impart interesting reactivity, making it applicable in various organic reactions, such as aldol condensation and Michael addition.
  • Natural Product Precursor: Structurally related compounds have been identified in nature, leading researchers to explore potential natural pathways for synthesis.
  • Research Potential: Ongoing studies aim to elucidate its properties further, especially concerning its bioactivity and usefulness in medicinal chemistry.

As a chemist or a student delving into organic chemistry, understanding compounds like 5-cinnamylidenehexahydropyrimidine-2,4,6-trione can spark creativity and innovation in chemical research. Its intriguing features may inspire the design of new compounds with enhanced efficacy in drug development.

Synonyms
Maybridge4_000641
SCHEMBL11598594
CRQHPZFBGAKYRX-UHFFFAOYSA-N
AKOS030699094