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Phenobarbital

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Identification
Molecular formula
C12H12N2O3
CAS number
50-06-6
IUPAC name
5-cyclohexyl-1-phenyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, phenobarbital is typically in a solid state.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
550.00
Boiling point (Kelvin)
823.15
General information
Molecular weight
232.24g/mol
Molar mass
232.2390g/mol
Density
1.2860g/cm3
Appearence

Phenobarbital typically appears as a white, crystalline powder. It is odorless and has a slightly bitter taste. The compound is often found in this powdered form for pharmaceutical use.

Comment on solubility

Solubility of 5-cyclohexyl-1-phenyl-hexahydropyrimidine-2,4,6-trione

The solubility of 5-cyclohexyl-1-phenyl-hexahydropyrimidine-2,4,6-trione can be affected by various factors. It's essential to consider the following aspects when discussing its solubility:

  • Polarity: Due to the presence of multiple carbon and nitrogen atoms in its structure, the polarity of the compound plays a significant role in determining its solubility in various solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds can influence solubility, particularly in polar solvents like water.
  • Solvent Type: Non-polar solvents, such as hexane or toluene, may dissolve this compound better than polar solvents due to its hydrocarbon chains.
  • Temperature: As with many organic compounds, solubility often increases with temperature, potentially allowing for greater dissolution in warmer conditions.

In conclusion, while there may not be a wide array of definitive solubility data available for this specific compound, it is likely to exhibit pronounced solubility characteristics based on the interplay of its structure and the nature of the solvent used. Thus, experimental solubility testing is advisable for precise determination.

Interesting facts

Interesting Facts about 5-Cyclohexyl-1-phenyl-hexahydropyrimidine-2,4,6-trione

5-Cyclohexyl-1-phenyl-hexahydropyrimidine-2,4,6-trione is a fascinating compound with unique structural properties and potential applications in various fields. Below are some interesting insights about this compound:

  • Structural Characteristics: This compound features a hexahydropyrimidine ring that is functionalized at multiple positions, leading to a complex three-dimensional structure. The presence of the cyclohexyl and phenyl groups adds to its steric bulk, which can influence its reactivity and interactions with other molecules.
  • Biological Activity: Compounds containing pyrimidine rings are often investigated for their biological properties. Many derivatives have been shown to exhibit antimicrobial and antifungal activities, indicating that 5-cyclohexyl-1-phenyl-hexahydropyrimidine-2,4,6-trione may also hold promise as a lead compound for drug development.
  • Synthetic Pathways: The synthesis of this compound may involve multi-step reactions, including cyclization and functional group transformations. Its complex structure presents a valuable challenge for synthetic chemists looking to explore new methodologies.
  • Research Potential: With ongoing interest in heterocyclic chemistry and medicinal compounds, 5-cyclohexyl-1-phenyl-hexahydropyrimidine-2,4,6-trione is likely to be a topic of research in developing new pharmaceuticals or materials with enhanced properties.
  • Applications in Material Science: Beyond biological applications, compounds with extensive π-conjugation like this one can exhibit interesting electronic properties, raising potential applications in organic electronics and photonic devices.

In summary, 5-cyclohexyl-1-phenyl-hexahydropyrimidine-2,4,6-trione serves as an intriguing example of how chemical structure can dictate functionality, making it an exciting subject for both research and application in various scientific disciplines. As the famous chemist Linus Pauling once stated, "The best way to have a good idea is to have a lot of ideas." This compound could be a step towards generating innovative solutions in modern chemistry.

Synonyms
5-Cyclohexyl-1-phenylbarbituric acid
20272-08-6
5-cyclohexyl-1-phenyl-1,3-diazinane-2,4,6-trione
BRN 0686725
BARBITURIC ACID, 5-CYCLOHEXYL-1-PHENYL-
5-Cyclohexyl-1-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-cyclohexyl-1-phenyl-
SCHEMBL17358726
DTXSID60942391
5-Cyclohexyl-6-hydroxy-3-phenylpyrimidine-2,4(3H,5H)-dione