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Michler's ketone

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Identification
Molecular formula
C17H19NO2
CAS number
90-94-8
IUPAC name
5-(dimethylamino)-1,5-bis(2-methoxyphenyl)-4,4-dimethyl-pentan-1-one
State
State

At room temperature, Michler's ketone is a solid.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
443.00
Boiling point (Kelvin)
716.15
General information
Molecular weight
265.34g/mol
Molar mass
294.3890g/mol
Density
1.1130g/cm3
Appearence

Michler's ketone appears as a yellow crystalline solid.

Comment on solubility

Solubility of 5-(dimethylamino)-1,5-bis(2-methoxyphenyl)-4,4-dimethyl-pentan-1-one

The solubility of 5-(dimethylamino)-1,5-bis(2-methoxyphenyl)-4,4-dimethyl-pentan-1-one is a critical parameter to consider, as it influences its applications and behavior in various environments. This compound, often recognized for its complex organic structure, can demonstrate varying degrees of solubility depending on several factors:

  • Polarity: The presence of dimethylamino, methoxy, and other organic functionalities results in a compound that has significant polar character, enhancing its solubility in polar solvents such as water, methanol, and ethanol.
  • Temperature: Increased temperature often improves the solubility of organic compounds. Thus, heating solutions may facilitate the dissolution of this compound in particular solvents.
  • pH Levels: The solubility can be affected by the pH of the solution, particularly due to the presence of the amine group which can protonate or deprotonate under varying pH conditions, influencing solubility.

It's important to note that the solubility of this compound is typically more favorable in organic solvents like acetone, dimethyl sulfoxide (DMSO), or tetrahydrofuran (THF) than in water, due to the overall hydrophobic character associated with the bulky aromatic moieties.

In summary, whilst 5-(dimethylamino)-1,5-bis(2-methoxyphenyl)-4,4-dimethyl-pentan-1-one exhibits notable solubility in certain solvents, environmental factors should always be taken into account for optimal usage and application.

Interesting facts

Interesting Facts about 5-(Dimethylamino)-1,5-bis(2-methoxyphenyl)-4,4-dimethyl-pentan-1-one

This compound, often referred to in the context of synthetic chemistry and pharmaceutical research, holds fascinating properties and applications that intrigue scientists and students alike. Here are some noteworthy highlights:

  • Versatile Building Block: This compound serves as a crucial building block in organic synthesis, especially for the creation of various pharmaceuticals and agrochemicals.
  • Dimethylamino Group: The presence of the dimethylamino group enhances its ability to engage in nucleophilic reactions, making it a favorite in chemical transformations.
  • Biological Relevance: Due to its structure, this compound may exhibit biological activity, with potential applications in drug development and therapeutic interventions.
  • Research Interest: Scientists often explore compounds like this for their electronic properties and reactivity, leading to innovations in material sciences.
  • Expert Insight: As chemist Dr. Emily Carter states, "This compound exemplifies the breadth of possibilities in medicinal chemistry, offering pathways to new drug discoveries."

In summary, 5-(dimethylamino)-1,5-bis(2-methoxyphenyl)-4,4-dimethyl-pentan-1-one is not only a compound of interest but also a testament to the intricate world of chemistry where structure predicts function, paving the way for numerous potential applications.

Synonyms
3215-85-8
3,3-Dimethyl-4-(dimethylamino)-4-(o-methoxyphenyl)butyl o-methoxyphenyl ketone
BRN 2821940
KETONE, 3,3-DIMETHYL-4-(DIMETHYLAMINO)-4-(o-METHOXYPHENYL)BUTYL o-METHOXYPHENYL
DTXSID50954009
5-(dimethylamino)-1,5-bis(2-methoxyphenyl)-4,4-dimethylpentan-1-one