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5-(Dimethylamino)-1H-indole-3-carbaldehyde

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Identification
Molecular formula
C11H12N2O
CAS number
114223-69-3
IUPAC name
5-(dimethylamino)-1H-indole-3-carbaldehyde
State
State

At room temperature, 5-(Dimethylamino)-1H-indole-3-carbaldehyde is typically found in the solid state as a powder. It is stable under standard environmental conditions.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
196.00
Boiling point (Kelvin)
469.15
General information
Molecular weight
202.24g/mol
Molar mass
202.2400g/mol
Density
1.2400g/cm3
Appearence

5-(Dimethylamino)-1H-indole-3-carbaldehyde is a solid compound that typically appears as a crystalline powder. The color can vary from white to slightly yellow or off-white, depending on the specific purity and form of the sample.

Comment on solubility

Solubility of 5-(dimethylamino)-1H-indole-3-carbaldehyde

5-(dimethylamino)-1H-indole-3-carbaldehyde is a compound known for its unique structural features which influence its solubility characteristics.

In terms of solubility, this compound exhibits:

  • Moderate solubility in polar solvents: It typically dissolves in solvents like water, methanol, and ethanol due to its ability to form hydrogen bonds with these solvents.
  • Poor solubility in non-polar solvents: Solvents such as hexane or toluene are less effective at dissolving this compound, as the non-polar characteristics of these solvents do not interact favorably with the polar functional groups present.
  • Dependency on pH: The solubility may also vary with changes in pH. For instance, under acidic conditions, the compound can become protonated, increasing its solubility in water.

As a result, when considering the application or synthesis involving 5-(dimethylamino)-1H-indole-3-carbaldehyde, one must take into account these solubility factors for optimal results.

Interesting facts

Interesting Facts about 5-(dimethylamino)-1H-indole-3-carbaldehyde

5-(dimethylamino)-1H-indole-3-carbaldehyde, often referred to as an important intermediate in organic synthesis, boasts an intriguing structure that combines indole’s aromaticity with an aldehyde functional group. Here are some captivating points to consider:

  • Role in Research: This compound is widely recognized in the field of medicinal chemistry for its role in the synthesis of various pharmaceuticals and organic compounds.
  • Fluorescent Properties: It exhibits interesting fluorescent properties, making it a potential candidate for use in bioimaging and as a fluorescent probe.
  • Reactivity: The aldehyde group plays a crucial role in its reactivity, allowing for further functionalization and derivatization, paving the way for the creation of even more complex structures.
  • Biological Activity: Compounds with similar structures have been investigated for their biological activity, including potential applications as anticancer agents.
  • Electronic Properties: The presence of the dimethylamino group contributes to its electronic properties, affecting how it interacts with light and other chemicals.

This compound is a testament to the beauty of chemical diversity and the innovative possibilities within the realm of organic chemistry. As one delves deeper into the study of 5-(dimethylamino)-1H-indole-3-carbaldehyde, the layers of its importance in both academic research and practical applications become increasingly evident. Truly, it's a compound that embodies the intersection of creativity and science!

Synonyms
3-Formyl-5-dimethylamino indole
BRN 0389928
INDOLE-3-CARBOXALDEHYDE, 5-DIMETHYLAMINO-
6843-27-2
5-Dimethylaminoindole-3-carboxaldehyde
DTXSID90218551
5-22-13-00021 (Beilstein Handbook Reference)
DTXCID40141042
SCHEMBL25253642