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Dapoxetine

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Identification
Molecular formula
C21H26N2O1
CAS number
119356-77-3
IUPAC name
5-(dimethylamino)-2-ethyl-2-(1-naphthyl)pentanenitrile
State
State
At room temperature, dapoxetine is typically found in a solid state, specifically as a crystalline powder.
Melting point (Celsius)
175.50
Melting point (Kelvin)
448.65
Boiling point (Celsius)
376.30
Boiling point (Kelvin)
649.45
General information
Molecular weight
341.46g/mol
Molar mass
341.4590g/mol
Density
1.1189g/cm3
Appearence

Dapoxetine is a crystalline powder that is white to off-white in color. It is typically available in tablet form for its application in pharmaceuticals.

Comment on solubility

Solubility of 5-(dimethylamino)-2-ethyl-2-(1-naphthyl)pentanenitrile

The solubility characteristics of 5-(dimethylamino)-2-ethyl-2-(1-naphthyl)pentanenitrile are interesting and can influence its applications in various fields. Understanding its solubility is crucial for effective utilization in chemical processes and formulations.

In general, the solubility of this compound can be influenced by several factors:

  • Polarity: The presence of the dimethylamino group contributes to moderate polarity, potentially enhancing solubility in polar solvents.
  • Functional Groups: The naphthyl ring may affect the compound's ability to dissolve in non-polar solvents due to its hydrophobic character.
  • Temperature: Solubility often increases with temperature, making temperature-dependent studies valuable for optimizing solubilization.
  • pH Environment: The ionization state of the amine group may vary with pH, affecting solubility in certain environments.

For practical applications, it is often said that "the solubility profile of a compound is as important as its reactivity." The effective solubility of this compound can thus determine its suitability for various chemical reactions and interactions.

Further, one may consider performing solubility tests in a range of solvents such as:

  • Water
  • Ethanol
  • Dichloromethane
  • Acetone

Overall, while specific solubility data may vary, understanding the underlying principles gives insights into how 5-(dimethylamino)-2-ethyl-2-(1-naphthyl)pentanenitrile can be effectively utilized in chemical syntheses and formulations.

Interesting facts

Interesting Facts About 5-(Dimethylamino)-2-ethyl-2-(1-naphthyl)pentanenitrile

5-(Dimethylamino)-2-ethyl-2-(1-naphthyl)pentanenitrile is a fascinating compound that has garnered attention in the fields of organic chemistry and medicinal chemistry. Here are some key points that highlight its significance:

  • Structural Diversity: This compound features a unique structure with a dimethylamino group, a naphthyl moiety, and a nitrile functional group, showcasing how functional group orientation can affect reactivity and interaction in biological systems.
  • Pharmacological Potential: Compounds like this one are often studied for their potential pharmaceutical applications, particularly as they possess a structure that may mimic biologically active molecules.
  • Research Applications: It serves as a valuable compound in studying structure-activity relationships (SAR), which is crucial for developing new drug candidates. The presence of multiple functional groups allows researchers to investigate their effects on biological activity.
  • Synthetic Methods: The synthesis of this compound involves several intriguing organic reactions, making it an excellent case study for students learning about complex organic synthesis. Understanding the pathway to its synthesis can enhance skills in retrosynthetic analysis.
  • Reactivity Exploration: The nitrile group provides potential sites for nucleophilic attacks, thus broadening the reactivity of the molecule in various organic reactions.

In conclusion, 5-(Dimethylamino)-2-ethyl-2-(1-naphthyl)pentanenitrile truly embodies the creativity and complexity of organic synthesis. The exploration of its properties can not only advance our understanding of chemical behavior but may also pave the way for innovative drug development.

Synonyms
13531-98-1
alpha-(3-(Dimethylamino)propyl)-alpha-ethyl-1-naphthaleneacetonitrile
BRN 2755844
1-NAPHTHALENEACETONITRILE, alpha-(3-(DIMETHYLAMINO)PROPYL)-alpha-ETHYL-
DTXSID20928954
5-(dimethylamino)-2-ethyl-2-(naphthalen-1-yl)pentanenitrile