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Dextropropoxyphene

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Identification
Molecular formula
C22H29NO2
CAS number
469-62-5
IUPAC name
5-(dimethylamino)-2-ethyl-2-(1-naphthyl)pentanoic acid
State
State

At room temperature, dextropropoxyphene commonly exists as a solid. It is stable under normal temperature and pressure conditions typically found indoors.

Melting point (Celsius)
40.50
Melting point (Kelvin)
313.65
Boiling point (Celsius)
494.90
Boiling point (Kelvin)
768.05
General information
Molecular weight
339.47g/mol
Molar mass
339.4720g/mol
Density
0.9880g/cm3
Appearence

Dextropropoxyphene appears as white crystalline powder. It is usually odorless and can be slightly bitter in taste. The compound is usually dispensed in a tablet or capsule form for ease of oral consumption, though the appearance in its raw form is powdery.

Comment on solubility

Solubility of 5-(dimethylamino)-2-ethyl-2-(1-naphthyl)pentanoic acid

The solubility of 5-(dimethylamino)-2-ethyl-2-(1-naphthyl)pentanoic acid in various solvents plays a crucial role in its applications and biological relevance. This compound is known to exhibit:

  • Moderate solubility in organic solvents: It is generally soluble in non-polar and slightly polar organic solvents, which can facilitate its use in organic synthesis.
  • Limited solubility in water: The presence of a large hydrophobic naphthyl group contributes to its decreased affinity for polar solvents, making it less soluble in water.
  • Enhanced solubility in acidic conditions: The carboxylic acid group may enhance solubility in acidic environments by protonation, which reduces intermolecular interactions.

Understanding the solubility characteristics of this compound not only aids in its effective application in pharmaceuticals but also suggests important considerations for its formulation and stability.

As a general note, the solubility of compounds can be influenced by various factors including temperature, pH, and the presence of salts, which can either increase or decrease the solubility depending on the environmental conditions.

Interesting facts

Interesting Facts about 5-(dimethylamino)-2-ethyl-2-(1-naphthyl)pentanoic acid

5-(Dimethylamino)-2-ethyl-2-(1-naphthyl)pentanoic acid is a fascinating compound that has garnered attention in the fields of medicinal and synthetic chemistry. Here are some interesting insights about this compound:

  • Pharmacological Importance: This compound is often studied for its potential applications as a pharmaceutical agent, particularly in the development of drugs targeting neurological conditions.
  • Structural Uniqueness: Its unique structure, characterized by the presence of a dimethylamino group and a naphthyl ring, allows it to exhibit specific interactions with biological receptors.
  • Synthesis Challenges: The synthesis of this compound may involve several steps, highlighting the challenges chemists face when working with multi-functionalized organic molecules.
  • Research Potential: Ongoing studies on this compound aim to explore its efficacy and mechanism of action in drug development, making it an exciting candidate for further research.
  • Related Compounds: It shares structural similarities with other important compounds in the field, which may lead to insights into structure-activity relationships (SAR) that are crucial for medicinal chemistry.

In summary, the investigation of 5-(dimethylamino)-2-ethyl-2-(1-naphthyl)pentanoic acid continues to be promising, as it stands at the intersection of organic synthesis and pharmacology. Its unique properties and potential applications make it a subject of great interest for chemists and researchers alike.