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5-Ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole

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Identification
Molecular formula
C5H5Cl3N2OS
CAS number
4316-73-8
IUPAC name
5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole
State
State

This compound exists as a solid at room temperature.

Melting point (Celsius)
46.00
Melting point (Kelvin)
319.15
Boiling point (Celsius)
265.00
Boiling point (Kelvin)
538.15
General information
Molecular weight
248.54g/mol
Molar mass
248.5430g/mol
Density
1.5780g/cm3
Appearence

5-Ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole is typically a white to pale yellow solid. It can be characterized by its crystalline structure, and is often odorless or may have a very faint chemical odor.

Comment on solubility

Solubility of 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole

5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole is a compound that exhibits unique solubility characteristics. Its solubility can be influenced by various factors, including the presence of polar and nonpolar groups within its structure.

When considering its solubility:

  • Solubility in Water: This compound is expected to have limited solubility in water due to the presence of the trichloromethyl group, which introduces a significant degree of hydrophobicity.
  • Polar Solvents: It may dissolve better in polar organic solvents such as methanol or ethanol, where the ethoxy group can interact favorably, allowing for enhanced solubility.
  • Impurities: The practical solubility may be affected by the presence of impurities or co-solvents that can enhance or diminish solubility.
  • Temperature Influence: Increasing temperature may also promote better solubility in organic solvents.

In conclusion, while 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole may not be readily soluble in water, it shows potential for solubility in a range of organic solvents, highlighting the importance of solvent choice when dealing with this compound.

Interesting facts

Interesting Facts about 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole

5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole is a fascinating compound that belongs to a class of heterocyclic compounds known as thiadiazoles. This compound exhibits unique properties and reactivity that make it of particular interest in various fields of research. Here are some intriguing facts about this compound:

  • Biological Activity: Thiadiazoles are often known for their biological activities, including antibacterial, antifungal, and anti-inflammatory properties. The incorporation of the ethoxy group and the trichloromethyl substituent can enhance its efficacy in medicinal chemistry.
  • Synthesis: The synthesis of 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole typically involves cyclization reactions of appropriate precursors. This reaction pathway is often of interest to organic chemists looking to explore novel synthetic methods.
  • Applications: Compounds like 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole can find applications in agrochemicals as pesticides or herbicides, showcasing the compound's usefulness in agriculture.
  • Environmental Considerations: Given the chlorinated nature of its structure, it is vital to investigate the environmental impact of using this compound, particularly its degradation and potential toxicity.
  • Structure-Activity Relationship (SAR): The specific substitution patterns on the thiadiazole ring can lead to varied biological activities. Understanding these patterns can help researchers design more effective compounds.

In conclusion, 5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole is more than just a chemical compound; it represents a gateway for exploring complex chemical behavior and potential applications in medicinal and agricultural chemistry. As research continues, compounds like this could pave the way for new discoveries in various scientific disciplines.

Synonyms
Etridiazole
2593-15-9
Echlomezole
Etridiazol
TERRAZOLE
Terrachlor-super X
1,2,4-Thiadiazole, 5-ethoxy-3-(trichloromethyl)-
5-Ethoxy-3-trichloromethyl-1,2,4-thiadiazole
Sanyard
3-(Trichloromethyl)-5-ethoxy-1,2,4-thiadiazole
Caswell No. 428
Etridiazole [BSI:ISO]
Etridiazole [ISO]
etridazole
MF-344
NSC 524929
HSDB 1709
EINECS 219-991-8
5-Aethoxy-3-trichlormethyl-1,2,4-thiadiazol
EPA Pesticide Chemical Code 084701
BRN 1074817
DTXSID3032547
CHEBI:81761
AI3-29280
Ethyl 3-trichloromethyl-1,2,4-thiadiazol-5-yl ether
UNII-9F8237I875
ETRIDIAZOLE [HSDB]
NSC-524929
5-Aethoxy-3-trichlormethyl-1,2,4-thiadiazol [German]
DTXCID1012547
OM-2424
5-Ethoxy-3-trichloromethyl-1,2,4-thiadiazol
5-AETHOXY-3-TRICHLORMETHYL-1,2,4-THIADIAZOL (GERMAN)
TerrachlorSuper X
MF344
5Aethoxy3trichlormethyl1,2,4thiadiazol
5Ethoxy3trichloromethyl1,2,4thiadiazole
USEPA/OPP Pesticide Code: 084701
3(Trichloromethyl)5ethoxy1,2,4thiadiazole
1,2,4Thiadiazole, 5ethoxy3(trichloromethyl)
Ethyl 3trichloromethyl1,2,4thiadiazol5yl ether
Ethyl 3-(trichloromethyl)-1,2,4-thiadiazol-5-yl ether
ethazole
kqtvwcsonpjjpe-uhfffaoysa-n
Ethazol
5-Ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole
Echlomezol
Koban
Planvate
Terracoat
Aaterra
Banrot
Pansoil
Truban
Etcmtb
Terracoat L21
Terraflo
Dwell
Olin mathieson 2,424
ETMT
Ethazole (fungicide)
OM 2424
OM 2425
Etridiazole 10 microg/mL in Cyclohexane
9F8237I875
SCHEMBL20227
Etridiazole, analytical standard
CHEMBL3183350
WLN: T5NS DNJ CO2 EXGGG
Tox21_300924
NSC524929
AKOS015898229
NCGC00163854-01
NCGC00163854-02
NCGC00163854-03
NCGC00254826-01
BP-10210
CAS-2593-15-9
5-Aethoxy-3-trichlormethyl-1,4-thiadiazol
DB-046794
NS00007073
3-(Trichloromethyl)-5-ethoxy-1,4-thiadiazole
3-trichloromethyl-5-ethoxy-1,2,4-thiadiazole
5-Ethoxy-3-(trichloromethyl)-1,4-thiadiazole
C18460
Etridiazole, PESTANAL(R), analytical standard
1,4-Thiadiazole, 5-ethoxy-3-(trichloromethyl)-
Q1371667
Ethyl 3-(trichloromethyl)-1,2,4-thiadiazol-5-yl ether #