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Mephobarbital

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Identification
Molecular formula
C13H18N2O4
CAS number
115-38-8
IUPAC name
5-ethyl-1,3-bis(methoxymethyl)-5-phenyl-hexahydropyrimidine-2,4,6-trione
State
State

Mephobarbital is in a solid state at room temperature, typically found in crystalline powder form.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
364.90
Boiling point (Kelvin)
638.05
General information
Molecular weight
260.30g/mol
Molar mass
260.3030g/mol
Density
1.2700g/cm3
Appearence

Mephobarbital appears as a white, crystalline, or powdery compound. It is often odorless or may possess a slight odor that is characteristic of many barbiturates. The compound is stable under usual conditions and should be stored away from light and moisture to maintain its quality.

Comment on solubility

Solubility Overview

The compound 5-ethyl-1,3-bis(methoxymethyl)-5-phenyl-hexahydropyrimidine-2,4,6-trione exhibits some intriguing solubility characteristics that are worth noting. The solubility of this complex organic molecule can be influenced by various factors such as:

  • Polarity: The presence of multiple methoxymethyl (-OCH3) groups tends to increase the compound's polarity, which may enhance its solubility in polar solvents.
  • Hydrogen Bonding: The -OH groups and nitrogen atoms in the structure can participate in hydrogen bonding, contributing to solubility in polar solvents like water.
  • Hydrophobic Effects: Conversely, the phenyl and ethyl groups may induce hydrophobic interactions, potentially reducing solubility in aqueous environments.

Overall, one can expect that:

  • This compound is likely to be more soluble in organic solvents, such as methanol or ethanol, compared to pure water.
  • Using mixed solvents may enhance solubility by balancing both polar and non-polar interactions.

In conclusion, the complex interplay of functional groups and molecular structure plays a crucial role in determining the solubility behavior of 5-ethyl-1,3-bis(methoxymethyl)-5-phenyl-hexahydropyrimidine-2,4,6-trione, making further studies into its solubility profile particularly interesting.

Interesting facts

Interesting Facts About 5-ethyl-1,3-bis(methoxymethyl)-5-phenyl-hexahydropyrimidine-2,4,6-trione

The compound 5-ethyl-1,3-bis(methoxymethyl)-5-phenyl-hexahydropyrimidine-2,4,6-trione is a fascinating member of the pyrimidine family, known for its varied applications in the fields of medicinal and organic chemistry. Here are some noteworthy aspects:

Key Applications

  • Pharmaceutical Potential: This compound has attracted interest for its potential role in drug development, functioning as a scaffold for various therapeutic agents.
  • Synthetic Intermediates: Its structure allows it to serve as a vital intermediate in the synthesis of more complex molecules used in pharmaceuticals and agrochemicals.
  • Research Interest: Ongoing studies investigate its biochemical activities, particularly in areas related to cell signaling and enzyme inhibition.

Chemical Characteristics

5-ethyl-1,3-bis(methoxymethyl)-5-phenyl-hexahydropyrimidine-2,4,6-trione is characterized by:

  • Versatile Functional Groups: The presence of multiple methoxy groups contributes to its chemical reactivity and makes it susceptible to further functionalization.
  • Hexahydropyrimidine Structure: The unique cyclic structure offers stability and influences the compound's interactions with biological targets.

Scientific Insights

Chemists are continually uncovering the potential of compounds like this one. For example, the study of its reactivity can lead to the development of innovative synthesis routes and advanced materials.

As noted by leading researchers in the field, "Exploring the dimensions of pyrimidines can open doors to new pharmacological discoveries." This reflects the beauty of chemical research, where each compound has the potential to impact various scientific disciplines.

In summary, 5-ethyl-1,3-bis(methoxymethyl)-5-phenyl-hexahydropyrimidine-2,4,6-trione is not just a chemical formula; it represents a gateway to understanding more about molecular design and the intricacies of modern chemistry.

Synonyms
Eterobarb
Eterobarbital
27511-99-5
Eterobarbe
Eterobarbo
Eterobarbum
EX 12-095
RMI 16,238
N,N'-Dimethoxymethylphenobarbital
RMI-16238
5-Ethyl-1,3-bis(methoxymethyl)-5-phenylbarbituric acid
DTXSID9045710
432SI047GA
EX-12-095
DTXCID7025710
enterobarb
RefChem:921191
Antilon
1,3-Bis(methoxymethyl)phenobarbital
1,3-Bis(methoxymethyl)-5-ethyl-5-phenylbarbituric acid
5-Ethyl-1,3-bis(methoxymethyl)-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione
MLS000112274
Barbituric acid, 5-ethyl-1,3-bis(methoxymethyl)-5-phenyl-
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-1,3-bis(methoxymethyl)-5-phenyl-
SMR000108188
BARBITURIC ACID, 1,3-BIS(METHOXYMETHYL)-5-ETHYL-5-PHENYL-
EX 12-095;RMI 16238
5-ethyl-1,3-bis(methoxymethyl)-5-phenyl-1,3-diazinane-2,4,6-trione
5-ethyl-1,3-bis(methoxymethyl)-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione
Eterobarbe [INN-French]
Eterobarbum [INN-Latin]
Eterobarbo [INN-Spanish]
CAS-27511-99-5
BRN 0570278
Eterobarb [USAN:INN:BAN]
UNII-432SI047GA
Antilon (TN)
1,3-Dimethoxymethyl-5-ethyl-5-phenylbarbituric acid
ETEROBARB [INN]
Opera_ID_119
ETEROBARB [MI]
Eterobarb (USAN/INN)
ETEROBARB [USAN]
ETEROBARB [MART.]
Oprea1_077095
Oprea1_172728
SCHEMBL35417
MLS001074303
CHEMBL327407
CHEBI:135366
DACOQFZGGLCXMA-UHFFFAOYSA-N
HMS1586N08
HMS2232A07
Tox21_110991
STK091981
AKOS000650439
Tox21_110991_1
NCGC00075916-01
NCGC00075916-02
NCGC00075916-04
DA-63292
HY-114692
CS-0064100
NS00120912
ST50882181
D04077
SR-01000488843
Q5402802
SR-01000488843-1
BRD-K64834129-001-19-6
1,3-bis(methoxymethyl)-5-ethyl-5-phenyl-1,3,5-trihydropyrimidine-2,4,6-trione