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Mephenytoin

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Identification
Molecular formula
C12H14N2O3
CAS number
50-12-4
IUPAC name
5-ethyl-5-(4-hydroxyphenyl)hexahydropyrimidine-2,4,6-trione
State
State

The compound is in a solid state at room temperature. It is typically stable and does not display volatile properties, making it suitable for storage and handling at ambient conditions.

Melting point (Celsius)
119.50
Melting point (Kelvin)
392.65
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
218.24g/mol
Molar mass
218.2410g/mol
Density
1.3440g/cm3
Appearence

Mephenytoin is a white or off-white solid. It is typically crystalline in structure and does not have any significant color, making it generally appear white in its pure form. There are no distinctive odor or luminescent properties associated with this compound.

Comment on solubility

Solubility of 5-ethyl-5-(4-hydroxyphenyl)hexahydropyrimidine-2,4,6-trione

The solubility of 5-ethyl-5-(4-hydroxyphenyl)hexahydropyrimidine-2,4,6-trione can provide valuable insights into its potential applications and behavior in various environments. Understanding its solubility encompasses several key factors:

  • Polarity: This compound's molecular structure contains both hydrophobic and hydrophilic groups, which can significantly affect its interaction with solvents.
  • Solvent Choice: Common solvents for evaluating solubility include water, ethanol, and dimethyl sulfoxide (DMSO). The choice of solvent can dramatically alter the solubility outcomes.
  • Temperature Effects: Generally, increased temperature enhances solubility due to elevated kinetic energy; however, this varies based on the compound's characteristics.
  • pH Sensitivity: Given the presence of a hydroxy group, the compound's solubility may be pH-dependent, affecting its ionization and solubility in aqueous environments.

Quote: "The solubility behavior of a compound is pivotal in determining its utility across pharmaceuticals, agrochemicals, and materials science." This classic understanding urges researchers to dive into the molecular dynamics to ascertain how 5-ethyl-5-(4-hydroxyphenyl)hexahydropyrimidine-2,4,6-trione behaves under different conditions.

Ultimately, elucidating the solubility of this compound can pave the way for novel applications and innovative uses, driving further research and development in the field.

Interesting facts

Interesting Facts About 5-ethyl-5-(4-hydroxyphenyl)hexahydropyrimidine-2,4,6-trione

5-ethyl-5-(4-hydroxyphenyl)hexahydropyrimidine-2,4,6-trione is a fascinating compound with several noteworthy attributes that make it an interesting subject of study:

  • Chemical Structure: This compound features a hexahydropyrimidine ring, which is characteristic of a class of compounds known for their diverse biological activities. The presence of the ethyl group enhances its lipophilicity, potentially influencing how it interacts with biological membranes.
  • Potential Biological Activity: Compounds related to this structure often show potential for pharmacological applications, particularly as modulators of therapeutic pathways. The presence of the 4-hydroxyphenyl moiety could suggest antioxidant properties, making this compound an interesting candidate for research in medicinal chemistry.
  • Applications in Research: Investigations into derivatives of this compound might focus on their use in drug development. The synthesis of similar pyrimidine derivatives has been shown to yield compounds with significant activity against various diseases, including cancer.
  • Synthesis Pathways: Scientists may employ several synthetic routes to produce this compound, often involving cyclization reactions that showcase creativity in synthetic organic chemistry.

As a compound with a complex structure and potential biological significance, 5-ethyl-5-(4-hydroxyphenyl)hexahydropyrimidine-2,4,6-trione continues to pique the interest of chemists and biochemists alike. Researchers are drawn to its potential applications and the unique challenges it presents in terms of synthesis and characterization.

Synonyms
4-Hydroxyphenobarbital
379-34-0
p-Hydroxyphenobarbital
4-Hydroxy Phenobarbital
p-Hydroxyphenobarbitone
Hydroxyphenobarbitone,p-
RF9R6T1NUN
P-hydroxy-PB
5-ethyl-5-(4-hydroxyphenyl)-1,3-diazinane-2,4,6-trione
NSC 159266
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(4-hydroxyphenyl)-
Phenobarbital-p-hydroxy
P-hydroxy-phenobarbitone
Para-hydroxyphenobarbital
EINECS 206-831-7
UNII-RF9R6T1NUN
HYDROXYPHENOBARBITAL
NSC-159266
5-Ethyl-5-(4'-hydroxyphenyl)barbituric acid monohydrate
5-Ethyl-5-(p-hydroxy-phenyl)barbituric acid
5-Ethyl-5-(4-hydroxyphenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
DTXSID20191328
5-ETHYL-5-(P-HYDROXYPHENYL)BARBITURIC ACID
5-(P-HYDROXYPHENYL)-5-ETHYLBARBITURIC ACID
5-ETHYL-5-(4-HYDROXYPHENYL)BARBITURIC ACID
BARBITURIC ACID, 5-ETHYL-5-(P-HYDROXYPHENYL)-
4-Hydroxy Phenobarbital (1.0mg/ml in Acetonitrile)
CHEMBL1908024
DTXCID30113819
CHEBI:180569
NSC159266
AKOS030255840
NS00030314
5-ethyl-5-(p-hydroxy-phenyl)-barbituric acid
5-Ethyl-5-(4-hydroxyphenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione #