Skip to main content

Amobarbital

ADVERTISEMENT
Identification
Molecular formula
C11H18N2O3
CAS number
57-43-2
IUPAC name
5-ethyl-5-hexyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, amobarbital is found in a solid state, typically in the form of a crystalline powder.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
226.28g/mol
Molar mass
226.2790g/mol
Density
1.1443g/cm3
Appearence

Amobarbital usually appears as a white, crystalline powder. It may also be available in granules or a pressed solid form, generally used in pharmaceutical settings. The powder is typically odorless but may have a slightly bitter taste.

Comment on solubility

Solubility of 5-ethyl-5-hexyl-hexahydropyrimidine-2,4,6-trione

The solubility of 5-ethyl-5-hexyl-hexahydropyrimidine-2,4,6-trione in various solvents can be influenced by several factors. Understanding its solubility properties is essential for applications in pharmaceuticals and organic chemistry.

Factors Influencing Solubility:

  • Polarity: This compound's structure includes both hydrophobic and hydrophilic regions, which may lead to varying degrees of solubility in polar and non-polar solvents.
  • Temperature: Increased temperature typically enhances solubility, so this compound may show improved solubility in hot solvents.
  • pH Levels: The solution's pH can significantly affect the ionization of functional groups, stabilizing various ionic forms of the compound.

Although specific experimental data for solubility may be limited, it is common for compounds of this class to exhibit moderate to low solubility in water, while showing higher solubility in organic solvents such as dichloromethane or ethanol.
To illustrate the solubility behavior:

Typical Solvent Categories:

  • Water: Low solubility
  • Alcohols: Moderate to good solubility
  • Haloalkanes: Generally better solubility

Understanding these solubility characteristics is vital for effective use in practical applications, allowing researchers to select the appropriate solvent for desired chemical reactions or formulations.

Interesting facts

Interesting Facts About 5-Ethyl-5-hexyl-hexahydropyrimidine-2,4,6-trione

The compound 5-ethyl-5-hexyl-hexahydropyrimidine-2,4,6-trione is a fascinating example of a pyrimidine derivative, known for its complex structure and potential applications in various fields. Here are some intriguing aspects about this compound:

  • Structural Composition: This compound belongs to the class of hexahydropyrimidines, which are heterocyclic compounds containing nitrogen atoms in the ring structure. The presence of ethyl and hexyl groups contributes to its diverse chemical properties.
  • Biological Significance: Pyrimidine derivatives play crucial roles in biology, particularly in the synthesis of nucleic acids, such as DNA and RNA. This connection to genetic material makes compounds like this one of keen interest in biochemical research.
  • Potential Applications: Compounds similar to 5-ethyl-5-hexyl-hexahydropyrimidine-2,4,6-trione are being explored for their potential as pharmaceuticals, particularly in the development of anti-cancer and anti-viral agents. Their varied substituents can influence biological activity.
  • Reactivity and Chemistry: The positions of the keto groups (carbonyls) at the 2, 4, and 6 positions can significantly affect the reactivity of this compound. Understanding the mechanisms behind its reactivity can lead to new synthetic pathways for creating vinyl-based polymers and other useful materials.
  • Synthesis: The synthesis of hexahydropyrimidine-2,4,6-triones is typically achieved through a variety of methods, including cyclization reactions. This highlights the versatility of organic synthesis techniques in producing complex compounds with specific functional groups.

As a chemistry student or scientist, exploring compounds like 5-ethyl-5-hexyl-hexahydropyrimidine-2,4,6-trione can immensely broaden your understanding of organic chemistry and its applications in real-world scenarios. The intricate balance between structure and function in such compounds exemplifies the beauty of chemistry.

Synonyms
Ortal
HEXETHAL
77-30-5
5-Ethyl-5-hexylbarbituric acid
Barbituric acid, 5-ethyl-5-hexyl-
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-hexyl-
Acide hexylethylbarbiturique
NSC 32303
62AYA1LUDJ
5-Ethyl-5-hexyl-2,4,6(1H,3H,5H)-pyrimidinetrione
NSC-32303
Hexethal (VAN)
Ortol (VAN)
UNII-62AYA1LUDJ
Acide hexylethylbarbiturique [French]
5-ethyl-5-hexyl-1,3-diazinane-2,4,6-trione
Athyl-n-hexylbarbitursaure
SCHEMBL712742
2,4,6(1H,3H,5H)-Pyrimidinetrione,5-ethyl-5-hexyl-
CHEMBL1797004
DTXSID20871618
DTXSID30227809
PSTVHRSUNBSVIJ-UHFFFAOYSA-N
WLN: T6VMVMV FHJ F6 F2
EX-A5403
NSC32303
Barbituric acid, 5-ethyl-5-n-hexyl-
5-HEXYL-5-ETHYLBARBITURIC ACID
Hexethal (5-ethyl-5-hexylbarbituric acid)
NS00114036
2,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-hexyl-
Q27887323
5-Ethyl-5-hexyl-2-hydroxypyrimidine-4,6(1H,5H)-dione
pyrimidine-2,4,6(1H,3H,5H)-trione, 5-ethyl-5-hexyl-