Interesting facts
Interesting Facts about 5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid is an intriguing compound that belongs to the quinoline family, a class of compounds often noted for their diverse biological activities. Here are some fascinating aspects of this compound:
- Quinoline Backbone: The compound features a quinoline structure, which is a heterocyclic aromatic organic compound. Quinoline derivatives are widely recognized for their roles in pharmaceuticals and agrochemicals.
- Biological Significance: Compounds related to quinolines have been shown to exhibit various pharmacological properties. For instance, they may possess antimicrobial, antimalarial, and anticancer activities, making them valuable in medicinal chemistry.
- Unique Functional Groups: With both dioxolo and carboxylic acid functional groups, this compound is a prime example of how combining different functionalities can lead to enhanced biological activity or specificity. The presence of these groups can influence reactivity and solubility.
- Synthetic Routes: The synthesis of this compound often involves multi-step organic reactions. Understanding the synthetic pathways can provide insight into the methodology of constructing complex organic molecules.
- Potential Applications: Researchers are continually exploring the potential applications of quinoline derivatives like this one. They may lead to the development of novel drugs, particularly in the fight against resistant pathogens.
This compound's intricate structure and diverse functionality make it a subject of interest for both synthetic chemists and biologists alike. As stated by famous chemist Robert H. Grubbs, "Chemistry is the study of transformation," and compounds like 5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid embody just that through their potential transformations into life-saving drugs.
Synonyms
oxolinic acid
14698-29-4
Nidantin
Utibid
Dioxacin
Emyrenil
Prodoxal
Prodoxol
Oxolinic
Oksaren
Ossian
Uroxol
Acido oxolinico
Acide oxolinique
Gramurin
Starner
Ultibid
Oxoboi
Pietil
Uro-alvar
Acidum oxolinicum
Cistopax
Orthurine
Tiurasin
Uritrate
Urotrate
Acido ossolico
NSC-110364
Aqualinic
Urinox
5-Ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
W 4565
5-Ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
1-Ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylic acid
MFCD00056775
5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
CCRIS 6301
NSC 110364
Oxolinic acid impurity B
HSDB 3243
EINECS 238-750-8
UNII-L0A22B22FT
1-Ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid
5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinoline-7-carboxylic acid
BRN 0620635
Acide oxolinique [INN-French]
Acido oxolinico [INN-Spanish]
Acidum oxolinicum [INN-Latin]
L0A22B22FT
DTXSID1021089
Acid, Oxolinic
CHEBI:138856
1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo-
NSC110364
S-0208
DTXCID101089
W-4565
1,3-Dioxolo[4,5-g]quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo-
16172-03-5
NCGC00015762-06
CAS-14698-29-4
5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid
5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid
OXOLINIC ACID (MART.)
OXOLINIC ACID [MART.]
Acide oxolinique (INN-French)
Acido oxolinico (INN-Spanish)
Acidum oxolinicum (INN-Latin)
Acido ossolico [DCIT]
OXOLINIC ACID (EP MONOGRAPH)
OXOLINIC ACID [EP MONOGRAPH]
5-ETHYL-5,8-DIHYDRO-8-OXO(1,3)DIOXOLO(4,5-G)QUINOLINE-7-CARBOXYLIC ACID
SR-01000076042
Inoxyl
oxolinic-acid
5-ethyl-8-oxo-5,8-dihydro(1,3)dioxolo(4,5-g)quinoline-7-carboxylic acid
Oxolinic acid [USAN:INN:BAN]
Aqualinic (TN)
quinolone antibiotic
Prestwick_629
Spectrum_001397
Prestwick0_000193
Prestwick1_000193
Prestwick2_000193
Prestwick3_000193
Spectrum2_000933
Spectrum3_001490
Spectrum4_000073
Spectrum5_001176
Lopac-O-0877
Oxolinic acid (Standard)
OXOLINIC ACID [MI]
Oxolinic acid (USAN/INN)
OXOLINIC ACID [INN]
Lopac0_000952
Oprea1_169598
SCHEMBL24445
BSPBio_000145
BSPBio_003079
KBioGR_000625
KBioSS_001877
OXOLINIC ACID [HSDB]
OXOLINIC ACID [USAN]
MLS000028501
DivK1c_000659
SPECTRUM1502030
SPBio_000866
SPBio_002066
BPBio1_000161
CHEMBL416755
OXOLINIC ACID [WHO-DD]
GTPL12999
HMS502A21
HY-B1002R
KBio1_000659
KBio2_001877
KBio2_004445
KBio2_007013
KBio3_002579
J01MB05
NINDS_000659
HMS1568H07
HMS1921F12
HMS2092P09
HMS2095H07
HMS3262P06
HMS3712H07
Oxolinic acid, analytical standard
Pharmakon1600-01502030
Oxolinic acid, quinolone antibiotic
HY-B1002
Tox21_110216
Tox21_202787
Tox21_500952
AC8065
BBL009934
CCG-39666
NSC758177
s4537
STK801351
5-ethyl-8-oxo-5-hydro-2H-1,3-dioxoleno[4,5-g]quinoline-7-carboxylic acid
AKOS000282622
Tox21_110216_1
CS-4499
DB13627
LP00952
NSC-758177
SDCCGSBI-0050926.P004
IDI1_000659
NCGC00015762-01
NCGC00015762-02
NCGC00015762-03
NCGC00015762-04
NCGC00015762-05
NCGC00015762-07
NCGC00015762-08
NCGC00015762-09
NCGC00015762-10
NCGC00015762-11
NCGC00015762-13
NCGC00015762-17
NCGC00093361-02
NCGC00093361-03
NCGC00093361-04
NCGC00093361-05
NCGC00260333-01
NCGC00261637-01
AS-12087
SMR000058314
SY066716
SBI-0050926.P003
DB-042865
EU-0100952
NS00010598
VU0243182-3
D02301
O 0877
WLN: T C566 DO FO JN MV EHJ J2 LVQ
Q287840
SR-01000076042-1
SR-01000076042-4
SR-01000076042-6
BRD-K73394555-001-08-6
BRD-K73394555-237-01-1
5-Ethyl-5,3-dioxolo[4,5-g]quinoline-7-carboxylic acid
F3351-0487
1-Ethyl-1,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid
Oxolinic acid, European Pharmacopoeia (EP) Reference Standard
1,5-g]quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo-
1.4-Dihydro-1-ethyl-6,7-methylenedioxy-4-oxoquinoline-3-carboxylic acid
5-ETHYL-8-OXO-2H,5H,8H-[1,3]DIOXOLO[4,5-G]QUINOLINE-7-CARBOXYLIC ACID
5-Ethyl-8-oxo-5,8-dihydro (1,3) dioxolo (4,5-g) quinoline-7-carboxylic acid
5-Ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid #
W-4565; 5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid
238-750-8
InChI=1/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17
Solubility of 5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
The solubility of 5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid (C14H9NO5) can be influenced by several factors. Understanding how this compound interacts with solvents provides insight into its behavior in diverse chemical environments.
Factors Affecting Solubility
In general, it is expected that this compound will demonstrate limited solubility in non-polar solvents, while potentially showing better solubility in polar solvents due to the presence of the carboxylic acid group. Experiments may yield specific solubility data, but care should be taken to consider the solvent used.
Conclusion
To summarize, the solubility of 5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid is likely to be influenced significantly by its molecular structure and the nature of the solvent, thus making it an intriguing subject for further study.