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Barbital

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Identification
Molecular formula
C8H12N2O3
CAS number
57-44-3
IUPAC name
5-ethylhexahydropyrimidine-2,4,6-trione
State
State

Solid at room temperature. It is typically handled as a powder.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
184.19g/mol
Molar mass
184.1900g/mol
Density
1.1000g/cm3
Appearence

Barbital is a white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 5-ethylhexahydropyrimidine-2,4,6-trione

The solubility of 5-ethylhexahydropyrimidine-2,4,6-trione can be an intriguing subject due to its unique structural characteristics. As with many organic compounds, solubility is influenced by a variety of factors including:

  • Polarity: The presence of functional groups that exhibit polar characteristics can enhance the solubility of this compound in polar solvents like water.
  • Hydrogen Bonding: The ability of 5-ethylhexahydropyrimidine-2,4,6-trione to form hydrogen bonds plays a critical role in its solubility profile.
  • Molecular Size: Larger molecules may experience reduced solubility due to steric hindrance, which makes interactions with solvent molecules less favorable.

In general, compounds that are more polar and can engage in hydrogen bonding tend to be more soluble in water, while less polar compounds are often better dissolved in organic solvents. This compels us to consider:

  • Whether 5-ethylhexahydropyrimidine-2,4,6-trione is more soluble in water or organic solvents
  • The presence of any substituents that could affect its solubility behavior

Ultimately, solubility assessments in different solvents will provide insights into the practical applications of this compound. As with many substances, it’s essential to carry out empirical tests to fully understand its solubility characteristics.

Interesting facts

Exploring 5-Ethylhexahydropyrimidine-2,4,6-trione

5-Ethylhexahydropyrimidine-2,4,6-trione is a fascinating compound that showcases the complexity and creativity of organic chemistry. This molecule is part of the pyrimidine family, which is significant in biochemistry due to its presence in nucleic acids. Here are some interesting facts about this intriguing compound:

  • Diverse Applications: Compounds like 5-ethylhexahydropyrimidine-2,4,6-trione are valuable in various fields, including pharmaceuticals and agriculture. They may serve as intermediates in the synthesis of biologically active molecules, particularly those resembling nucleotides.
  • Biological Relevance: Pyrimidine derivatives play critical roles in cellular processes, including the formation of RNA and DNA. Studying this particular trione may lead to insights into metabolic pathways or mechanism of action of other pyrimidines.
  • Spectroscopic Studies: This compound presents an excellent opportunity for spectroscopic analysis. Techniques such as NMR and IR spectroscopy are pivotal for understanding the molecular structure and dynamics, thereby enriching the knowledge of its behavior in solution.
  • Chirality and Isomerism: The stereochemistry inherent in compounds with multiple chiral centers, like 5-ethylhexahydropyrimidine-2,4,6-trione, can lead to the formation of numerous isomers. This aspect is crucial, as different isomers may exhibit varying biological activities or reactivities.
  • Designing New Compounds: Researchers often derive inspiration from existing compounds. The structural components of 5-ethylhexahydropyrimidine-2,4,6-trione could serve as a scaffold for developing new compounds with enhanced properties, such as improved efficacy or reduced side effects.

In conclusion, 5-ethylhexahydropyrimidine-2,4,6-trione exemplifies the intricate nature of organic compounds, and its study could yield exciting advancements in both synthetic chemistry and biochemistry. Within the broader context of research, it exemplifies how a single molecule can open doors to a multitude of scientific inquiries and applications.

Synonyms
5-ETHYLBARBITURIC ACID
Barbituric acid, 5-ethyl-
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-
DX33TC4GHM
5-ethyl-2,4,6(1h,3h,5h)-pyrimidinetrione
EINECS 219-743-9
NSC-27274
NSC-66908
DTXSID90179850
NSC 27274
NSC 66908
DTXCID50102341
219-743-9
2518-72-1
5-ethyl-1,3-diazinane-2,4,6-trione
2,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-
ethylbarbituric acid
5-Ethylbarbituric Acid; NSC 27274; NSC 66908; 5-Ethyl-2,4,6(1H,3H,5H)pyrimidinetrione;
NSC66908
UNII-DX33TC4GHM
SCHEMBL145905
NSC27274
AKOS006273877
NS00027831
VU0422109-2
G47023
F9995-0213