Interesting facts
Interesting Facts about 5-Fluoro-N-hexyl-2,4-dioxo-pyrimidine-1-carboxamide
5-Fluoro-N-hexyl-2,4-dioxo-pyrimidine-1-carboxamide is a captivating compound that belongs to the family of pyrimidine derivatives, which are known for their significant biological activities. Here are some fascinating aspects of this compound:
- Pharmacological Potential: Compounds containing the pyrimidine nucleus have been extensively studied for their potential as therapeutic agents. This particular compound might exhibit interesting physiological effects due to the presence of fluorine, which can enhance biological activity.
- Fluorinated Compounds: The introduction of fluorine atoms into organic compounds often alters their pharmacokinetic properties. This can lead to increased metabolic stability and improved target interaction.
- Structure-Activity Relationship (SAR): Understanding how substituents on the pyrimidine ring affect biological activity is a key area of research. The hexyl group in this compound adds lipophilicity, potentially enhancing membrane permeability.
- Applications in Medicine: Pyrimidines are essential in the synthesis of nucleic acids. Thus, compounds like 5-fluoro-N-hexyl-2,4-dioxo-pyrimidine-1-carboxamide can serve as building blocks for antiviral or anticancer agents.
In summary, the unique combination of structural features in 5-fluoro-N-hexyl-2,4-dioxo-pyrimidine-1-carboxamide opens up numerous possibilities for research and development in medicinal chemistry. As scientists continue to explore the vast potential of pyrimidine derivatives, compounds like this serve as an excellent platform for innovations in drug design.
Synonyms
carmofur
61422-45-5
Mifurol
HCFU
Yamaful
1-Hexylcarbamoyl-5-fluorouracil
Carmofurum
Carmofur [INN:JAN]
Carmofurum [INN-Latin]
1(2H)-Pyrimidinecarboxamide, 5-fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-
Mifurol (TN)
CCRIS 2759
Uracil, 5-fluoro-1-hexylcarbamoyl-
HA82M3RAB2
NSC-758963
BRN 0888898
DTXSID2045941
5-fluoro-N-hexyl-2,4-dioxo-3,4-dihydropyrimidine-1(2H)-carboxamide
CARMOFUR [INN]
CARMOFUR [JAN]
CARMOFUR [MI]
CARMOFUR [MART.]
CARMOFUR [WHO-DD]
5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
5-Fluoro-1-hexylcarbamoyluracil
DTXCID0025941
5-Fluoro-1-(hexylcarbamoyl)uracil
1-Pyrimidinecarboxamide, 1,2,3,4-tetrahydro-2,4-dioxo-5-fluoro-N-hexyl-
2,4-Dioxo-5-fluoro-N-hexyl-1,2,3,4-tetrahydro-1-pyrimidinecarboxamide
2,4-Dioxo-5-fluoro-N-hexyl-3,4-dihydro-1(2H)-pyrimidinecarboxamidme
5-24-06-00277 (Beilstein Handbook Reference)
NSC 758963
1-(n-hexylcarbamoyl)-5-fluorouracil
NCGC00095165-01
Carmofurum (INN-Latin)
1(2H)-Pyrimidinecarboxamide, 3,4-dihydro-2,4-dioxo-5-fluoro-N-hexyl-
CARMOFUR (MART.)
C11H16FN3O3
Hexylcarbamoyl fluorouracil
SMR000466363
CAS-61422-45-5
UNII-HA82M3RAB2
Carmofure
Yamafur
N-hexylcarbamoyl-5-fluorouracil
HCFU; Mifurol
Carmofur,(S)
5-fluoro-1-(n-hexylcarbamoyl)uracil
Carmofur (Standard)
MFCD00866284
CPD000466363
Spectrum2_000026
Spectrum3_001960
Carmofur (JP17/INN)
5-Fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinecarboxamide
SCHEMBL8037
BSPBio_003560
Carmofur - Bio-X trade mark
MLS000759482
MLS000759483
MLS001423992
SPECTRUM1505317
SPBio_000091
CHEMBL460499
CHEBI:31360
HY-B0182R
KBio3_002882
L01BC04
GLXC-15145
HMS1922D08
HMS2051G12
HMS3393G12
HMS3654F13
HMS3712P11
Pharmakon1600-01505317
BCP21373
HY-B0182
Tox21_111464
BDBM50431275
CCG-39700
NSC758963
s1289
Carmofur, >=98% (HPLC), powder
5-Fluoro-1-(hexylaminocarbonyl)uracil
AKOS015906778
Tox21_111464_1
CS-2064
DB09010
FC60423
NC00116
NCGC00095165-02
NCGC00095165-03
NCGC00095165-04
NCGC00095165-05
NCGC00095165-07
NCGC00095165-16
NCGC00177991-01
AC-12465
BC164286
BS-17210
SBI-0207040.P001
DB-053879
C2663
NS00068612
SW197496-2
C75879
D01784
AB00698319-04
AB00698319_06
AB00698319_07
A833212
SR-01000763370
5-fluoro-N-hexyl-2,4-dioxo-1-pyrimidinecarboxamide
Q5043732
SR-01000763370-3
BRD-K11630072-001-06-6
BRD-K11630072-001-11-6
BRD-K11630072-001-12-4
BRD-K11630072-001-13-2
5-fluoranyl-N-hexyl-2,4-bis(oxidanylidene)pyrimidine-1-carboxamide
5-fluoro-N-hexyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-1-carboxamide
689-431-9
Solubility of 5-fluoro-N-hexyl-2,4-dioxo-pyrimidine-1-carboxamide
The solubility of 5-fluoro-N-hexyl-2,4-dioxo-pyrimidine-1-carboxamide (C11H14FN3O3) can be influenced by several factors, making it a fascinating compound to consider in that regard. Here are some key points about its solubility:
In conclusion, while the solubility of 5-fluoro-N-hexyl-2,4-dioxo-pyrimidine-1-carboxamide is complex, understanding the balance between its hydrophilic and hydrophobic properties allows for informed predictions on its behavior in different environments. As the saying goes, “Like dissolves like,” making the choice of solvent critical for achieving desired solubility.