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Olanzapine

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Identification
Molecular formula
C17H20ClN3S
CAS number
132539-06-1
IUPAC name
(5-hydroxy-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)ammonium;chloride
State
State

At room temperature, olanzapine is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
353.15
Boiling point (Kelvin)
626.30
General information
Molecular weight
312.44g/mol
Molar mass
312.4410g/mol
Density
1.2000g/cm3
Appearence

Olanzapine appears as an off-white to yellow crystalline powder. It is practically insoluble in water, sparingly soluble in methanol, and slightly soluble in ethanol and ethyl acetate.

Comment on solubility

Solubility Considerations for (5-hydroxy-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)ammonium;chloride

The solubility of (5-hydroxy-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)ammonium;chloride can be influenced by several factors, mainly due to its ionic nature and the structural characteristics of the compound. Understanding solubility is critical for applications in pharmaceuticals and chemical formulations.

Key Factors Affecting Solubility:

  • Polarity: The presence of ammonium and chloride ions suggests that this compound is likely to be polar, promoting solubility in polar solvents such as water.
  • pH Sensitivity: The solubility may vary with pH, as the hydroxyl group could participate in various interactions that can enhance or hinder its dissolution.
  • Temperature: Typically, an increase in temperature could lead to improved solubility for many salts and ions, including this compound.
  • Hydrogen Bonding: The hydroxyl group may engage in hydrogen bonding with water molecules, facilitating solubility.

In conclusion, due to its ionic structure and polar characteristics, (5-hydroxy-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)ammonium;chloride is expected to exhibit considerable solubility in water, especially under varying environmental conditions. The interplay of polarity, interceptive temperature changes, and potential hydrogen bonding mechanisms all contribute to its solubility profile.

Interesting facts

Interesting Facts about (5-hydroxy-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)ammonium chloride

This unique compound is a fascinating example of a complex organic molecule that showcases the interplay between aromatic systems and functional groups. It belongs to a class of compounds known for their diverse applications in medicinal chemistry and pharmacology.

Key Features

  • Functionality: The presence of both hydroxy and ammonium groups makes this compound particularly interesting in terms of its reactivity and potential interactions with biological systems.
  • Structural Complexity: Its intricate structure not only highlights the beauty of chemical architecture but also suggests various pathways for functions and reactions.
  • Potential Applications: Compounds like this are often studied for their roles in drug development, especially in targeting specific biological pathways or receptors.

As a fascinating part of the chemical landscape, the study of (5-hydroxy-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)ammonium chloride can reveal deeper insights into molecular behavior and the design of new therapeutic agents. It serves as a reminder of the incredible diversity found within chemical compounds and the endless possibilities they offer for innovation in scientific research.

Quote to Reflect On

As Robert H. Grubbs once said, "The intersection of chemistry and biology is where the real magic happens." This compound is a prime example of that magic in the field of medicinal chemistry.

Synonyms
10,11-Dihydro-11-aminodibenzo(b,f)thiepin-10-ol hydrochloride hydrate
16946-57-9
11-Amino-10,11-dihydrodibenzo(b,f)thiepin-10-ol hydrochloride monohydrate
DIBENZO(b,f)THIEPIN-10-OL, 10,11-DIHYDRO-11-AMINO-, HYDROCHLORIDE, HYDRATE