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Fosamprenavir

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Identification
Molecular formula
C25H36N3O9P
CAS number
226700-79-4
IUPAC name
[5-hydroxy-6-methyl-4-[[(3-oxoisoxazolidin-4-yl)amino]methyl]-3-pyridyl]methyl dihydrogen phosphate
State
State

At room temperature, Fosamprenavir is in a solid state.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
585.65g/mol
Molar mass
585.6530g/mol
Density
1.6000g/cm3
Appearence

Fosamprenavir is typically a white to off-white powder. It may also appear in a crystalline form, and as a pharmaceutical drug, it is often pressed into tablets or capsules with additional inactive ingredients.

Comment on solubility

Solubility of 5-hydroxy-6-methyl-4-[[(3-oxoisoxazolidin-4-yl)amino]methyl]-3-pyridyl]methyl dihydrogen phosphate

The solubility of a compound plays a crucial role in determining its behavior in various chemical processes. For 5-hydroxy-6-methyl-4-[[(3-oxoisoxazolidin-4-yl)amino]methyl]-3-pyridyl]methyl dihydrogen phosphate (C25H36N3O9P), one can anticipate varying degrees of solubility based on its intricate structure, which incorporates hydrophilic and hydrophobic components.

Factors Influencing Solubility:

  • Polar Functional Groups: The presence of phosphate groups (PO₄) often enhances solubility in water.
  • Hydrogen Bonding: The hydroxyl group (–OH) can participate in hydrogen bonding, which may further improve solvation in aqueous solutions.
  • Molecular Weight: With a relatively high molecular weight, there could be challenges regarding dissolution compared to smaller compounds.
  • pH Dependency: The solubility may vary significantly with pH due to protonation or deprotonation of functional groups.

In summary, while 5-hydroxy-6-methyl-4-[[(3-oxoisoxazolidin-4-yl)amino]methyl]-3-pyridyl]methyl dihydrogen phosphate is expected to be soluble in polar solvents, particularly water, the exact solubility will depend on external factors such as temperature and the solvent's properties. It's recommended to conduct empirical solubility tests to obtain precise data.

Interesting facts

Interesting Facts about 5-Hydroxy-6-Methyl-4-[[[3-Oxoisoxazolidin-4-Yl]Amino]Methyl]-3-Pyridyl]Methyl Dihydrogen Phosphate

The compound 5-hydroxy-6-methyl-4-[[[3-oxoisoxazolidin-4-yl]amino]methyl]-3-pyridyl]methyl dihydrogen phosphate is a fascinating molecule with diverse implications in scientific research and potential application arenas. Here are some compelling aspects about this compound:

  • Biological Relevance: This compound's structure indicates it may play a significant role in various biological processes, particularly due to the presence of the pyridine ring and the phosphate moiety. The pyridine ring is often implicated in interactions with enzymes and receptors.
  • Pharmacological Potential: The unique combination of functional groups suggests potential use in pharmaceutical applications, particularly as a lead compound for the development of new therapeutic agents.
  • Structure-Activity Relationship: The compound's intricate design encourages studies into its structure-activity relationship. Modifications could lead to enhanced efficacy or reduced side effects in drug candidates.
  • Applications in Coordination Chemistry: The presence of nitrogen atoms may allow this compound to act as a ligand in coordination chemistry, facilitating the development of metal-complexes with novel properties.
  • Research Significance: Due to its complex structure, this compound serves as an excellent subject for advanced spectroscopic studies, aiding in the understanding of molecular behavior and interaction patterns.

As a chemist delving into the nuances of this compound, one must appreciate the interplay of its functional groups and the potential repercussions of small structural changes. In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." Exploring such complex molecules certainly opens the door to new vistas of discovery!

Synonyms
LCS
PD042789