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7-Methyljuglone

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Identification
Molecular formula
C11H8O3
CAS number
481-39-0
IUPAC name
5-hydroxy-7-methyl-naphthalene-1,4-dione
State
State

At room temperature, 7-Methyljuglone is a solid. It retains its crystalline form under standard conditions.

Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
342.78
Boiling point (Kelvin)
615.93
General information
Molecular weight
188.19g/mol
Molar mass
188.1890g/mol
Density
1.3154g/cm3
Appearence

7-Methyljuglone is a yellow to orange colored crystalline solid. It tends to form needle-like crystals and exhibits a characteristic hue that distinguishes it visually.

Comment on solubility

Solubility of 5-hydroxy-7-methyl-naphthalene-1,4-dione

5-hydroxy-7-methyl-naphthalene-1,4-dione, also known as TMN, exhibits unique solubility characteristics that are influenced by its chemical structure. Understanding its solubility is essential for applications in organic synthesis and medicinal chemistry. Here are some notable points regarding its solubility:

  • Polar vs Nonpolar Solvents: TMN tends to be more soluble in polar solvents, such as ethanol and methanol, due to the presence of hydroxyl groups which can engage in hydrogen bonding.
  • Insolubility in Water: Despite its polar nature, TMN displays limited solubility in water, with a tendency to precipitate out due to its substantial hydrophobic naphthalene backbone.
  • Interaction with Other Compounds: In mixed solvent systems, the solubility of TMN can improve significantly, showcasing its capability to form complexes through interactions with various ligands.

In summary, the solubility of 5-hydroxy-7-methyl-naphthalene-1,4-dione can be summarized as follows:

  1. Good solubility in polar organic solvents
  2. Poor solubility in aqueous solutions
  3. Potential for increased solubility in mixed solvents

This intricate balance of solubility is crucial for its reactivity and utility in various chemical reactions, making it an interesting compound for further study.

Interesting facts

Interesting Facts about 5-Hydroxy-7-Methyl-Naphthalene-1,4-Dione

5-Hydroxy-7-methyl-naphthalene-1,4-dione, commonly known as lawsonia, is a fascinating compound primarily derived from the leaves of the henna plant (Lawsonia inermis). This compound has garnered considerable attention due to its distinct properties and applications in various fields. Here are some intriguing aspects of this chemical:

  • Natural Dye: Lawsonia is renowned for its natural dyeing properties. It has been used for centuries in textiles, body art, and hair coloring. The rich colors produced are not only aesthetically pleasing but also have cultural significance in many societies.
  • Biological Activity: This compound exhibits various biological activities, including antioxidant and anti-inflammatory properties. This has prompted research into its potential therapeutic applications, especially in traditional medicine.
  • Cosmetic Use: Due to its ability to bind to keratin, 5-hydroxy-7-methyl-naphthalene-1,4-dione is a popular ingredient in cosmetics and hair products for enhancing color and conditioning effects.
  • Research Interest: Scientists are actively investigating its potential effects on skin and hair health. Ongoing studies aim to explore its mechanisms of action and possible benefits in dermatology.
  • Historical Significance: The use of henna and its derivatives dates back to ancient civilizations, including the Egyptians and Indus Valley cultures, highlighting its historical and cultural importance.

In summary, 5-hydroxy-7-methyl-naphthalene-1,4-dione is not just a chemical compound; it is a bridge between nature and human tradition, embodying a blend of science, art, and culture. As researchers continue to unravel its mysteries, this compound may hold even more secrets waiting to be discovered.

Synonyms
7-Methyljuglone
Ramentaceone
14787-38-3
5-hydroxy-7-methylnaphthalene-1,4-dione
7-Methyljuglon
JUGLONE, 7-METHYL-
5-Hydroxy-7-methyl-1,4-naphthoquinone
5-Hydroxy-7-methyl-1,4-naphthalenedione
1,4-Naphthalenedione, 5-hydroxy-7-methyl-
ZS3RW9P6DY
1,4-NAPHTHOQUINONE, 5-HYDROXY-7-METHYL-
NSC-208733
NSC-624625
4-08-00-02374 (Beilstein Handbook Reference)
5-hydroxy-7-methyl-naphthalene-1,4-dione
DTXSID80163824
DTXCID8086315
7-METHYL-JUGLONE
NSC208733
CHEBI:8773
CHEMBL430853
NSC624625
C11H8O3
NSC 208733
NSC 624625
BRN 2047829
5-Hydroxy-7-methyl-2,3-dihydronaphthal-ene-1,4-dione
7-Methyl juglon
UNII-ZS3RW9P6DY
1, 5-hydroxy-7-methyl-
orb1702883
SCHEMBL5904880
SCHEMBL30594728
BDBM50107009
AKOS006278204
5-Hydroxy-7-methyl-[1,4]naphthoquinone
5-Hydroxy-7-methyll-,1,4-naphtoquinone
NCI60_001745
NCI60_007460
DB-063738
HY-121684
CS-0083051
H27850
Q27108145