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Ipratropium Bromide

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Identification
Molecular formula
C20H30BrNO3
CAS number
22254-24-6
IUPAC name
[5-isopropyl-2-methyl-4-(piperidine-1-carbonyloxy)phenyl]-trimethyl-ammonium;chloride
State
State

At room temperature, ipratropium bromide is typically found as a solid.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.00
Boiling point (Celsius)
286.00
Boiling point (Kelvin)
559.00
General information
Molecular weight
432.38g/mol
Molar mass
432.3770g/mol
Density
1.1750g/cm3
Appearence

Ipratropium bromide is typically a white to off-white crystalline powder. It is odorless and bitter tasting.

Comment on solubility

Solubility of [5-isopropyl-2-methyl-4-(piperidine-1-carbonyloxy)phenyl]-trimethyl-ammonium;chloride

The solubility of this compound, a quaternary ammonium salt, can be quite intriguing due to its unique structure. Here are some key points to consider:

  • Solvent Polarity: Quaternary ammonium salts are often highly soluble in polar solvents, especially water, due to the presence of a positively charged nitrogen atom. This charge allows them to engage in electrostatic interactions with water molecules.
  • Temperature Effects: The solubility typically increases with temperature; heating the solvent can facilitate the dissolution process by providing energy that overcomes any lattice energy present.
  • Influence of Functional Groups: The presence of the piperidine ring and other alkyl groups may enhance or hinder solubility. For instance, bulky groups often reduce solubility in water but may increase solubility in organic solvents.
  • pH Dependence: The solubility can also vary with pH changes, especially if the compound can exist in protonated or deprotonated forms. This can significantly affect its interaction with the solvent.
  • Common Applications: Understanding solubility is crucial for its applications in diverse fields, including pharmaceuticals, where solubility dictates bioavailability.

In summary, despite its complex structure, solubility is primarily influenced by polar interactions, temperature, and functional group presence. This makes predicting solubility a fascinating challenge and an essential part of understanding the behavior of this compound in different environments.

Interesting facts

Interesting Facts about [5-isopropyl-2-methyl-4-(piperidine-1-carbonyloxy)phenyl]-trimethyl-ammonium;chloride

This compound is a fascinating example of a quaternary ammonium salt, which plays a significant role in various biological and chemical processes. Here are some intriguing aspects:

  • Structural Diversity: The compound showcases complex multitasking structures due to the presence of a piperidine ring, which contributes to its unique chemical properties. This ring structure is pivotal in enhancing the compound's efficacy in various applications.
  • Biological Applications: Compounds like this one are often investigated for their potential as pharmaceuticals. The unique functional groups enable interactions with biological macromolecules, making it an interesting candidate for drug development.
  • Ionic Properties: Being a quaternary ammonium compound, it carries a permanent positive charge, enabling it to interact readily with negatively charged functionalities in biomolecules. This characteristic can enhance solubility in polar solvents, which is crucial for biological activity.
  • Versatile Reactivity: The presence of both aromatic and aliphatic components allows this compound to participate in diverse chemical reactions, making it useful in synthetic organic chemistry.
  • Potential Antimicrobial Activity: Many quaternary ammonium compounds exhibit antimicrobial properties, which are of great interest in developing new disinfectants and antiseptics. This compound’s structure may provide avenues for exploring its effectiveness against various pathogens.

As a chemistry student, you may find it helpful to explore its synthesis and modifications, as small changes in the structure can lead to significant variations in biological activity. This compound is a testament to how structure influences functionality, an essential concept in the study of chemical compounds.

Synonyms
AMO 1618
2438-53-1
Amo-1618
N,N,N,2-Tetramethyl-5-(1-methylethyl)-4-((1-piperidinylcarbonyl)oxy)benzenaminium chloride
2-METHYL-4-(PIPERIDIN-1-YLCARBOXY)-5-ISOPROPYLPHENYLTRIMETHYLAMMONIUM CHLORIDE
trimethyl-[2-methyl-4-(piperidine-1-carbonyloxy)-5-propan-2-ylphenyl]azanium;chloride
TL-1049
Ammonium, (5-(piperidinocarbonyloxy)carvacryl)trimethyl-, chloride
1-Piperidinecarboxylic acid, 6-(trimethylammonio)thymyl ester, chloride
Ammonium, (5-hydroxycarvacryl)trimethyl-, chloride, 1-piperidinecarboxylate
Carbamic acid, N,N-pentamethylene-, 4-dimethylaminothymyl ester, methochloride
SPECTRUM1505165
SCHEMBL6342535
CHEMBL1565750
DTXSID90947238
AKOS040750480
NCGC00096055-01
Benzenaminium, N,N,N,2-tetramethyl-5-(1-methylethyl)-4-((1-piperidinylcarbonyl)oxy)-, chloride
(5-hydroxycarvacryl)trimethylammonium chloride 1-piperidinecarboxylate
N,N,N,2-Tetramethyl-4-[(piperidine-1-carbonyl)oxy]-5-(propan-2-yl)anilinium chloride
N,N,N,2-Tetramethyl-5-(methylethyl)-4-[(1-piperidiylcarbonyl)oxy]benzenaminium chloride (1:1)