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Methoxyphenamine

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Identification
Molecular formula
C19H24ClN2O2
CAS number
90717-14-7
IUPAC name
[5-methoxy-1-(4-methoxyphenyl)-2-methyl-indol-3-yl]methyl-dimethyl-ammonium;chloride
State
State

At room temperature, the compound is in a solid state.

Melting point (Celsius)
169.50
Melting point (Kelvin)
442.65
Boiling point (Celsius)
348.20
Boiling point (Kelvin)
621.35
General information
Molecular weight
350.87g/mol
Molar mass
350.8650g/mol
Density
1.1600g/cm3
Appearence

The compound appears as a white crystalline solid.

Comment on solubility

Solubility Characteristics

The compound [5-methoxy-1-(4-methoxyphenyl)-2-methyl-indol-3-yl]methyl-dimethyl-ammonium;chloride is characterized by its unique molecular structure, which can significantly influence its solubility. Understanding the solubility of this compound is important for various applications, especially in medicinal chemistry and material science.

In general, the solubility of such a compound can be influenced by several key factors:

  • Polarity: The presence of the quaternary ammonium group may enhance its solubility in polar solvents such as water. However, the hydrophobic indole and methoxyphenyl groups can counteract this effect.
  • Temperature: Like many ionic compounds, solubility often increases with temperature. Thus, elevated temperatures might improve the dissolution of this compound in aqueous solutions.
  • pH Level: The solubility may also vary with the pH of the solution; under acidic or neutral conditions, the ammonium chloride portion is expected to remain soluble.
  • Ion-Pair Formation: Depending on the presence of ions in the solution, the compound may engage in ion-pair formation, potentially affecting its overall solubility.

“Solubility is a key determinant of bioavailability and reactivity for chemical compounds.” In the case of this compound, conducting empirical solubility tests is essential to draw clear conclusions about its solubility in different solvents and conditions.

Ultimately, precise solubility data would be required to fully understand how [5-methoxy-1-(4-methoxyphenyl)-2-methyl-indol-3-yl]methyl-dimethyl-ammonium;chloride behaves in solution, making experimental investigations critical for practical applications.

Interesting facts

Interesting Facts About [5-Methoxy-1-(4-Methoxyphenyl)-2-Methyl-Indol-3-yl]Methyl-Dimethyl-Ammonium Chloride

This intriguing compound, typically used within the realm of medicinal chemistry, embodies a fusion of structural complexity and pharmacological potential. Here are some fascinating insights into its properties and applications:

  • Pharmacological Relevance: Compounds of this nature often show promise as pharmaceuticals, particularly in the fields of neurochemistry and psychopharmacology, influencing neurotransmitter activity and showing potential in mood modulation.
  • Indole Derivatives: The presence of the indole structure is significant because indoles are known for their role in various biological systems. They are key scaffolds in many biologically active compounds, including serotonin and certain alkaloids.
  • Methoxy Groups: The methoxy groups attached to the phenyl ring are not just functional moieties; they enhance lipophilicity and may influence how the compound interacts with biological membranes, potentially affecting its bioavailability.
  • Dimethyl-Amino Functionality: The dimethylamino group contributes to the overall basicity of the compound, which can play a crucial role in determining the compound's solubility and interaction with receptor sites in living organisms.

Scientists are continually exploring the potential of compounds like these in drug design and development due to their multifaceted roles in biological systems. As stated by researchers, “The synthesis of novel compounds is essential for advancing therapeutic options in the treatment of complex diseases.”

The exploration of such intricate compounds opens doors to new avenues in understanding and treating various health conditions, highlighting the intellectual pursuit of the chemistry community to innovate and discover.

Synonyms
Of-2497
Indole, 3-((dimethylamino)methyl)-5-methoxy-1-(p-methoxyphenyl)-2-methyl-, monohydrochloride
13708-47-9
3-((Dimethylamino)methyl)-5-methoxy-1-(p-methoxyphenyl)-2-methylindole monohydrochloride