5-methoxy-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

Identification

Molecular formula

C₁₅H₂₀N₂O₂S

CAS number

159354-15-1

IUPAC name

5-methoxy-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

State

At room temperature, 5-methoxy-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole is typically found in a solid state. It is stable under standard conditions but should be handled with care in a controlled environment to prevent degradation or reaction with atmospheric moisture.

Melting point (Celsius)

102.00

Melting point (Kelvin)

375.15

Boiling point (Celsius)

312.00

Boiling point (Kelvin)

585.15

General information

Molecular weight

292.41g/mol

Molar mass

292.4090g/mol

Density

1.2600g/cm³

Appearence

The compound is typically a crystalline solid or powder. Its appearance can vary from white to off-white or yellowish, depending on the purity and particle size. It generally maintains a uniform color and consistency.

Comment on solubility

Solubility of 5-methoxy-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

The solubility of 5-methoxy-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole is an interesting topic due to its unique structure and potential applications. Solubility is influenced by various factors, and this compound demonstrates some noteworthy characteristics:

Polar vs. Nonpolar: The presence of the methoxy group and the piperidyl moiety suggest that the compound has both polar and nonpolar characteristics, which can lead to moderate solubility in organic solvents.
Solvent Selection: It is likely to be more soluble in polar aprotic solvents such as DMF or DMSO compared to nonpolar solvents like hexane or toluene.
Temperature Dependency: As with many organic compounds, solubility may increase with temperature, making it easier to dissolve in higher temperatures.
Hydrogen Bonding: The potential for intramolecular or intermolecular hydrogen bonding can complexly influence the solubility, possibly leading to improved solubility in water despite the overall nonpolar characteristics.

In summary, while the solubility of 5-methoxy-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole may present challenges due to its multifaceted structure, understanding its solubility can reveal valuable insights for pharmaceutical formulations and other applications.

Interesting facts

Exploring 5-methoxy-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole

The compound 5-methoxy-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole is a fascinating chemical entity in the field of medicinal chemistry and drug development. Here are some interesting facts about it:

Synthetic Versatility: This compound features a benzoxazole ring, which is a versatile scaffold used in the synthesis of various bioactive molecules. The structural complexity of benzoxazoles often leads to compounds with potential therapeutic properties.
Biological Activity: Compounds containing piperidine rings, like this one, are known for their diverse biological activities, including antipsychotic, analgesic, and anticonvulsant effects. The piperidyl group's incorporation could enhance its pharmacological profile.
Structure-Activity Relationship (SAR): The introduction of a methoxy group and an ethylsulfanyl group may modulate the electronic and steric properties of the compound, impacting its biological activity and receptor interactions.
Potential Applications: Due to its unique structure, it could be explored for applications in treating neurological disorders or as a part of drug discovery pipelines targeting various receptors.
Research Interest: Compounds like this are often the subject of research in both academic and pharmaceutical sectors, as scientists strive to uncover new medicinal uses and improve chemical efficiency.

As with many organic compounds, the journey from molecule synthesis to understanding its potential applications requires a combination of patience, creativity, and rigorous scientific inquiry. As noted in the realm of chemistry - "The beauty of a molecule often lies not only in its structure but in its potential to impact lives."

In conclusion, 5-methoxy-2-[2-(1-piperidyl)ethylsulfanyl]-1,3-benzoxazole stands out as a compelling candidate for further investigation, promising opportunities in the quest for novel therapeutic agents.