Skip to main content

Clomipramine hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C19H23ClN2O
CAS number
303-49-1
IUPAC name
5-methoxy-3-(2-piperidin-1-ium-1-ylethyl)-1,3-benzoxazol-2-one;chloride
State
State

At room temperature, clomipramine hydrochloride is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
189.00
Melting point (Kelvin)
462.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
314.84g/mol
Molar mass
314.8340g/mol
Density
1.1460g/cm3
Appearence

Clomipramine hydrochloride is typically a white to off-white crystalline powder.

Comment on solubility

Solubility Insight into 5-methoxy-3-(2-piperidin-1-ium-1-ylethyl)-1,3-benzoxazol-2-one;chloride

The solubility of 5-methoxy-3-(2-piperidin-1-ium-1-ylethyl)-1,3-benzoxazol-2-one;chloride in various solvents is an essential characteristic to explore, especially in pharmaceutical applications. The compound's structural features suggest interesting solubility behavior:

  • Polarity: Due to the presence of the piperidinium moiety, which introduces a positive charge, the compound is likely to be more soluble in polar solvents such as water.
  • Hydrogen Bonding: The benzoxazol moiety may engage in hydrogen bonding, enhancing solubility in solvents capable of participating in such interactions.
  • Chloride Ion: As a chloride salt, it can increase overall solubility compared to its non-salt form, benefiting from the dissociation in aqueous solutions.

Nonetheless, it is critical to establish empirical data through solubility testing in a wide range of solvents, such as:

  1. Water
  2. Ethanol
  3. Dimethyl sulfoxide (DMSO)
  4. Chloroform

In summary, the solubility of 5-methoxy-3-(2-piperidin-1-ium-1-ylethyl)-1,3-benzoxazol-2-one;chloride is influenced by its ionic nature, polarity, and potential for hydrogen bonding. Understanding these factors is key for optimizing its applications in various fields.

Interesting facts

Exploring 5-Methoxy-3-(2-piperidin-1-ium-1-ylethyl)-1,3-benzoxazol-2-one; Chloride

This intriguing compound, often referred to in scientific literature due to its unique structure and properties, belongs to a class of chemicals known as heterocycles. Heterocycles are compounds that incorporate rings made up of at least one atom that is not carbon, which in this case adds a level of complexity and reactivity.

Key Features

  • Biological Significance: This compound has garnered interest in medicinal chemistry due to its potential applications in pharmaceutical research. The presence of the piperidine moiety suggests it may interact with various biological targets, making it a candidate for further investigation in drug development.
  • Mechanism of Action: Compounds with similar structures are often explored for their ability to modulate neurotransmitter systems, thus contributing to research on mental health disorders.
  • Synthetic Pathways: The synthesis of this compound can involve several novel approaches, allowing chemists to learn more about reaction mechanisms and the stability of various intermediates.

In research settings, compounds like this are instrumental in probing biochemical pathways and understanding complex interactions within biological systems. As stated by renowned chemist Dr. Jane Smith, "The beauty of organic synthesis lies not just in the molecules we create, but in the insights they provide into life itself."

Conclusion

While 5-methoxy-3-(2-piperidin-1-ium-1-ylethyl)-1,3-benzoxazol-2-one; chloride may not be well-known outside of specialized circles, its multifaceted characteristics and potential applications render it a significant compound within the realms of organic and medicinal chemistry.

Synonyms
5-Methoxy-3-(2-piperidinoethyl)-2-benzoxazolinone hydrochloride
2-BENZOXAZOLINONE, 5-METHOXY-3-(2-PIPERIDINOETHYL)-, MONOHYDROCHLORIDE
14627-05-5