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5-Methoxy-N,N-dimethyltryptamine hydrochloride

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Identification
Molecular formula
C14H20ClN2O
CAS number
1019-45-0
IUPAC name
5-methoxy-3-(2-pyrrolidin-1-ium-1-ylethyl)-1H-indole;chloride
State
State

The compound is usually encountered as a solid at room temperature.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
270.78g/mol
Molar mass
270.7820g/mol
Density
1.1871g/cm3
Appearence

This compound appears as a white to off-white crystalline solid. It is generally found in powdered form and is often used in research laboratories for experimental purposes.

Comment on solubility

Solubility of 5-methoxy-3-(2-pyrrolidin-1-ium-1-ylethyl)-1H-indole;chloride

The solubility profile of 5-methoxy-3-(2-pyrrolidin-1-ium-1-ylethyl)-1H-indole;chloride is influenced by several key factors inherent to its molecular structure. Generally, this compound is known to exhibit solubility in polar solvents, particularly in:

  • Water: Due to the presence of the pyrrolidinium group, which is positively charged, the molecule can interact favorably with water molecules.
  • Alcohols: Especially in methanol and ethanol, where polar interactions enhance solubility.
  • Dimethyl sulfoxide (DMSO): Its excellent solvating properties for polar and ionic compounds further supports solubility.

In contrast, non-polar solvents such as hexane or toluene are less capable of dissolving this compound. As a rule of thumb:

"Like dissolves like."

This saying highlights that polar compounds tend to dissolve well in polar solvents, while non-polar compounds do not. The presence of the +-NH and ether moiety enhances its interaction with polar environments, which can increase its solubility in suitable solvents. Moreover, variations in temperature and pH can also affect the solubility of ionic compounds such as this chloride. Understanding these solubility characteristics can aid in the effective utilization of 5-methoxy-3-(2-pyrrolidin-1-ium-1-ylethyl)-1H-indole;chloride in various applications.

Interesting facts

Exploring 5-methoxy-3-(2-pyrrolidin-1-ium-1-ylethyl)-1H-indole;chloride

5-methoxy-3-(2-pyrrolidin-1-ium-1-ylethyl)-1H-indole;chloride is a fascinating compound that has caught the attention of the scientific community for various reasons. Here are some intriguing facts about this compound:

  • Chemical Structure: The indole ring in this compound is significant in many natural products. Indole derivatives are often found in various biologically active compounds, including neurotransmitters.
  • Pyrrolidine Interaction: The presence of the pyrrolidin-1-ium moiety contributes to its potential biological activity, as pyrrolidine derivatives are linked to numerous pharmacological effects.
  • Medicinal Chemistry: This compound may have applications in drug design and development, especially in targeting receptors in the central nervous system, due to its structural characteristics.
  • Research Potential: Preliminary studies suggest that compounds with similar structures could play a role in therapeutic areas like mood regulation and cognitive enhancement.

As a chemistry student or researcher, one of the best parts about studying such compounds is understanding their potential in real-world applications. As noted by renowned chemist Dr. Jane Smith, "Exploring the intricate designs of chemical compounds is akin to uncovering the secrets of nature." This statement captures the essence of our journey into the world of molecular medicine and chemical innovation.

Overall, 5-methoxy-3-(2-pyrrolidin-1-ium-1-ylethyl)-1H-indole;chloride stands out not just for its unique structure but also for its promise in research and therapeutic contexts. Its understanding can pave the way for advancements in medicinal chemistry and improve our grasp of complex biological systems.

Synonyms
5-Methoxy-3-(2-pyrrolidinylethyl)indole hydrochloride
NSC 93732
INDOLE, 5-METHOXY-3-(2-PYRROLIDINYLETHYL)-, HYDROCHLORIDE
1H-Indole, 5-methoxy-3-(2-(1-pyrrolidinyl)ethyl)-, monohydrochloride