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5-Methyl-1,3-benzothiazol-2-amine

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Identification
Molecular formula
C8H8N2S
CAS number
35853-60-8
IUPAC name
5-methyl-1,3-benzothiazol-2-amine
State
State

At room temperature, 5-methyl-1,3-benzothiazol-2-amine is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
338.00
Boiling point (Kelvin)
611.15
General information
Molecular weight
164.24g/mol
Molar mass
164.2440g/mol
Density
1.3000g/cm3
Appearence

5-Methyl-1,3-benzothiazol-2-amine typically appears as a yellow or off-white crystalline powder. This compound can be identified by its crystalline structure which is commonly seen in many solid chemical compounds.

Comment on solubility

Solubility of 5-methyl-1,3-benzothiazol-2-amine

The solubility of 5-methyl-1,3-benzothiazol-2-amine can be described as complex due to its unique chemical structure. This compound is a derivative of benzothiazole, which generally impacts its solubility in various solvents. Key points to consider include:

  • Polar vs. Non-Polar Solvents: The presence of nitrogen and sulfur in the thiazole ring may increase the compound's solubility in polar solvents such as water and methanol, but it may exhibit limited solubility in non-polar solvents.
  • Hydrogen Bonding: Potential for hydrogen bonding due to the amine group, which could enhance solubility in aqueous environments.
  • pH Dependence: The solubility might vary with pH, particularly if the amine group is protonated in acidic conditions, affecting how it interacts with solvents.

In summary, while the solubility of 5-methyl-1,3-benzothiazol-2-amine is influenced by various factors, it is generally more soluble in polar solvents, helping it to dissolve effectively in environments suitable for biochemical applications. This compound exemplifies how chemical structure intricately governs the behavior of solubility across different mediums.

Interesting facts

Interesting Facts about 5-methyl-1,3-benzothiazol-2-amine

The compound known as 5-methyl-1,3-benzothiazol-2-amine is a fascinating member of the benzothiazole family, a class of organic compounds renowned for their diverse applications in various fields ranging from pharmaceuticals to materials science.

Key Attributes:

  • Biological Activity: It has been investigated for its potential role as a pharmaceutical agent, demonstrating various biological activities, including antimicrobial and antifungal properties.
  • Research Applications: This compound serves as an important intermediate in the synthesis of other complex molecules, often acting as a building block in medicinal chemistry.
  • Fluorescent Properties: Certain derivatives of benzothiazoles exhibit intriguing fluorescence, making them useful in applications such as organic light-emitting diodes (OLEDs) and sensors.

Moreover, 5-methyl-1,3-benzothiazol-2-amine can be involved in various chemical reactions, as it is a versatile molecule. For instance, it can participate in both nucleophilic substitutions and electrophilic aromatic substitutions, showcasing its reactivity.

As you delve into the world of this compound, you may find interesting connections to environmental chemistry as well. Certain benzothiazole derivatives are known for their roles in biological systems, and understanding their mechanisms can be crucial for developing better treatments for diseases. According to a research article, "Benzothiazole compounds hold promise as lead compounds for new therapeutic agents," highlighting the ongoing exploration in this field.

This compound not only embodies the complexity of chemistry but also invites inquisitive minds to explore its myriad possibilities in innovation and research.

Synonyms
2-Amino-5-methylbenzothiazole
5-Methyl-2-aminobenzothiazole
5-methyl-1,3-benzothiazol-2-amine
BENZOTHIAZOLE, 2-AMINO-5-METHYL-
5-Methyl-2-benzothiazolamine
4C5GV4TQ4N
NSC 45346
BRN 0122353
NSC-45346
DTXSID40163800
4-27-00-04908 (Beilstein Handbook Reference)
DTXCID7086291
14779-17-0
2-Benzothiazolamine, 5-methyl-
5-methylbenzo[d]thiazol-2-amine
MFCD00205354
UNII-4C5GV4TQ4N
SCHEMBL12262
SCHEMBL29572251
MELAGXOBBSTJPI-UHFFFAOYSA-N
NSC45346
STK281617
AKOS000298702
AS-54796
SY067430
DB-005955
CS-0039099
W10174
A808691