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5-Methylimidazole

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Identification
Molecular formula
C4H6N2
CAS number
822-36-6
IUPAC name
5-methyl-1H-imidazole
State
State

At room temperature, 5-methylimidazole is typically in the form of a solid, specifically as crystalline powder.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
267.80
Boiling point (Kelvin)
541.00
General information
Molecular weight
82.11g/mol
Molar mass
82.1090g/mol
Density
1.0300g/cm3
Appearence

5-Methylimidazole typically appears as a white to pale yellow crystalline powder. It is often characterized by its solid form under standard conditions.

Comment on solubility

Solubility of 5-methyl-1H-imidazole

5-methyl-1H-imidazole is known for its diverse chemical properties, particularly its solubility characteristics. This compound is recognized as being:

  • Soluble in Water: Due to the presence of nitrogen atoms within its imidazole ring, it exhibits a good degree of solubility in polar solvents like water.
  • Highly Soluble in Organic Solvents: 5-methyl-1H-imidazole is also soluble in a variety of organic solvents, such as methanol and ethanol, allowing it to participate readily in organic reactions.
  • Limited Solubility in Non-Polar Solvents: It does not dissolve well in non-polar solvents, which is typical for polar compounds.

These solubility traits make 5-methyl-1H-imidazole a versatile compound, suitable for various applications in chemical synthesis and biological systems. As with many solutes, temperature and pressure can affect its solubility, so experimental conditions can play a significant role in its behavior.

In conclusion, understanding the solubility of 5-methyl-1H-imidazole not only enhances its utility but also contributes to the knowledge of how such compounds behave in different environments.

Interesting facts

Interesting Facts about 5-Methyl-1H-Imidazole

5-Methyl-1H-imidazole is a fascinating organic compound that belongs to the imidazole family, which is known for its presence in various biological systems and functions. Here are some intriguing facets of this compound:

  • Biological Importance: Imidazole derivatives play a crucial role in biochemistry, particularly in the structure of amino acids and neurotransmitters. Their presence in histidine, an essential amino acid, highlights their significance in protein synthesis.
  • Pharmaceutical Applications: Compounds containing the imidazole ring have been incorporated into numerous drugs, particularly those that combat fungal infections. For instance, the antifungal agent clotrimazole is derived from imidazole.
  • Coordination Chemistry: 5-Methyl-1H-imidazole is also known to coordinate with various metal ions, making it valuable in the design of metal-organic frameworks and catalysts.
  • Flavor and Fragrance: This compound can contribute to the flavor profile of certain foods. Indeed, imidazole derivatives are often found in food chemistry and can influence the aroma of some food products.
  • Environmental Considerations: Understanding and studying such compounds can help in developing strategies for biomimicry and sustainability in environmental chemistry.

As a key player in organic chemistry, 5-methyl-1H-imidazole showcases the intricate connections between chemical structure and biological function, making it a compound worth studying for both aspiring chemists and seasoned scientists alike. Its diverse applications underscore the importance of investigating imidazole derivatives in various fields, from pharmaceuticals to food science.

Synonyms
4-Methylimidazole
822-36-6
4-Methyl-1H-imidazole
4(5)-Methylimidazole
1H-Imidazole, 4-methyl-
4-Me-i
5-Methylimidazole
4(or 5)-Methylimidazole
IMIDAZOLE, 4-METHYL-
4-MEI
1H-Imidazole, 5-methyl-
CHEBI:40035
EINECS 212-497-3
Q64GF9FV4I
NSC 40744
CCRIS 8912
DTXSID9025617
AI3-08274
HSDB 7757
S-3-furyl ethanethioate
NSC-40744
DTXCID805617
4-METHYLIMIDAZOLE [HSDB]
4-METHYLIMIDAZOLE [IARC]
EC 212-497-3
ethanethioic acid, S-3-furanyl ester
4-METHYLIMIDAZOLE (IARC)
4Methyl1Himidazole
Imidazole, 4methyl
1HImidazole, 4methyl
1HImidazole, 5methyl
4(or 5)Methylimidazole
Imidazole, 4 (or 5)-methyl-
4-ME-1
212-497-3
5-Methyl-1H-imidazole
MFCD00005201
CHEMBL1230309
928113-28-4
4-methyl imidazole
5-methyl imidazole
4MI
4MZ
UNII-Q64GF9FV4I
4-methylimidazol
4-methyl-imidazole
4-methyl-1-H-imidazole
5-Methyl-1H-imidazole #
imidazole, 4(5)-methyl-
4-methyl-1(3)H-imidazole
WLN: T5M CNJ D1
MLS001065586
4(5)-Methylimidazole, 98%
HMS3039G17
CS-D1459
NSC40744
Tox21_201048
BDBM50538684
MFCD02114698
STL185694
AKOS005206795
AKOS006242099
AC-4534
CCG-214463
DB03385
FM38077
NCGC00091437-01
NCGC00091437-02
NCGC00258601-01
AS-12430
CAS-822-36-6
PD002162
SMR000568466
4(5)-Methylimidazole, analytical standard
M0636
NS00010164
EN300-78401
C19262
AL-398/25017073
Q230021
Z1945707502