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5-methyl-1H-pyrazole

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Identification
Molecular formula
C4H6N2
CAS number
1558-50-7
IUPAC name
5-methyl-1H-pyrazole
State
State

At room temperature, 5-methyl-1H-pyrazole is a liquid. It remains stable under standard conditions but can volatilize due to its relatively low boiling point compared to higher molecular weight compounds.

Melting point (Celsius)
7.00
Melting point (Kelvin)
280.15
Boiling point (Celsius)
204.00
Boiling point (Kelvin)
477.15
General information
Molecular weight
82.11g/mol
Molar mass
82.1090g/mol
Density
0.9836g/cm3
Appearence

5-Methyl-1H-pyrazole is a colorless liquid with a pyridine-like odor. Its appearance is typical of many volatile organic compounds, being clear and transparent. The liquid may form various crystalline structures at different purities and can solidify under certain conditions.

Comment on solubility

Solubility of 5-methyl-1H-pyrazole

5-methyl-1H-pyrazole, a heterocyclic compound, exhibits interesting solubility characteristics that are worth exploring. Its solubility can be influenced by several factors:

  • Polarity: As a polar compound, 5-methyl-1H-pyrazole is generally soluble in polar solvents, such as water and alcohol.
  • Hydrogen Bonding: The compound can form hydrogen bonds, which enhances its solubility in protic solvents.
  • Temperature Dependency: The solubility of 5-methyl-1H-pyrazole may increase with temperature, a common phenomenon for many organic compounds.

In practical applications, "like dissolves like" can be utilized to optimize solubility, meaning that choosing solvents with similar polarities can lead to better dissolution rates. The potential for 5-methyl-1H-pyrazole to interact with other substances is significant, making it a valuable compound in various chemical contexts.


Overall, understanding the solubility of 5-methyl-1H-pyrazole is crucial for its effective application in research and industry, as it dictates its behavior in different environments.

Interesting facts

Interesting Facts about 5-Methyl-1H-Pyrazole

5-methyl-1H-pyrazole is a fascinating compound within the realm of organic chemistry, known for its unique structural properties and diverse applications. Here are some remarkable aspects that highlight its significance:

  • Structural Importance: This compound belongs to the class of pyrazoles, which are five-membered heterocyclic compounds containing two nitrogen atoms. The presence of a methyl group at the fifth position contributes to its distinct reactivity and chemical behavior.
  • Versatile Reactions: 5-methyl-1H-pyrazole acts as a useful building block in the synthesis of various chemical compounds. It can participate in numerous reactions, including nucleophilic substitutions and formation of derivatives, making it a valuable synthetic tool in organic chemistry.
  • Biological Relevance: This compound has garnered interest in medicinal chemistry due to its potential biological activities. Some derivatives of 5-methyl-1H-pyrazole have been studied for their anti-inflammatory and anti-tumor properties, showcasing the importance of pyrazole derivatives in pharmaceutical research.
  • Applications in Agriculture: Compounds like 5-methyl-1H-pyrazole have found application in the formulation of agrochemicals, particularly among herbicides and fungicides. Its ability to interact with biochemical pathways in plants makes it a subject of study in agricultural science.
  • Research Potential: Ongoing research continues to explore the vast possibilities related to this compound. Chemists are interested in developing new members of the pyrazole family or enhancing the properties of existing ones, leading to innovative applications in various fields.

In conclusion, 5-methyl-1H-pyrazole exemplifies the intersection of basic research and practical application, serving as a testament to the dynamic nature of chemical science. As researchers explore its capabilities further, who knows what new discoveries await?

Synonyms
3-Methylpyrazole
1453-58-3
1H-Pyrazole, 3-methyl-
5-Methylpyrazole
3(5)-Methylpyrazole
Pyrazole, 5-methyl-
PYRAZOLE, 3-METHYL-
W7KU1RRO6U
EINECS 215-925-7
BRN 0001454
DTXSID3073260
EC 215-925-7
5-23-05-00004 (Beilstein Handbook Reference)
3Methylpyrazole
5Methylpyrazole
3Methyl1Hpyrazole
Pyrazole, 5methyl
3(5)Methylpyrazole
1HPyrazole, 3methyl
DTXCID0034726
215-925-7
5-methyl-1H-pyrazole
3-Methyl-1H-pyrazole
88054-14-2
1H-Pyrazole,5-methyl-
1H-Pyrazole, 5-methyl-
methylpyrazole
MFCD00005240
MFCD08685900
CHEMBL3275944
UNII-W7KU1RRO6U
3-methyl-pyrazole
3-Methyl pyrazole
Pyrazole, 3(or 5)-methyl- (6CI,7CI); Pyrazole, 3-methyl- (8CI); 3-Methyl-1H-pyrazole; 3-Methylpyrazole; 5-Methylpyrazole
3-methyl-1-H-pyrazole
3-Methyl-1,2-diazole
3-Methylpyrazole, 97%
pyrazole, 3(5)-methyl-
3-methyl-1(2)H-pyrazole
Pyrazole, 3(or 5)-methyl-
5-Methyl-1H-pyrazole, AldrichCPR
ALBB-006081
ASP-3325
BCP23867
CS-B0947
STR06996
BDBM50497139
s5146
STK263690
AKOS000265788
AKOS000311487
AC-2646
CCG-266014
FD18008
FM11798
HY-66054
DB-028555
M0564
NS00001409
EN300-44939
3-Methylpyrazole, analytical reference material
Q27292441
F9995-1460
Z450469310