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5-Methyl-2-nitroimidazole

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Identification
Molecular formula
C4H5N3O2
CAS number
1984-76-1
IUPAC name
5-methyl-2-nitro-1H-imidazole
State
State

At room temperature, 5-methyl-2-nitroimidazole is in a solid state. It is typically stable and does not decompose under normal conditions.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.20
Boiling point (Celsius)
306.50
Boiling point (Kelvin)
579.60
General information
Molecular weight
127.10g/mol
Molar mass
127.1040g/mol
Density
1.4500g/cm3
Appearence

5-Methyl-2-nitroimidazole is a pale yellow crystalline solid. It may appear as a powder or in small crystal forms.

Comment on solubility

Solubility of 5-methyl-2-nitro-1H-imidazole

5-methyl-2-nitro-1H-imidazole, a compound known for its unique structure, exhibits interesting solubility characteristics that may influence its applications and behavior in various environments. Here’s what you need to know:

  • Polar Functional Groups: The presence of both a nitro group and an imidazole ring suggests that this compound is likely to be polar.
  • Solvent Compatibility: It is expected to be soluble in polar solvents like water and ethanol, while showing limited solubility in non-polar solvents due to its polar nature.
  • Temperature Dependence: Like many organic compounds, the solubility of 5-methyl-2-nitro-1H-imidazole may increase with higher temperatures, allowing for greater molecular interactions with solvents.

In practical terms, the solubility of this compound can be critical for its use in pharmaceuticals, agrochemicals, and other chemical processes. It is also important to note that the specific conditions such as pH and ionic strength of the solution might further influence its solubility. Thus, understanding these factors is essential for optimizing its use.

Interesting facts

Interesting Facts about 5-Methyl-2-nitro-1H-imidazole

5-Methyl-2-nitro-1H-imidazole is a fascinating compound that belongs to the class of imidazoles, which are five-membered heterocyclic compounds featuring two nitrogen atoms in the ring. Here are some intriguing aspects of this compound:

  • Biological Importance: Compounds in the imidazole family, including 5-methyl-2-nitro-1H-imidazole, play significant biological roles. They are often found in various natural products and pharmaceuticals, contributing to diverse biological activities.
  • Application in Drug Development: The structure of 5-methyl-2-nitro-1H-imidazole makes it a valuable target in medicinal chemistry. Its derivatives are investigated for their potential as antifungal and antibacterial agents, particularly against resistant strains.
  • Synthetic Versatility: The synthesis of this compound can be achieved through various synthetic strategies, showcasing the versatility of organic reactions. This allows chemists to explore different pathways to obtain the desired structure efficiently.
  • Reactivity Profile: The nitro group present in 5-methyl-2-nitro-1H-imidazole can participate in multiple chemical reactions. This includes reduction to amines, which opens up avenues for creating new compounds with potentially enhanced biological properties.
  • Environmental Considerations: As with many nitro-containing compounds, it is essential to consider the environmental impact of their synthesis and use. Understanding their degradation pathways can inform safety protocols and waste management practices in laboratories.

In summary, 5-methyl-2-nitro-1H-imidazole stands out not only for its structure but also for its potential applications and the important role it plays in pharmaceutical chemistry. As research continues to evolve, we may uncover even more exciting properties and uses for this intriguing compound!

Synonyms
5-methyl-2-nitro-1H-imidazole
5213-35-4
4-Methyl-2-nitroimidazole
METHYLNITROIMIDAZOLE
Imidazole, 4-methyl-2-nitro-
1H-Imidazole, 4-methyl-2-nitro-
4-methyl-2nitroimidazole
5-Methyl-2-nitroimidazole
5-methyl-2-nitro-imidazole
SCHEMBL1979559
DTXSID90200133
4-Methyl-2-nitro-1H-imidazole #
FAA21335
AKOS006346846
Imidazole, 4(or 5)-methyl-2-nitro-