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(5-Methyl-2,3-dihydrobenzofuran-2-yl)methanamine

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Identification
Molecular formula
C10H13NO
CAS number
88611-26-7
IUPAC name
(5-methyl-2,3-dihydrobenzofuran-2-yl)methanamine
State
State
The compound is generally in a liquid state at room temperature due to its relatively low melting point.
Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
130.00
Boiling point (Kelvin)
403.15
General information
Molecular weight
163.22g/mol
Molar mass
163.2230g/mol
Density
1.0200g/cm3
Appearence

The compound is typically a clear, colorless liquid when at room temperature. It may appear slightly yellow if impurities are present.

Comment on solubility

Solubility of (5-methyl-2,3-dihydrobenzofuran-2-yl)methanamine

The solubility of (5-methyl-2,3-dihydrobenzofuran-2-yl)methanamine can be influenced by various factors, including its molecular structure and the presence of functional groups. Understanding its solubility is essential for predicting its behavior in different environments, particularly in biochemical applications.

Factors Affecting Solubility:

  • Hydrophilicity vs. Hydrophobicity: The presence of amino groups (-NH2) enhances hydrophilicity, whereas the aromatic ring contributes to hydrophobic interactions.
  • pH Levels: Solubility can change with pH; for instance, at low pH, the amine group may become protonated, increasing solubility in aqueous environments.
  • Temperature: Like many amines, solubility may increase with rising temperature due to greater molecular motion.

General Solubility Insights:

Due to its complex structure, (5-methyl-2,3-dihydrobenzofuran-2-yl)methanamine is likely to exhibit:

  • Moderate solubility in polar solvents like water due to the possible formation of hydrogen bonds.
  • Higher solubility in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO).

In conclusion, understanding the solubility of (5-methyl-2,3-dihydrobenzofuran-2-yl)methanamine is vital for applications ranging from drug formulation to environmental chemistry. Further experimental evaluation is encouraged to obtain precise solubility data under various conditions.

Interesting facts

Intriguing Insights into (5-methyl-2,3-dihydrobenzofuran-2-yl)methanamine

(5-methyl-2,3-dihydrobenzofuran-2-yl)methanamine is a fascinating compound that has attracted interest in various fields of chemistry. This compound is noteworthy due to its unique structural characteristics and potential applications.

Structural Significance

The molecule contains a dihydrobenzofuran core, an intriguing structure that combines a six-membered aromatic ring with a five-membered ether-containing ring. This dual-ring system contributes to its interesting chemical reactivity and biological activity.

Potential Applications

Some of the potential applications of this compound include:

  • Pharmaceutical Development: It may serve as a scaffold in the synthesis of new drugs, especially in the field of neuropharmacology.
  • Agricultural Chemistry: Its derivatives could possibly be explored as agrochemicals or biopesticides due to their bioactive properties.
  • Material Science: The compound might find uses in developing polymers or other materials with specific functional properties.

Biological Interest

Compounds with a similar framework have been studied for their therapeutic potential. Evidence suggests they can exhibit activities such as:

  • Antidepressant effects
  • Antioxidant properties
  • A neuroprotective role in neurodegenerative diseases

Research Directions

Ongoing research aims to explore the synthesis of various derivatives of (5-methyl-2,3-dihydrobenzofuran-2-yl)methanamine, which could lead to the discovery of more potent analogs. Scientists are particularly interested in understanding structure-activity relationships (SAR) to optimize the desirable biological effects while minimizing side effects.

This compound exemplifies the intricate designs found in organic chemistry, highlighting how small changes in molecular structure can lead to significant differences in biological activities and applications. Its exploration could unveil new opportunities within medicinal chemistry and beyond.

Synonyms
SCHEMBL13059461
AKOS013465405