5-Methyl-3-(1-piperidylmethyl)isoxazole

Identification

Molecular formula

C₁₀H₁₆N₂O

CAS number

99740-54-4

IUPAC name

5-methyl-3-(1-piperidylmethyl)isoxazole

State

At room temperature, 5-Methyl-3-(1-piperidylmethyl)isoxazole is in a liquid state. It is imperative to handle it under standard laboratory conditions to maintain its integrity and prevent unwanted reactions or evaporation.

Melting point (Celsius)

-30.00

Melting point (Kelvin)

243.15

Boiling point (Celsius)

282.00

Boiling point (Kelvin)

555.15

General information

Molecular weight

180.24g/mol

Molar mass

180.2410g/mol

Density

1.1140g/cm³

Appearence

5-Methyl-3-(1-piperidylmethyl)isoxazole is typically a colorless to pale yellow liquid. It may appear slightly viscous depending on the temperature and its purity. This compound, as with many organic liquids, may develop a thin oily film on smooth surfaces when spilled.

Comment on solubility

Solubility of 5-methyl-3-(1-piperidylmethyl)isoxazole

The solubility of 5-methyl-3-(1-piperidylmethyl)isoxazole in various solvents is an important aspect to consider for its applications and uses. This compound exhibits a range of solubility characteristics influenced by its chemical structure.

Key Points on Solubility:

Polar Solvents: 5-methyl-3-(1-piperidylmethyl)isoxazole tends to be more soluble in polar solvents such as water and methanol due to its potential hydrogen-bonding capability.
Non-Polar Solvents: The compound may have lower solubility in non-polar solvents like hexane or toluene, as its structural features do not favor interactions with these types of solvents.
pH-Dependent Solubility: The solubility can vary with pH, as the presence of protonated amine groups from the piperidine ring may enhance solubility in acidic conditions.
Temperature Effects: Increasing temperature generally increases solubility for many organic compounds, and this is likely true for 5-methyl-3-(1-piperidylmethyl)isoxazole as well.

As a result, it is advisable to consider the solvent choice based on the intended application, keeping in mind that the solubility behavior can be optimized through conditions such as temperature and pH. Understanding these solubility characteristics is crucial for the successful formulation and utilization of this compound in various scientific and industrial applications.

Interesting facts

Interesting Facts about 5-methyl-3-(1-piperidylmethyl)isoxazole

5-methyl-3-(1-piperidylmethyl)isoxazole is a fascinating compound belonging to the isoxazole family, which is renowned for its unique five-membered ring structure containing both nitrogen and oxygen. Scientists have been intrigued by this compound for various reasons:

Pharmaceutical Applications: This compound has garnered attention in medicinal chemistry, particularly due to its potential therapeutic properties. Isoxazoles are frequently explored for their neuroactive capabilities, making them candidates for developing treatments for neurological disorders.
Structural Diversity: The structural framework of 5-methyl-3-(1-piperidylmethyl)isoxazole allows for significant functional group variability. The incorporation of a piperidine ring contributes to its chemical reactivity and ability to interact with biological targets, opening avenues for drug design.
Synthesis Methodologies: The synthesis of isoxazoles, including this compound, often involves innovative reactions that leverage the reactivity of nitrile and acyl derivatives. Mastery of these synthetic pathways is crucial for chemists looking to explore and optimize their pharmacological properties.
Research Implications: Ongoing research into isoxazole derivatives has revealed their involvement in various biological activities ranging from anti-inflammatory effects to potential anti-cancer properties, making derivatives of 5-methyl-3-(1-piperidylmethyl)isoxazole important to watch in future clinical studies.

In the words of a famous chemist, "Feeling humble in front of nature is the first step to becoming a great chemist." The exploration of compounds like 5-methyl-3-(1-piperidylmethyl)isoxazole exemplifies this sentiment, as each discovery opens the door to further knowledge and innovation in synthetic and medicinal chemistry. Understanding such compounds not only enhances our comprehension of chemical interactions but also bridges the gap between chemistry and the development of life-changing therapies.

Synonyms

SCHEMBL18932537