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Varenicline chloride

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Identification
Molecular formula
C13H14ClN3O
CAS number
375815-87-5
IUPAC name
5-methyl-3-(2-piperidin-1-ium-1-ylethyl)isoxazole;chloride
State
State

At room temperature, varenicline chloride is in solid form.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
288.00
Boiling point (Kelvin)
561.15
General information
Molecular weight
292.83g/mol
Molar mass
292.8250g/mol
Density
1.1000g/cm3
Appearence

Varenicline chloride typically presents as a white to off-white crystalline powder.

Comment on solubility

Solubility of 5-methyl-3-(2-piperidin-1-ium-1-ylethyl)isoxazole; chloride

The solubility of 5-methyl-3-(2-piperidin-1-ium-1-ylethyl)isoxazole; chloride is influenced by several factors, primarily due to its ionic nature and molecular structure. As a quaternary ammonium salt, it typically exhibits good solubility in polar solvents.

Key Points on Solubility:

  • Water Solubility: Quaternary ammonium compounds like this one tend to dissolve well in water, primarily because of their ionic interactions with water molecules.
  • Solvent Compatibility: In addition to water, polar solvents such as methanol and ethanol may also solubilize this compound effectively.
  • Temperature Effects: Generally, solubility can increase with temperature, enhancing the dissolution of the chloride salt.

However, predicting solubility can sometimes be challenging due to the presence of various substituents which may affect solubility through steric or electronic factors. Ultimately, the solubility profile can be summarized as favorable in polar environments while being less soluble in non-polar solvents. It is essential to conduct empirical solubility tests to optimize its use in practical applications.

Interesting facts

5-methyl-3-(2-piperidin-1-ium-1-ylethyl)isoxazole;chloride

The compound 5-methyl-3-(2-piperidin-1-ium-1-ylethyl)isoxazole;chloride presents an intriguing combination of structural elements that makes it noteworthy in the realm of chemical research. Here are some interesting facts about this compound:

  • Unique Structural Features: The presence of an isoxazole ring, a five-membered aromatic heterocyclic structure, is combined with a piperidine, which is a six-membered saturated ring containing one nitrogen atom. This unique fusion may contribute to diverse biological activities.
  • Biological Significance: Compounds containing isoxazole moieties have been reported to exhibit a variety of pharmacological properties, including anti-inflammatory, analgesic, and antimicrobial activities. This suggests that 5-methyl-3-(2-piperidin-1-ium-1-ylethyl)isoxazole;chloride might hold potential for future medicinal applications.
  • Quaternization: The presence of the piperidin-1-ium moiety indicates that this compound is a quaternary ammonium salt. Such compounds are known for their detergent-like properties and potential use in drug delivery systems, making them significant in pharmaceutical formulations.
  • Research Applications: As researchers explore its properties, 5-methyl-3-(2-piperidin-1-ium-1-ylethyl)isoxazole;chloride could lead to new discoveries in the fields of neurochemistry and medicinal chemistry, particularly in the design of novel therapeutic agents.

Overall, the intriguing structure and potential biological activities of this compound make it a captivating subject for scientists and chemistry students alike, emphasizing the importance of exploring complex compounds and their implications in research.

Synonyms
3-(2-Piperidinoethyl)-5-methylisoxazole hydrochloride
946-96-3
ISOXAZOLE, 5-METHYL-3-(2-PIPERIDINOETHYL)-, HYDROCHLORIDE