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5-Methyl-3-(3-pyridyl)-1,2,4-oxadiazole

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Identification
Molecular formula
C8H7N3O
CAS number
5601-89-0
IUPAC name
5-methyl-3-(3-pyridyl)-1,2,4-oxadiazole
State
State

At room temperature, 5-Methyl-3-(3-pyridyl)-1,2,4-oxadiazole is in a solid state.

Melting point (Celsius)
65.00
Melting point (Kelvin)
338.15
Boiling point (Celsius)
316.00
Boiling point (Kelvin)
589.15
General information
Molecular weight
161.16g/mol
Molar mass
161.1570g/mol
Density
1.1800g/cm3
Appearence

5-Methyl-3-(3-pyridyl)-1,2,4-oxadiazole typically appears as a white or off-white crystalline powder. The compound is characterized by fine crystals that may exhibit a slight yellowish tint when impurities are present.

Comment on solubility

Solubility of 5-methyl-3-(3-pyridyl)-1,2,4-oxadiazole

The solubility of 5-methyl-3-(3-pyridyl)-1,2,4-oxadiazole (C8H7N3O) is an intriguing subject, primarily due to its structural components which influence its interaction with solvents. This compound is a derivative of oxadiazole, a class of compounds known for their diverse applications in various fields.


Typically, the solubility of such compounds can be influenced by the following factors:

  • Polarity: The presence of nitrogen atoms in the heterocyclic structure contributes to its overall polarity, which may enhance its solubility in polar solvents.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the nitrogen and oxygen atoms can facilitate the dissolution process in appropriate solvents.
  • Alkyl Substitution: The methyl group adds some degree of hydrophobic character which can influence solubility in non-polar solvents.

In general, while specific solubility data for 5-methyl-3-(3-pyridyl)-1,2,4-oxadiazole may not be extensively documented, we can infer that:

  • It is likely to exhibit moderate solubility in polar organic solvents such as methanol and ethanol.
  • Its solubility in water may be limited due to the hydrophobic nature introduced by the methyl group.

Understanding the solubility behavior of this compound is crucial for its applications in fields like pharmaceuticals and materials science, where solvent choice can greatly affect functional properties.

Interesting facts

Interesting Facts about 5-methyl-3-(3-pyridyl)-1,2,4-oxadiazole

5-methyl-3-(3-pyridyl)-1,2,4-oxadiazole is quite a fascinating compound with unique properties and applications that make it a point of interest in the field of chemistry. Here are some key points:

  • Structural Diversity: This compound contains a heterocyclic structure, which is significant in medicinal chemistry as it can influence biological activity.
  • Pharmacological Relevance: Oxadiazole derivatives have been studied for their potential as antimicrobial agents, which means they can fight against bacteria and fungi.
  • Metal Complexation: The nitrogen atoms present in the structure allow for formation of stable complexes with transition metals, making it a focus for coordination chemistry research.
  • Versatile Synthetic Methodologies: Various synthetic methods can be employed to prepare this compound, providing a convenient platform for studying and modifying its derivatives for desired properties.
  • Spectral Analysis: The compound can be analyzed using different techniques such as NMR and IR spectroscopy, which reveal structural information critical for understanding its reactivity and interaction with biological systems.

As a student or scientist diving into the world of organic chemistry, exploring compounds like 5-methyl-3-(3-pyridyl)-1,2,4-oxadiazole offers an exciting opportunity to bridge the gap between fundamental chemical principles and real-world applications in drug development and materials science.

Synonyms
10350-69-3
5-Methyl-3-(3-pyridyl)-1,2,4-oxadiazole
3-(5-Methyl-1,2,4-oxadiazol-3-yl)pyridine
5-Methyl-3-(pyridin-3-yl)-1,2,4-oxadiazole
5-methyl-3-pyridin-3-yl-1,2,4-oxadiazole
1,2,4-OXADIAZOLE, 5-METHYL-3-(3-PYRIDYL)-
BRN 0137920
MFCD00264571
4-27-00-09313 (Beilstein Handbook Reference)
SCHEMBL2657248
DTXSID80145882
AKOS027440016