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5-Methyl-3-(5-nitro-2-furyl)isoxazole

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Identification
Molecular formula
C8H6N2O4
CAS number
17092-85-0
IUPAC name
5-methyl-3-(5-nitro-2-furyl)isoxazole
State
State
At room temperature, 5-Methyl-3-(5-nitro-2-furyl)isoxazole is in a solid state. It maintains its structural integrity in standard conditions and is not prone to rapid evaporation or sublimation under normal atmospheric pressure.
Melting point (Celsius)
144.60
Melting point (Kelvin)
417.75
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
204.14g/mol
Molar mass
204.1630g/mol
Density
1.3715g/cm3
Appearence

5-Methyl-3-(5-nitro-2-furyl)isoxazole is typically an off-white to yellow crystalline powder. The color intensity may vary slightly depending on the level of purity and the manufacturing process. It is generally fine and granular in texture.

Comment on solubility

Solubility of 5-methyl-3-(5-nitro-2-furyl)isoxazole

The solubility characteristics of 5-methyl-3-(5-nitro-2-furyl)isoxazole (C10H8N2O3) can be quite intriguing, particularly due to the nature of its chemical structure. Here are some key points to consider regarding its solubility:

  • Polarity: The compound contains both polar and nonpolar functional groups which can influence its solubility in different solvents.
  • Solvent Interaction: Solubility may be enhanced in organic solvents like dimethyl sulfoxide (DMSO) and ethanol, where the compound can form hydrogen bonds and engage in dipole-dipole interactions.
  • Aqueous Solubility: Due to its isoxazole ring and nitro group, aqueous solubility may be limited, primarily resulting in low solubility in water at ambient temperature.
  • Temperature Effects: The solubility profile can change significantly with temperature; often, increased temperature can enhance solubility in organic solvents.

In conclusion, while 5-methyl-3-(5-nitro-2-furyl)isoxazole shows potential solubility in certain organic solvents, its behavior in water emphasizes the role of molecular structure in determining solubility. Therefore, understanding these solubility dynamics is crucial for applications and further studies.

Interesting facts

Interesting Facts About 5-methyl-3-(5-nitro-2-furyl)isoxazole

5-methyl-3-(5-nitro-2-furyl)isoxazole is a fascinating compound that showcases the rich diversity found within organic chemistry. Below are some intriguing aspects of this compound:

  • Structural Significance: This compound features a unique isoxazole ring, which is a five-membered aromatic heterocycle containing both nitrogen and oxygen. The incorporation of a furan ring further enhances its complexity and potential reactivity.
  • Biological Activity: Compounds like 5-methyl-3-(5-nitro-2-furyl)isoxazole have drawn attention due to their potential biological activities. For instance, isoxazole derivatives often exhibit anti-inflammatory and antimicrobial properties, making them important in drug discovery.
  • Applications: The presence of a nitro group in the structure suggests potential applications in material science and medicinal chemistry, particularly in the development of novel pharmaceuticals. The unique properties may open doors to research in areas like agrochemicals or dyes.
  • Research Interest: Scientists continue to explore the reactivity of this class of compounds. The ability to modify the isoxazole structure may lead to a variety of useful derivatives with enhanced functionality.
  • Synthetic Challenges: The synthesis of such compounds can be quite challenging and often requires sophisticated techniques. Understanding these synthesis pathways is crucial for researchers aiming to produce these compounds efficiently.

In summary, 5-methyl-3-(5-nitro-2-furyl)isoxazole not only highlights the intricate beauty of chemical structures but also emphasizes the importance of interdisciplinary research in the fields of chemistry and biology. Its potential applications could pave the way for new discoveries, making it a compound worth studying further.

Synonyms
ISOXAZOLE, 5-METHYL-3-(5-NITRO-2-FURYL)-
7194-19-6
BRN 1114287
5-Methyl-3-(5-nitro-2-furyl)isoxazole
DTXSID40222229