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Nitrofurazone

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Identification
Molecular formula
C7H6N4O4
CAS number
59-87-0
IUPAC name
5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide
State
State

At room temperature, it is a solid.

Melting point (Celsius)
243.00
Melting point (Kelvin)
516.00
Boiling point (Celsius)
447.00
Boiling point (Kelvin)
720.00
General information
Molecular weight
198.15g/mol
Molar mass
198.1450g/mol
Density
1.7170g/cm3
Appearence

Yellow crystalline powder with a faint characteristic odor.

Comment on solubility

Solubility of 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide

When discussing the solubility of 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide, it is essential to consider several factors that contribute to its behavior in various solvents. This compound is a member of the isoxazole family and presents intriguing solubility characteristics.

Key Points on Solubility:

  • Polarity: The presence of multiple functional groups, especially the carboxamide, influences the overall polarity of the molecule, making it more soluble in polar solvents such as water.
  • Solvent Compatibility: It may exhibit varying solubility in organic solvents; often, compounds with nitro and furan groups show better solubility in non-polar or less polar solvents.
  • Temperature Dependence: Like many organic compounds, the solubility can increase with temperature. As temperature rises, solute-solvent interactions may become more favorable, enhancing solubility.
  • Hydrogen Bonding: The capacity to form hydrogen bonds with water molecules can significantly enhance solubility, which is beneficial for bioavailability in pharmacological contexts.

In conclusion, when evaluating the solubility of 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide, it is crucial to recognize the interplay of its molecular structure and the solvent environment. As with many complex organic compounds, careful consideration of these factors can lead to a better understanding of its behavior in different scenarios.

Interesting facts

Interesting Facts about 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide

The compound 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide is a notable example of a versatile organic molecule that has captured the attention of chemists and medicinal researchers alike. Here are some fascinating insights into this compound:

  • Unique Structure: This compound features an isoxazole ring, which is a five-membered heterocyclic compound that includes both nitrogen and oxygen. This unique ring structure is important for its biological activity.
  • Pharmaceutical Potential: Research has revealed that compounds containing isoxazole moieties can exhibit a range of biological activities, including anti-inflammatory and anticancer properties. The presence of the nitro group enhances its reactivity and may contribute to its pharmacological effects.
  • Versatile Applications: Given its interesting structural features, this compound may serve as a lead compound in drug discovery. The ability to modify the substituents on the isoxazole could lead to the development of new pharmaceutical agents.
  • Interdisciplinary Interest: This compound bridges multiple fields of study, including organic chemistry, pharmacology, and medicinal chemistry, illustrating the interdisciplinary nature of modern chemical research.

"The synthesis and modification of isoxazole derivatives could pave the way for developing new therapies."

Overall, 5-methyl-3-(5-nitro-2-furyl)isoxazole-4-carboxamide exemplifies the exciting possibilities inherent in organic compounds. Its structural complexity and potential applications in medicinal chemistry make it a focal point for ongoing research and development.

Synonyms
4-ISOXAZOLECARBOXAMIDE, 5-METHYL-3-(5-NITRO-2-FURYL)-
21787-26-8
5-Methyl-3-(5-nitro-2-furyl)-4-isoxazolecarboxamide
DTXSID80176191