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5-Methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole chloride

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Identification
Molecular formula
C10H16ClN2O
CAS number
1095557-19-1
IUPAC name
5-methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride
State
State

At room temperature, 5-Methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole chloride is in a solid state. It exists as a crystalline substrate and can be handled as a solid compound in manipulations, preparations, and reactions. Due to its solid state, it is relatively stable under standard conditions and is typically used in laboratories and industrial processes in this form.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
230.71g/mol
Molar mass
230.7500g/mol
Density
1.1900g/cm3
Appearence

5-Methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole chloride typically appears as a white crystalline solid. The crystals are often fine and needle-like, making them distinguishable under a microscope. This compound is hygroscopic and should be stored in a well-sealed container to avoid moisture absorption from the air. Its color and finely granulated structure make it easily recognizable in a laboratory setting.

Comment on solubility

Solubility of 5-methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride

When discussing the solubility of 5-methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride, it is essential to consider various factors that influence its solubility in different solvents. This compound, characterized by the presence of a quaternary ammonium group (piperidin-1-ium), often shows notable differences in solubility compared to neutral isoxazole derivatives.

Key Factors Influencing Solubility:

  • Polarity: Due to its charged ammonium group, this compound is likely to exhibit higher solubility in polar solvents such as water or methanol.
  • Hydrogen Bonding: The ability to form hydrogen bonds can enhance solubility in polar solvents, particularly if water is the solvent.
  • Temperature: Elevated temperatures may increase solubility, allowing the compound to dissolve more readily in solvents.

It’s worth noting that, as a chloride salt, 5-methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride is typically more soluble in aqueous solutions compared to its free base form. This supports the notion that ionic compounds often favor solubility in polar environments.

Conclusion:

In summary, the solubility characteristics of 5-methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride underline the interplay between its molecular structure and the nature of the solvent used. Therefore, one should consider both the electronegative traits and the solution environment to adequately predict its dissolution behavior.

Interesting facts

Interesting Facts about 5-methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride

5-methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride is a fascinating compound that showcases the intricate interplay of organic chemistry and medicinal applications. Here are some compelling points about this unique compound:

  • Structural Diversity: This compound features an isoxazole ring, which is known for its five-membered heterocyclic structure. The addition of a piperidin-1-ium group highlights the *structural variety* that can be achieved in synthetic organic chemistry.
  • Potential Therapeutic Applications: Compounds like 5-methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride are often explored for their potential in drug development, particularly in targeting neurological disorders.
  • Isomerism: The presence of methyl and piperidine substitutions introduces possibilities for stereoisomerism, which can significantly impact the biological activity of the compound.
  • Ionizable Nature: The chloride component in this compound indicates its ionic characteristics, a property that can play a significant role in solubility and bioavailability, essential factors in pharmacology.
  • Research Interest: Chemical compounds such as this one are often analyzed for their *neuroactive* properties, making them a subject of interest in pharmacological research.
  • Exciting Synthesis: The synthesis of isoxazole derivatives often involves *various intriguing reactions*, including cycloadditions and rearrangements, making them a delightful challenge for organic chemists.

In summary, 5-methyl-3-(piperidin-1-ium-1-ylmethyl)isoxazole;chloride is not just a mere chemical formula; it represents a nexus of chemical innovation, potential therapeutic usage, and the quests of researchers striving to unlock new medicinal pathways.

Synonyms
3-(Piperidinomethyl)-5-methylisoxazole hydrochloride
943-62-4
ISOXAZOLE, 5-METHYL-3-(PIPERIDINOMETHYL)-, HYDROCHLORIDE