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5-Methyl-4-nitroimidazole

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Identification
Molecular formula
C4H5N3O2
CAS number
3034-38-6
IUPAC name
5-methyl-4-nitro-1H-imidazole
State
State

At room temperature, 5-Methyl-4-nitroimidazole is in a solid state, usually in the form of a yellow crystalline substance. It remains stable and maintains its crystalline form under normal conditions.

Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
336.00
Boiling point (Kelvin)
609.15
General information
Molecular weight
128.10g/mol
Molar mass
128.1020g/mol
Density
1.5100g/cm3
Appearence

5-Methyl-4-nitroimidazole appears as a yellow crystalline solid. It typically forms needle-like crystals and can have a slightly camphor-like odor. Due to its crystalline nature, it may appear somewhat translucent under certain lighting.

Comment on solubility

Solubility of 5-methyl-4-nitro-1H-imidazole

5-methyl-4-nitro-1H-imidazole, a compound characterized by its unique structure, exhibits notable solubility properties. In general, the solubility of this compound can be influenced by several factors:

  • Polarity: Due to the presence of the nitro group, 5-methyl-4-nitro-1H-imidazole is relatively polar. This polarity enhances its solubility in polar solvents such as water and alcohol.
  • Temperature: As with many organic compounds, increasing the temperature typically increases solubility. Warm solvents can often dissolve more of the compound compared to cooler solvents.
  • pH Level: The solubility can also be affected by the pH of the solution, given that imidazole structures can have ionizable protons under certain conditions.
  • Concentration: In highly concentrated solutions, solubility may be limited due to potential aggregation or crystallization of the compound.

It is often noted that “like dissolves like,” and hence, 5-methyl-4-nitro-1H-imidazole’s solubility is best observed in environments that reflect its structural characteristics.

In conclusion, while specific solubility values can vary, awareness of these key factors provides valuable insight into the solubility behavior of 5-methyl-4-nitro-1H-imidazole, making it an interesting subject for further exploration in chemical contexts.

Interesting facts

Interesting Facts About 5-methyl-4-nitro-1H-imidazole

The compound 5-methyl-4-nitro-1H-imidazole is a fascinating member of the imidazole family, well-known for its role in many biochemical processes. Here are some intriguing aspects of this compound:

  • Biological Relevance: Imidazoles, including this compound, play a crucial role in various biological systems. They are often found in several important biomolecules, including histidine and certain alkaloids.
  • Synthesis: The synthesis of 5-methyl-4-nitro-1H-imidazole typically involves the nitration of imidazole derivatives, an essential step in developing pharmaceuticals.
  • Pharmaceutical Applications: Compounds like 5-methyl-4-nitro-1H-imidazole are explored in drug development, particularly as antifungal agents, due to their ability to disrupt fungal cell membranes.
  • Analytical Use: This compound can also serve as a useful analytical standard in laboratories, aiding in the detection and quantification of imidazole derivatives in various samples.
  • Research Potential: Ongoing research explores its potential applications in treating diseases, making it a subject of interest in medicinal chemistry.

In summary, 5-methyl-4-nitro-1H-imidazole is more than just a simple compound; its diverse applications and biological significance highlight the importance of imidazole derivatives in modern science.