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THIQ

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Identification
Molecular formula
C18H23N3
CAS number
86413-14-9
IUPAC name
5-methyl-7,9,10,14b-tetrahydro-6H-isoquinolino[2,1-d][1,4]benzodiazepine
State
State

At room temperature, 5-methyl-7,9,10,14b-tetrahydro-6H-isoquinolino[2,1-d][1,4]benzodiazepine is in a solid state. It remains stable under normal conditions and does not vaporize readily without application of heat or other disturbances.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
369.00
Boiling point (Kelvin)
642.15
General information
Molecular weight
273.35g/mol
Molar mass
273.3530g/mol
Density
1.1900g/cm3
Appearence

5-Methyl-7,9,10,14b-tetrahydro-6H-isoquinolino[2,1-d][1,4]benzodiazepine appears as a white to off-white crystalline solid. It may also appear as a powder depending on its specific formulation or synthesis method employed. The solid is fine and may exhibit a slight sheen under light.

Comment on solubility

Solubility of 5-methyl-7,9,10,14b-tetrahydro-6H-isoquinolino[2,1-d][1,4]benzodiazepine

The solubility of 5-methyl-7,9,10,14b-tetrahydro-6H-isoquinolino[2,1-d][1,4]benzodiazepine is an important aspect that influences its biological activity and pharmacokinetic properties. Generally, its solubility can be affected by several factors:

  • Polarity: This compound contains various functional groups that can affect its interaction with solvents. The presence of nitrogen atoms and rings may enhance its ability to dissolve in polar solvents.
  • Hydrogen Bonding: The capability to form hydrogen bonds can significantly improve solubility in aqueous solutions.
  • Temperature: Increasing the temperature usually increases solubility for many organic compounds.

It is often observed that:

  1. Compounds with similar structures can exhibit varied solubility profiles.
  2. To determine the solubility in specific solvents, empirical measurements are necessary.
  3. pH sensitivity: The compound's solubility may also change with varying pH levels, suggesting that it could be more soluble in acidic or basic environments depending on its ionization state.

In conclusion, understanding the solubility of this complex compound can lead to better application in medicinal chemistry and formulation science, and experimentation is often the key to unlocking its full potential.

Interesting facts

Interesting Facts About 5-Methyl-7,9,10,14b-tetrahydro-6H-isoquinolino[2,1-d][1,4]benzodiazepine

5-Methyl-7,9,10,14b-tetrahydro-6H-isoquinolino[2,1-d][1,4]benzodiazepine is a fascinating compound that belongs to the benzodiazepine family, known for their psychoactive properties. Here are some notable aspects of this intriguing molecule:

  • Structural Complexity: This compound has a unique polycyclic structure, resulting from the fusion of isoquinoline and benzodiazepine frameworks. Such intricate arrangements contribute to its biological activity and specificity.
  • Potential Biological Activity: Compounds within the benzodiazepine class are often explored for their potential in treating conditions such as anxiety, insomnia, and seizures. The structural modifications in this compound may affect its activity and interactions with biological targets, making it a subject of interest for pharmacological studies.
  • Research Opportunities: Investigating the synthesis and application of this compound opens avenues for research into the development of novel therapeutic agents. Its unique structure could lead to new insights into benzodiazepine pharmacodynamics.
  • Historical Context: Benzodiazepines have a rich history, having been widely studied since their introduction in the mid-20th century. This compound reflects the ongoing effort to design derivatives with improved efficacy and reduced side effects.

As a scientist or chemistry student delving into the properties of such compounds, it is crucial to consider both their chemical structure and biological implications. Remember, the exploration of compounds like 5-methyl-7,9,10,14b-tetrahydro-6H-isoquinolino[2,1-d][1,4]benzodiazepine is not just about the chemistry but also about the impact on healthcare and therapeutic developments!

Synonyms
19007-31-9
BRN 0667902
5-Methyl-6,7,9,10-tetrahydro-5H-isoquino(2,1-d)(1,4)benzodiazepine
ISOQUINO(2,1-d)(1,4)BENZODIAZEPINE, 5,6,7,9,10,14b-HEXAHYDRO-5-METHYL-
5,6,7,9,10,14b-Hexahydro-5-methylisoquino[2,1-d][1,4]benzodiazepine
5-methyl-7,9,10,14b-tetrahydro-6H-isoquinolino[2,1-d][1,4]benzodiazepine
DTXSID10940544
5-Methyl-5,6,7,9,10,14b-hexahydroisoquinolino[2,1-d][1,4]benzodiazepine