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5-Methylbenzofuran

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Identification
Molecular formula
C9H8O
CAS number
4265-25-2
IUPAC name
5-methylbenzofuran
State
State
Under standard conditions of temperature and pressure, 5-Methylbenzofuran is a liquid. It is stable at room temperature and primarily used in organic synthesis and research applications.
Melting point (Celsius)
-36.00
Melting point (Kelvin)
237.15
Boiling point (Celsius)
194.00
Boiling point (Kelvin)
467.15
General information
Molecular weight
132.16g/mol
Molar mass
132.1640g/mol
Density
1.0796g/cm3
Appearence
5-Methylbenzofuran is a colorless to pale yellow liquid with a distinctive odor. Its appearance can slightly vary depending on the purity and specific batch, but it typically remains a clear liquid with no visible impurities.
Comment on solubility

Solubility of 5-Methylbenzofuran

5-Methylbenzofuran is a compound that exhibits moderate solubility characteristics which are essential to its applications and behavior in different environments. Understanding its solubility can provide valuable insights into its usage in chemical formulations and organic reactions. Here are some key points to consider:

  • Polar Versus Non-Polar: 5-Methylbenzofuran, being an aromatic compound with a fused ring structure, tends to demonstrate greater solubility in non-polar solvents. This indicates that it dissolves more readily in substances such as hexane or toluene than in water.
  • Hydrophobic Nature: The presence of the methyl group on the benzofuran structure enhances its hydrophobic properties, contributing to its limited solubility in polar solvents like water.
  • Temperature Dependence: Like many organic compounds, the solubility of 5-methylbenzofuran can be influenced by temperature; typically, increased temperature can lead to increased solubility in non-polar solvents.

In conclusion, while 5-methylbenzofuran is not highly soluble in water, it can be effectively utilized in various organic solvents, making it a versatile compound in chemical synthesis and other applications. Remember, when handling it, always consider the solvent environment as it plays a crucial role in the compound's behavior.

Interesting facts

Interesting Facts About 5-Methylbenzofuran

5-Methylbenzofuran is a fascinating compound that bridges the worlds of aromatic chemistry and biological applications. It is part of the benzofuran family, which is known for its distinct fused ring structure that combines a benzene ring with a furan ring. Here are some captivating aspects of this compound:

  • Structural Diversity: The presence of a methyl group in the 5-position of the benzofuran contributes to its structural diversity, making it a valuable scaffold for the synthesis of various derivatives.
  • Biological Relevance: Compounds related to benzofuran have been studied for their potential pharmacological properties, including anti-inflammatory and anticancer activities. This interest highlights the medicinal potential of 5-methylbenzofuran and its derivatives.
  • Natural Occurrence: Benzofurans are often found in nature. Some of them have been isolated from natural sources, which could indicate that 5-methylbenzofuran may also be present in certain plants or fungi, contributing to their chemical profiles.
  • Synthetic Applications: Chemists utilize 5-methylbenzofuran in synthetic organic chemistry, often as an intermediate in the production of more complex molecules. Its unique structure allows for numerous synthetic pathways.

As quoted by eminent chemists, "The beauty of organic compounds lies not just in their structure, but in the potential they hold for innovation." This is particularly true for 5-methylbenzofuran, which opens doors to new research avenues and novel applications in medicinal chemistry and beyond.

In summary, 5-methylbenzofuran stands out not only for its unique chemical structure but also for its promising applications in the field of science. With ongoing research, this compound may lead to significant breakthroughs in various domains.

Synonyms
5-Methylbenzofuran
18441-43-5
GLM9ZJ1WW7
DTXSID90171571
RefChem:1073142
DTXCID1094062
242-318-4
5-methyl-1-benzofuran
Benzofuran, 5-methyl-
5-methyl-benzofuran
MFCD00138124
EINECS 242-318-4
5-methyl-benzo[b]furan
UNII-GLM9ZJ1WW7
SCHEMBL172397
SCHEMBL207520
SCHEMBL209082
SCHEMBL317485
SCHEMBL596938
SCHEMBL2096028
SCHEMBL21295697
SCHEMBL30455978
TAA44143
AC2085
AKOS006275454
MB00739
CS-11213
SY009697
DB-082599
CS-0309087
NS00026052
EN300-156048
Z1198151070
InChI=1/C9H8O/c1-7-2-3-9-8(6-7)4-5-10-9/h2-6H,1H