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2-Amino-5-methylthio-1,3,4-thiadiazole

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Identification
Molecular formula
C3H5N3S2
CAS number
2349-67-9
IUPAC name
5-methylsulfanyl-1,3,4-thiadiazol-2-amine
State
State

At room temperature, this compound is solid, generally appearing as crystalline in nature.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.15
General information
Molecular weight
148.22g/mol
Molar mass
148.2170g/mol
Density
1.4700g/cm3
Appearence

2-Amino-5-methylthio-1,3,4-thiadiazole typically appears as a solid at room temperature. It may be present in the form of white to off-white crystals.

Comment on solubility

Solubility of 5-methylsulfanyl-1,3,4-thiadiazol-2-amine

The solubility of 5-methylsulfanyl-1,3,4-thiadiazol-2-amine can be influenced by several factors, including its molecular structure and environmental conditions. Here are key aspects to consider regarding its solubility:

  • Polarity: The presence of the thiadiazol ring and the methylsulfanyl group can affect the overall polarity of the molecule. Generally, compounds with higher polarity tend to dissolve better in polar solvents such as water.
  • Hydrogen Bonding: If the compound can form hydrogen bonds, this would enhance its solubility in polar solvents. Investigating whether 5-methylsulfanyl-1,3,4-thiadiazol-2-amine can engage in such interactions is crucial.
  • Solvent Compatibility: Compatibility with various solvents like ethanol, acetone, or dimethyl sulfoxide (DMSO) should be explored, as organic solvents may help dissolve the compound effectively.
  • Temperature Effect: As with many chemical compounds, increasing temperature can also increase solubility. Conducting experiments at varying temperatures could yield useful data.

In summary, understanding the solubility characteristics of 5-methylsulfanyl-1,3,4-thiadiazol-2-amine is not only key for its practical applications but also for further explorations in chemical synthesis and pharmacology. As the saying goes, “Like dissolves like,” and the interactions within the molecule will largely dictate its solubility behavior in various environments.

Interesting facts

Interesting Facts about 5-methylsulfanyl-1,3,4-thiadiazol-2-amine

5-methylsulfanyl-1,3,4-thiadiazol-2-amine is a fascinating compound that belongs to the class of thiadiazoles, recognized for their diverse applications in the fields of chemistry and pharmacology. Here are some notable aspects to consider:

  • Structure and Functionality: This compound features a unique ring structure that includes sulfur and nitrogen atoms, which contribute to its reactivity and potential applications. The substitution with a methylsulfanyl group enhances its chemical properties, making it an intriguing subject for research.
  • Biological Significance: Compounds in the thiadiazole family are known for exhibiting biological activities. They are often studied for their antimicrobial, antifungal, and anticancer properties, which opens avenues for new drug development.
  • Synthetic Pathways: The synthesis of 5-methylsulfanyl-1,3,4-thiadiazol-2-amine can be achieved via various methods that involve the reaction of thiocarbohydrazide with carbon disulfide and subsequent treatment with amines. This synthetic versatility adds to its appeal in chemical research.
  • Potential Uses: Due to its potential as an agrochemical, this compound has drawn attention in crop protection studies. Researchers are exploring its efficacy against pests and pathogens that threaten agricultural yields.
  • Research & Innovation: The compound is a subject of ongoing studies aimed at understanding its mechanism of action and exploring novel derivatives that might enhance its biological activity or improve selectivity.

As an intersection of chemistry, biology, and agriculture, 5-methylsulfanyl-1,3,4-thiadiazol-2-amine stands out as a compound that inspires further examination and innovation. It exemplifies how small molecular changes can lead to significant variations in activity and potential applications across multiple disciplines.

Synonyms
5-(Methylsulfanyl)-1,3,4-thiadiazol-2-amine
672-510-7
5319-77-7
2-Amino-5-(methylthio)-1,3,4-thiadiazole
5-(Methylthio)-1,3,4-thiadiazol-2-amine
1,3,4-Thiadiazol-2-amine, 5-(methylthio)-
5-methylsulfanyl-1,3,4-thiadiazol-2-amine
1,3,4-THIADIAZOLE, 2-AMINO-5-(METHYLTHIO)-
2-Amino-5-methylthio-1,3,4-thiadiazole
MFCD00175752
2-Amino-5-methylmercapto-1,3,4-thiadiazole
NSC-67524
NSC 67524
BRN 0118749
NSC67524
4-27-00-08165 (Beilstein Handbook Reference)
SCHEMBL750885
CHEMBL174202
DTXSID70201249
CHEBI:194593
4766G46MED
GEO-00174
STK722184
AKOS000112106
PS-4558
2-Amino-5-methylthio-1,3,4-thidiazole
5-methylthio-2-amino-1,3,4-thiadiazole
SY063539
1,4-Thiadiazol-2-amine, 5-(methylthio)-
2-Amino-5-methyl thio-1,3,4-thiadiazole
5-methylsulanyl-1,3,4-thiadiazol-2-amine
DB-004645
1,4-Thiadiazole, 2-amino-5-(methylthio)-
EN300-1263664
5-(Methylsulfanyl)-1,3,4-thiadiazol-2-amine #
2-Amino-5-(methylthio)-1,3,4-thiadiazole, 99%
Z18452635
F1386-0088